This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
8smm
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Xenopus laevis hyaluronan synthase 1== | |
| - | + | <StructureSection load='8smm' size='340' side='right'caption='[[8smm]], [[Resolution|resolution]] 3.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8smm]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8SMM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8SMM FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.2Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8smm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8smm OCA], [https://pdbe.org/8smm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8smm RCSB], [https://www.ebi.ac.uk/pdbsum/8smm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8smm ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: Gorniak | + | == Function == |
| + | [https://www.uniprot.org/uniprot/HYAS1_XENLA HYAS1_XENLA] Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. Also able to catalyze the synthesis of chito-oligosaccharide depending on the substrate.<ref>PMID:3410156</ref> <ref>PMID:9442026</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Xenopus laevis]] | ||
| + | [[Category: Gorniak I]] | ||
| + | [[Category: Zimmer J]] | ||
Current revision
Xenopus laevis hyaluronan synthase 1
| |||||||||||
