8xif

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'''Unreleased structure'''
 
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The entry 8xif is ON HOLD until Paper Publication
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==The crystal structure of the AEP domain of VACV D5==
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<StructureSection load='8xif' size='340' side='right'caption='[[8xif]], [[Resolution|resolution]] 1.39&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8xif]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Vaccinia_virus Vaccinia virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8XIF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8XIF FirstGlance]. <br>
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Description:
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.39&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PPV:PYROPHOSPHATE'>PPV</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8xif FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8xif OCA], [https://pdbe.org/8xif PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8xif RCSB], [https://www.ebi.ac.uk/pdbsum/8xif PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8xif ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PG117_VACCW PG117_VACCW] Multifunctional protein required for genome uncoating and replication (PubMed:18000036, PubMed:17093187, PubMed:26912611). Major viral uncoating protein that is required for the release of the viral genome from incoming viral cores containing the viral DNA genome (PubMed:24439902). Possesses an ATPase activity that is required for hexamerization and uncoating (PubMed:24439902, PubMed:26912611).<ref>PMID:12490386</ref> <ref>PMID:17093187</ref> <ref>PMID:18000036</ref> <ref>PMID:24439902</ref> <ref>PMID:26912611</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Vaccinia virus]]
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[[Category: Gan J]]
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[[Category: Zhang W]]

Revision as of 06:25, 1 May 2024

The crystal structure of the AEP domain of VACV D5

PDB ID 8xif

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