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7qqe

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Current revision (05:37, 24 December 2025) (edit) (undo)
 
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== Disease ==
== Disease ==
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[https://www.uniprot.org/uniprot/NFIX_HUMAN NFIX_HUMAN] 19p13.3 microduplication syndrome;Malan overgrowth syndrome;Marshall-Smith syndrome. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry.
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[https://www.uniprot.org/uniprot/NFIX_HUMAN NFIX_HUMAN] Marshall-Smith syndrome;Malan overgrowth syndrome;19p13.3 microduplication syndrome. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry.
== Function ==
== Function ==
[https://www.uniprot.org/uniprot/NFIX_HUMAN NFIX_HUMAN] Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.
[https://www.uniprot.org/uniprot/NFIX_HUMAN NFIX_HUMAN] Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

Current revision

Nuclear factor one X - NFIX in P41212

PDB ID 7qqe

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