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8wuy
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of TR3 LBD in complex with para-positioned 3,4,5-trisubstituted benzene derivatives== | |
| - | + | <StructureSection load='8wuy' size='340' side='right'caption='[[8wuy]], [[Resolution|resolution]] 2.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8wuy]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8WUY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8WUY FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=XBF:~{N}-methyl-~{N}-octyl-3,4,5-tris(oxidanyl)benzamide'>XBF</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8wuy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8wuy OCA], [https://pdbe.org/8wuy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8wuy RCSB], [https://www.ebi.ac.uk/pdbsum/8wuy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8wuy ProSAT]</span></td></tr> |
| - | [[Category: Chen | + | </table> |
| - | [[Category: Lin | + | == Function == |
| + | [https://www.uniprot.org/uniprot/NR4A1_HUMAN NR4A1_HUMAN] Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3' (By similarity). May inhibit NF-kappa-B transactivation of IL2.<ref>PMID:15466594</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Chen XQ]] | ||
| + | [[Category: Hong WB]] | ||
| + | [[Category: Lin TW]] | ||
Current revision
Crystal Structure of TR3 LBD in complex with para-positioned 3,4,5-trisubstituted benzene derivatives
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