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8r1l
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of avian H5N1 influenza A polymerase in complex with human ANP32B.== | |
| - | + | <StructureSection load='8r1l' size='340' side='right'caption='[[8r1l]], [[Resolution|resolution]] 3.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8r1l]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Influenza_A_virus Influenza A virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8R1L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8R1L FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.1Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8r1l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8r1l OCA], [https://pdbe.org/8r1l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8r1l RCSB], [https://www.ebi.ac.uk/pdbsum/8r1l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8r1l ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/AN32B_HUMAN AN32B_HUMAN] Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity (By similarity). Exhibits histone chaperone properties, stimulating core histones to assemble into a nucleosome.<ref>PMID:20538007</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Influenza A virus]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Carrique L]] | ||
| + | [[Category: Fan H]] | ||
| + | [[Category: Fodor E]] | ||
| + | [[Category: Grimes JM]] | ||
| + | [[Category: Keown JR]] | ||
| + | [[Category: Staller E]] | ||
Revision as of 08:33, 9 May 2024
Structure of avian H5N1 influenza A polymerase in complex with human ANP32B.
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Categories: Homo sapiens | Influenza A virus | Large Structures | Carrique L | Fan H | Fodor E | Grimes JM | Keown JR | Staller E
