8u6y
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Preholo-Proteasome from Beta 3 D205 deletion== | |
| - | + | <StructureSection load='8u6y' size='340' side='right'caption='[[8u6y]], [[Resolution|resolution]] 2.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8u6y]] is a 20 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8U6Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8U6Y FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.8Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8u6y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8u6y OCA], [https://pdbe.org/8u6y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8u6y RCSB], [https://www.ebi.ac.uk/pdbsum/8u6y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8u6y ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PSA2_YEAST PSA2_YEAST] The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Saccharomyces cerevisiae S288C]] | ||
| + | [[Category: Blickling M]] | ||
| + | [[Category: Hanna J]] | ||
| + | [[Category: Rawson S]] | ||
| + | [[Category: Razi A]] | ||
| + | [[Category: Velez B]] | ||
| + | [[Category: Walsh Jr RM]] | ||
Revision as of 05:30, 17 April 2024
Preholo-Proteasome from Beta 3 D205 deletion
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