This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1opb

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1opb.jpg|left|200px]]
+
{{Seed}}
 +
[[Image:1opb.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1opb| PDB=1opb | SCENE= }}
{{STRUCTURE_1opb| PDB=1opb | SCENE= }}
-
'''THE CRYSTAL STRUCTURES OF HOLO-AND APO-CELLULAR RETINOL BINDING PROTEIN II'''
+
===THE CRYSTAL STRUCTURES OF HOLO-AND APO-CELLULAR RETINOL BINDING PROTEIN II===
-
==Overview==
+
<!--
-
Apo and holo-cellular retinol-binding protein II have been crystallized, and their crystal structures have been determined to 2.1 A and 1.9 A respectively. The apo and holo-crystals have different but related triclinic space groups. The X-ray phases for both structures were determined using the molecular replacement method. The crystal co-ordinates were refined to an R-factor of 0.200 for apo, and 0.173 for holo-cellular retinol-binding protein II. The holo and apo-models have nearly the same tertiary structures. Cellular retinol-binding protein II consists of a ten-stranded anti-parallel beta-barrel with the ligand binding cavity within the barrel. Two alpha-helices cover the open end of the beta-barrel making it almost solvent inaccessible. A single portal large enough to admit a water molecule was observed opening into the binding cavity. Exogenously added retinol was found within the cavity of each holo-cellular retinol-binding protein II molecule. Each retinol was surrounded by both polar and non-polar residues. The hydroxyl group of the bound retinol hydrogen bonds to the amide group of glutamine 108. The overall conformation of the bound retinol was derived from the four different molecules of holo-cellular retinol-binding protein II present in the triclinic form. The four copies of bound retinol had essentially the same conformation as found in crystalline retinaldehyde.
+
The line below this paragraph, {{ABSTRACT_PUBMED_8487303}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 8487303 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_8487303}}
==About this Structure==
==About this Structure==
Line 25: Line 29:
[[Category: Winter, N.]]
[[Category: Winter, N.]]
[[Category: Retinol transport]]
[[Category: Retinol transport]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 04:07:26 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 06:08:24 2008''

Revision as of 03:08, 29 July 2008

Image:1opb.png

Template:STRUCTURE 1opb

THE CRYSTAL STRUCTURES OF HOLO-AND APO-CELLULAR RETINOL BINDING PROTEIN II

Template:ABSTRACT PUBMED 8487303

About this Structure

1OPB is a Single protein structure of sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

Crystal structures of holo and apo-cellular retinol-binding protein II., Winter NS, Bratt JM, Banaszak LJ, J Mol Biol. 1993 Apr 20;230(4):1247-59. PMID:8487303

Page seeded by OCA on Tue Jul 29 06:08:24 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1opb"
Personal tools