1ocz

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[[Image:1ocz.gif|left|200px]]
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{{Seed}}
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{{STRUCTURE_1ocz| PDB=1ocz | SCENE= }}
{{STRUCTURE_1ocz| PDB=1ocz | SCENE= }}
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'''BOVINE HEART CYTOCHROME C OXIDASE IN AZIDE-BOUND STATE'''
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===BOVINE HEART CYTOCHROME C OXIDASE IN AZIDE-BOUND STATE===
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==Overview==
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Crystal structures of bovine heart cytochrome c oxidase in the fully oxidized, fully reduced, azide-bound, and carbon monoxide-bound states were determined at 2.30, 2.35, 2.9, and 2.8 angstrom resolution, respectively. An aspartate residue apart from the O2 reduction site exchanges its effective accessibility to the matrix aqueous phase for one to the cytosolic phase concomitantly with a significant decrease in the pK of its carboxyl group, on reduction of the metal sites. The movement indicates the aspartate as the proton pumping site. A tyrosine acidified by a covalently linked imidazole nitrogen is a possible proton donor for the O2 reduction by the enzyme.
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The line below this paragraph, {{ABSTRACT_PUBMED_9624044}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 9624044 is the PubMed ID number.
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{{ABSTRACT_PUBMED_9624044}}
==About this Structure==
==About this Structure==
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[[Category: Azide-bound]]
[[Category: Azide-bound]]
[[Category: Cytochrome c oxidase]]
[[Category: Cytochrome c oxidase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 03:41:01 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 15:26:30 2008''

Revision as of 12:26, 28 July 2008

Image:1ocz.png

Template:STRUCTURE 1ocz

BOVINE HEART CYTOCHROME C OXIDASE IN AZIDE-BOUND STATE

Template:ABSTRACT PUBMED 9624044

About this Structure

1OCZ is a Protein complex structure of sequences from Bos taurus. Full crystallographic information is available from OCA.

Reference

Redox-coupled crystal structural changes in bovine heart cytochrome c oxidase., Yoshikawa S, Shinzawa-Itoh K, Nakashima R, Yaono R, Yamashita E, Inoue N, Yao M, Fei MJ, Libeu CP, Mizushima T, Yamaguchi H, Tomizaki T, Tsukihara T, Science. 1998 Jun 12;280(5370):1723-9. PMID:9624044

Page seeded by OCA on Mon Jul 28 15:26:30 2008

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