8r4n
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of neutralizing Fab Eq4.Dp46-3A from equine antivenom bound to short chain three finger alpha-neurotoxin from Dendroaspis polylepis.== | |
| - | + | <StructureSection load='8r4n' size='340' side='right'caption='[[8r4n]], [[Resolution|resolution]] 2.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8r4n]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Dendroaspis_polylepis Dendroaspis polylepis] and [https://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8R4N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8R4N FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8r4n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8r4n OCA], [https://pdbe.org/8r4n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8r4n RCSB], [https://www.ebi.ac.uk/pdbsum/8r4n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8r4n ProSAT]</span></td></tr> |
| - | [[Category: Wibmer | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/3S11_DENPO 3S11_DENPO] Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission.[UniProtKB:P60775] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Dendroaspis polylepis]] | ||
| + | [[Category: Equus caballus]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Wibmer CK]] | ||
Current revision
Crystal structure of neutralizing Fab Eq4.Dp46-3A from equine antivenom bound to short chain three finger alpha-neurotoxin from Dendroaspis polylepis.
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