8rzv

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m (Protected "8rzv" [edit=sysop:move=sysop])
Current revision (13:17, 13 March 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8rzv is ON HOLD
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==Structure of UP1 S4ES6E phosphomimetic mutant in complex with human telomeric repeat DNA==
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<StructureSection load='8rzv' size='340' side='right'caption='[[8rzv]], [[Resolution|resolution]] 1.51&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8rzv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8RZV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8RZV FirstGlance]. <br>
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Description:
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.51&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8rzv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8rzv OCA], [https://pdbe.org/8rzv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8rzv RCSB], [https://www.ebi.ac.uk/pdbsum/8rzv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8rzv ProSAT]</span></td></tr>
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</table>
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== Disease ==
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[https://www.uniprot.org/uniprot/ROA1_HUMAN ROA1_HUMAN] Amyotrophic lateral sclerosis;Inclusion body myopathy with Paget disease of bone and frontotemporal dementia. The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:23455423</ref> The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:23455423</ref>
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== Function ==
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[https://www.uniprot.org/uniprot/ROA1_HUMAN ROA1_HUMAN] Involved in the packaging of pre-mRNA into hnRNP particles, transport of poly(A) mRNA from the nucleus to the cytoplasm and may modulate splice site selection. May play a role in HCV RNA replication.<ref>PMID:17229681</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Dunnett L]]
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[[Category: Prischi F]]

Current revision

Structure of UP1 S4ES6E phosphomimetic mutant in complex with human telomeric repeat DNA

PDB ID 8rzv

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OCA

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