6jzv
From Proteopedia
(Difference between revisions)
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<StructureSection load='6jzv' size='340' side='right'caption='[[6jzv]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='6jzv' size='340' side='right'caption='[[6jzv]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'> | + | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JZV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6JZV FirstGlance]. <br> |
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6jzv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jzv OCA], [https://pdbe.org/6jzv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6jzv RCSB], [https://www.ebi.ac.uk/pdbsum/6jzv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6jzv ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6jzv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jzv OCA], [https://pdbe.org/6jzv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6jzv RCSB], [https://www.ebi.ac.uk/pdbsum/6jzv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6jzv ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| - | == Function == | ||
| - | [https://www.uniprot.org/uniprot/SUFU_BACSU SUFU_BACSU] Its function is controversial. Has been generally assumed to be an iron-sulfur cluster assembly scaffold protein (PubMed:20097860, PubMed:21236255), but more recent evidence suggest it is a sulfurtransferase rather than a scaffold assembly protein (PubMed:24321018). Has been shown to bind low levels of a labile, air-sensitive Fe-S cluster; this can be assembled under anaerobic conditions from FeCl(3) and Li(2)S. Has been shown to be able to transfer this Fe-S cluster to an acceptor protein. Stimulates the cysteine desulfurase activity of SufS, for which it acts as a second substrate. Alkylation eliminates its ability to stimulate SufS. A mixture of SufS, SufU, Fra and L-cysteine is able to reconstitute Fe-S clusters on apo-aconitase (citB), reconstituting aconitase activity.<ref>PMID:20097860</ref> <ref>PMID:20822158</ref> <ref>PMID:21236255</ref> <ref>PMID:21744456</ref> <ref>PMID:24321018</ref> | ||
==See Also== | ==See Also== | ||
*[[Sulfurtransferase|Sulfurtransferase]] | *[[Sulfurtransferase|Sulfurtransferase]] | ||
| - | == References == | ||
| - | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Bacillus subtilis subsp. subtilis str. 168]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Fujishiro T]] | [[Category: Fujishiro T]] | ||
[[Category: Takahashi Y]] | [[Category: Takahashi Y]] | ||
Current revision
Crystal structure of SufU from Bacillus subtilis
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