1qqe

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1qqe.gif|left|200px]]
+
{{Seed}}
 +
[[Image:1qqe.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1qqe| PDB=1qqe | SCENE= }}
{{STRUCTURE_1qqe| PDB=1qqe | SCENE= }}
-
'''CRYSTAL STRUCTURE OF THE VESICULAR TRANSPORT PROTEIN SEC17'''
+
===CRYSTAL STRUCTURE OF THE VESICULAR TRANSPORT PROTEIN SEC17===
-
==Overview==
+
<!--
-
SNAP proteins play an essential role in membrane trafficking in eukaryotic cells. They activate and recycle SNARE proteins by serving as adaptors between SNAREs and the cytosolic chaperone NSF. We have determined the crystal structure of Sec17, the yeast homolog of alpha-SNAP, to 2.9 A resolution. Sec17 is composed of an N-terminal twisted sheet of alpha-helical hairpins and a C-terminal alpha-helical bundle. The N-terminal sheet has local similarity to the tetratricopeptide repeats from protein phosphatase 5 but has a different overall twist. Sec17 also shares structural features with HEAT and clathrin heavy chain repeats. Possible models of SNAP:SNARE binding suggest that SNAPs may function as lever arms, transmitting forces generated by conformational changes in NSF/Sec18 to drive disassembly of SNARE complexes.
+
The line below this paragraph, {{ABSTRACT_PUBMED_10445030}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 10445030 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_10445030}}
==About this Structure==
==About this Structure==
Line 25: Line 29:
[[Category: Rice, L M.]]
[[Category: Rice, L M.]]
[[Category: Helix-turn-helix tpr-like repeat]]
[[Category: Helix-turn-helix tpr-like repeat]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 06:35:10 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 19:37:29 2008''

Revision as of 16:37, 28 July 2008

Image:1qqe.png

Template:STRUCTURE 1qqe

CRYSTAL STRUCTURE OF THE VESICULAR TRANSPORT PROTEIN SEC17

Template:ABSTRACT PUBMED 10445030

About this Structure

1QQE is a Single protein structure of sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

Crystal structure of the vesicular transport protein Sec17: implications for SNAP function in SNARE complex disassembly., Rice LM, Brunger AT, Mol Cell. 1999 Jul;4(1):85-95. PMID:10445030

Page seeded by OCA on Mon Jul 28 19:37:29 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1qqe"
Personal tools