1p1y

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{{STRUCTURE_1p1y| PDB=1p1y | SCENE= }}
{{STRUCTURE_1p1y| PDB=1p1y | SCENE= }}
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'''Crystal structure of a continuous three-dimensional DNA lattice from d(GGACAGATGGGAG)'''
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===Crystal structure of a continuous three-dimensional DNA lattice from d(GGACAGATGGGAG)===
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==Overview==
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DNA has proved to be a versatile material for the rational design and assembly of nanometer scale objects. Here we report the crystal structure of a continuous three-dimensional DNA lattice formed by the self-assembly of a DNA 13-mer. The structure consists of stacked layers of parallel helices with adjacent layers linked through parallel-stranded base pairing. The hexagonal lattice geometry contains solvent channels that appear large enough to allow 3'-linked guest molecules into the crystal. We have successfully used these parallel base pairs to design and produce crystals with greatly enlarged solvent channels. This lattice may have applications as a molecular scaffold for structure determination of guest molecules, as a molecular sieve, or in the assembly of molecular electronics. Predictable non-Watson-Crick base pairs, like those described here, may present a new tool in structural DNA nanotechnology.
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(as it appears on PubMed at http://www.pubmed.gov), where 15324813 is the PubMed ID number.
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{{ABSTRACT_PUBMED_15324813}}
==About this Structure==
==About this Structure==
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[[Category: Continuous three-dimensional dna lattice]]
[[Category: Continuous three-dimensional dna lattice]]
[[Category: Parallel-stranded base pair]]
[[Category: Parallel-stranded base pair]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 04:34:46 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 16:43:30 2008''

Revision as of 13:43, 28 July 2008

Image:1p1y.png

Template:STRUCTURE 1p1y

Crystal structure of a continuous three-dimensional DNA lattice from d(GGACAGATGGGAG)

Template:ABSTRACT PUBMED 15324813

About this Structure

Full crystallographic information is available from OCA.

Reference

Crystal structure of a continuous three-dimensional DNA lattice., Paukstelis PJ, Nowakowski J, Birktoft JJ, Seeman NC, Chem Biol. 2004 Aug;11(8):1119-26. PMID:15324813

Page seeded by OCA on Mon Jul 28 16:43:30 2008

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