Amiodarone

(Difference between revisions)

Revision as of 13:23, 18 December 2023

↑ "Amiodarone Hydrochloride". The American Society of Health-System Pharmacists. Archived from the original on 19 September 2016. Retrieved 22 August 2016

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 Amiodarone is an antiarrhythmic medication used to treat and prevent a number of types of cardiac dysrhythmias. This includes ventricular tachycardia (VT), ventricular fibrillation (VF), and wide complex tachycardia, as well as atrial fibrillation and paroxysmal supraventricular tachycardia.<ref name="a4">[https://www.drugs.com/monograph/amiodarone.html "Amiodarone Hydrochloride".] The American Society of Health-System Pharmacists. Archived from the original on 19 September 2016. Retrieved 22 August 2016</ref> See also [https://en.wikipedia.org/wiki/Amiodarone Amiodarone].
+Amiodarone is categorized as a class III antiarrhythmic agent, and prolongs phase 3 of the cardiac action potential, the repolarization phase where there is normally decreased calcium permeability and increased potassium permeability. It has numerous other effects, however, including actions that are similar to those of antiarrhythmic classes Ia, II, and IV.
+Amiodarone is a blocker of voltage gated potassium (KCNH2) and voltage gated calcium channels (CACNA2D2).[50]
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