1owx

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1owx.jpg|left|200px]]
+
{{Seed}}
 +
[[Image:1owx.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1owx| PDB=1owx | SCENE= }}
{{STRUCTURE_1owx| PDB=1owx | SCENE= }}
-
'''Solution structure of the C-terminal RRM of human La (La225-334)'''
+
===Solution structure of the C-terminal RRM of human La (La225-334)===
-
==Overview==
+
<!--
-
The La protein is an important component of ribonucleoprotein complexes that acts mainly as an RNA chaperone to facilitate correct processing and maturation of RNA polymerase III transcripts, but can also stimulate translation initiation. We report here the structure of the C-terminal domain of human La, which comprises an atypical RNA recognition motif (La225-334) and a long unstructured C-terminal tail. The central beta sheet of La225-334 reveals novel features: the putative RNA binding surface is formed by a five-stranded beta sheet and, strikingly, is largely obscured by a long C-terminal alpha helix that encompasses a recently identified nuclear retention element. Contrary to previous observations, we find that the La protein does not contain a dimerization domain.
+
The line below this paragraph, {{ABSTRACT_PUBMED_12842046}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 12842046 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_12842046}}
==About this Structure==
==About this Structure==
-
1OWX is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OWX OCA].
+
1OWX is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OWX OCA].
==Reference==
==Reference==
Line 30: Line 34:
[[Category: Manolaridis, I.]]
[[Category: Manolaridis, I.]]
[[Category: Rrm]]
[[Category: Rrm]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 04:22:50 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 15:10:12 2008''

Revision as of 12:10, 28 July 2008

Image:1owx.png

Template:STRUCTURE 1owx

Solution structure of the C-terminal RRM of human La (La225-334)

Template:ABSTRACT PUBMED 12842046

About this Structure

1OWX is a Single protein structure of sequence from Homo sapiens. Full experimental information is available from OCA.

Reference

Structure of the C-terminal domain of human La protein reveals a novel RNA recognition motif coupled to a helical nuclear retention element., Jacks A, Babon J, Kelly G, Manolaridis I, Cary PD, Curry S, Conte MR, Structure. 2003 Jul;11(7):833-43. PMID:12842046

Page seeded by OCA on Mon Jul 28 15:10:12 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1owx"
Personal tools