1qa6

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[[Image:1qa6.gif|left|200px]]
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{{Seed}}
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[[Image:1qa6.png|left|200px]]
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{{STRUCTURE_1qa6| PDB=1qa6 | SCENE= }}
{{STRUCTURE_1qa6| PDB=1qa6 | SCENE= }}
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'''CRYSTAL STRUCTURE OF A CONSERVED RIBOSOMAL PROTEIN-RNA COMPLEX'''
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===CRYSTAL STRUCTURE OF A CONSERVED RIBOSOMAL PROTEIN-RNA COMPLEX===
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==Overview==
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The structure of a highly conserved complex between a 58-nucleotide domain of large subunit ribosomal RNA and the RNA-binding domain of ribosomal protein L11 has been solved at 2.8 angstrom resolution. It reveals a precisely folded RNA structure that is stabilized by extensive tertiary contacts and contains an unusually large core of stacked bases. A bulge loop base from one hairpin of the RNA is intercalated into the distorted major groove of another helix; the protein locks this tertiary interaction into place by binding to the intercalated base from the minor groove side. This direct interaction with a key ribosomal RNA tertiary interaction suggests that part of the role of L11 is to stabilize an unusual RNA fold within the ribosome.
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The line below this paragraph, {{ABSTRACT_PUBMED_10325228}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 10325228 is the PubMed ID number.
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{{ABSTRACT_PUBMED_10325228}}
==About this Structure==
==About this Structure==
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[[Category: Ribosomal rna]]
[[Category: Ribosomal rna]]
[[Category: Tertiary structur,e rna-protein interaction]]
[[Category: Tertiary structur,e rna-protein interaction]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 06:03:33 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 17:52:54 2008''

Revision as of 14:52, 27 July 2008

Image:1qa6.png

Template:STRUCTURE 1qa6

CRYSTAL STRUCTURE OF A CONSERVED RIBOSOMAL PROTEIN-RNA COMPLEX

Template:ABSTRACT PUBMED 10325228

About this Structure

1QA6 is a Single protein structure of sequence from Geobacillus stearothermophilus. Full crystallographic information is available from OCA.

Reference

Crystal structure of a conserved ribosomal protein-RNA complex., Conn GL, Draper DE, Lattman EE, Gittis AG, Science. 1999 May 14;284(5417):1171-4. PMID:10325228

Page seeded by OCA on Sun Jul 27 17:52:54 2008

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