This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1pzd

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1pzd.gif|left|200px]]
+
{{Seed}}
 +
[[Image:1pzd.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1pzd| PDB=1pzd | SCENE= }}
{{STRUCTURE_1pzd| PDB=1pzd | SCENE= }}
-
'''Structural Identification of a conserved appendage domain in the carboxyl-terminus of the COPI gamma-subunit.'''
+
===Structural Identification of a conserved appendage domain in the carboxyl-terminus of the COPI gamma-subunit.===
-
==Overview==
+
<!--
-
The formation of coated vesicles is a fundamental step in many intracellular trafficking pathways. COPI and clathrin represent two important and distinct sets of vesicle coating machinery, involved primarily in mediating intra-Golgi and endocytic transport, respectively. Here we identify an important functional region at the carboxyl terminus of the gamma subunit of the COPI complex (gammaCOP) and describe the X-ray crystal structure of this domain at 2.3 A resolution. This domain of gammaCOP exhibits unexpected structural similarity to the carboxyl-terminal appendage domains of the alpha and beta subunits of the AP2 adaptor proteins, integral components of clathrin-coated vesicles. The remarkable structural conservation exhibited by the gammaCOP appendage domain, coupled with functional data and primary sequence analysis, supports a model of COPI function with significant structural and mechanistic parallels to vesicular transport by the clathrin/AP2 system.
+
The line below this paragraph, {{ABSTRACT_PUBMED_14527408}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 14527408 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_14527408}}
==About this Structure==
==About this Structure==
Line 29: Line 33:
[[Category: Ear domain]]
[[Category: Ear domain]]
[[Category: Platform domain]]
[[Category: Platform domain]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 05:40:36 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 13:54:55 2008''

Revision as of 10:54, 28 July 2008

Image:1pzd.png

Template:STRUCTURE 1pzd

Structural Identification of a conserved appendage domain in the carboxyl-terminus of the COPI gamma-subunit.

Template:ABSTRACT PUBMED 14527408

About this Structure

1PZD is a Single protein structure of sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

Conserved structural motifs in intracellular trafficking pathways: structure of the gammaCOP appendage domain., Hoffman GR, Rahl PB, Collins RN, Cerione RA, Mol Cell. 2003 Sep;12(3):615-25. PMID:14527408

Page seeded by OCA on Mon Jul 28 13:54:55 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1pzd"
Personal tools