This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1o84

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1o84.jpg|left|200px]]
+
{{Seed}}
 +
[[Image:1o84.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1o84| PDB=1o84 | SCENE= }}
{{STRUCTURE_1o84| PDB=1o84 | SCENE= }}
-
'''CRYSTAL STRUCTURE OF BACTERIOCIN AS-48. N-DECYL-BETA-D-MALTOSIDE BOUND.'''
+
===CRYSTAL STRUCTURE OF BACTERIOCIN AS-48. N-DECYL-BETA-D-MALTOSIDE BOUND.===
-
==Overview==
+
<!--
-
The bacteriocin AS-48 is a membrane-interacting peptide, which displays a broad anti-microbial spectrum against Gram-positive and Gram-negative bacteria. The NMR structure of AS-48 at pH 3 has been solved. The analysis of this structure suggests that the mechanism of AS-48 anti-bacterial activity involves the accumulation of positively charged molecules at the membrane surface leading to a disruption of the membrane potential. Here, we report the high-resolution crystal structure of AS-48 and sedimentation equilibrium experiments showing that this bacteriocin is able to adopt different oligomeric structures according to the physicochemical environment. The analysis of these structures suggests a mechanism for molecular function of AS-48 involving a transition from a water-soluble form to a membrane-bound state upon membrane binding.
+
The line below this paragraph, {{ABSTRACT_PUBMED_14623193}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 14623193 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_14623193}}
==About this Structure==
==About this Structure==
Line 35: Line 39:
[[Category: Protein crystallography]]
[[Category: Protein crystallography]]
[[Category: Protein membrane interaction]]
[[Category: Protein membrane interaction]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 03:30:22 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 16:37:25 2008''

Revision as of 13:37, 29 July 2008

Image:1o84.png

Template:STRUCTURE 1o84

CRYSTAL STRUCTURE OF BACTERIOCIN AS-48. N-DECYL-BETA-D-MALTOSIDE BOUND.

Template:ABSTRACT PUBMED 14623193

About this Structure

1O84 is a Single protein structure of sequence from Enterococcus faecalis. Full crystallographic information is available from OCA.

Reference

Structure of bacteriocin AS-48: from soluble state to membrane bound state., Sanchez-Barrena MJ, Martinez-Ripoll M, Galvez A, Valdivia E, Maqueda M, Cruz V, Albert A, J Mol Biol. 2003 Nov 28;334(3):541-9. PMID:14623193

Page seeded by OCA on Tue Jul 29 16:37:25 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1o84"
Personal tools