5nzs
From Proteopedia
(Difference between revisions)
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== Function == | == Function == | ||
| - | [https://www.uniprot.org/uniprot/ | + | [https://www.uniprot.org/uniprot/COPA_MOUSE COPA_MOUSE] The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity). Xenin stimulates exocrine pancreatic secretion. It inhibits pentagastrin-stimulated secretion of acid, to induce exocrine pancreatic secretion and to affect small and large intestinal motility. In the gut, xenin interacts with the neurotensin receptor (By similarity). |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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<div class="pdbe-citations 5nzs" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5nzs" style="background-color:#fffaf0;"></div> | ||
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| + | ==See Also== | ||
| + | *[[Coatomer 3D structures|Coatomer 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
Current revision
The structure of the COPI coat leaf in complex with the ArfGAP2 uncoating factor
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