1p7b

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[[Image:1p7b.gif|left|200px]]
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{{STRUCTURE_1p7b| PDB=1p7b | SCENE= }}
{{STRUCTURE_1p7b| PDB=1p7b | SCENE= }}
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'''Crystal structure of an inward rectifier potassium channel'''
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===Crystal structure of an inward rectifier potassium channel===
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==Overview==
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The KirBac1.1 channel belongs to the inward-rectifier family of potassium channels. Here we report the structure of the entire prokaryotic Kir channel assembly, in the closed state, refined to a resolution of 3.65 angstroms. We identify the main activation gate and structural elements involved in gating. On the basis of structural evidence presented here, we suggest that gating involves coupling between the intracellular and membrane domains. This further suggests that initiation of gating by membrane or intracellular signals represents different entry points to a common mechanistic pathway.
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(as it appears on PubMed at http://www.pubmed.gov), where 12738871 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12738871}}
==About this Structure==
==About this Structure==
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[[Category: Ion conduction]]
[[Category: Ion conduction]]
[[Category: Transmembrane helice]]
[[Category: Transmembrane helice]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 04:46:31 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 05:40:59 2008''

Revision as of 02:41, 29 July 2008

Image:1p7b.png

Template:STRUCTURE 1p7b

Crystal structure of an inward rectifier potassium channel

Template:ABSTRACT PUBMED 12738871

About this Structure

1P7B is a Single protein structure of sequence from Burkholderia pseudomallei. Full crystallographic information is available from OCA.

Reference

Crystal structure of the potassium channel KirBac1.1 in the closed state., Kuo A, Gulbis JM, Antcliff JF, Rahman T, Lowe ED, Zimmer J, Cuthbertson J, Ashcroft FM, Ezaki T, Doyle DA, Science. 2003 Jun 20;300(5627):1922-6. Epub 2003 May 8. PMID:12738871

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