1qqt

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[[Image:1qqt.gif|left|200px]]
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{{Seed}}
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{{STRUCTURE_1qqt| PDB=1qqt | SCENE= }}
{{STRUCTURE_1qqt| PDB=1qqt | SCENE= }}
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'''METHIONYL-TRNA SYNTHETASE FROM ESCHERICHIA COLI'''
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===METHIONYL-TRNA SYNTHETASE FROM ESCHERICHIA COLI===
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==Overview==
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The 3D structure of monomeric C-truncated Escherichia coli methionyl-tRNA synthetase, a class 1 aminoacyl-tRNA synthetase, has been solved at 2.0 A resolution. Remarkably, the polypeptide connecting the two halves of the Rossmann fold exposes two identical knuckles related by a 2-fold axis but with zinc in the distal knuckle only. Examination of available MetRS orthologs reveals four classes according to the number and zinc content of the putative knuckles. Extreme cases are exemplified by the MetRS of eucaryotic or archaeal origin, where two knuckles and two metal ions are expected, and by the mitochondrial enzymes, which are predicted to have one knuckle without metal ion.
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(as it appears on PubMed at http://www.pubmed.gov), where 10600385 is the PubMed ID number.
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{{ABSTRACT_PUBMED_10600385}}
==About this Structure==
==About this Structure==
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[[Category: Rossmann fold]]
[[Category: Rossmann fold]]
[[Category: Trna ligase]]
[[Category: Trna ligase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 06:35:55 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 07:42:24 2008''

Revision as of 04:42, 28 July 2008

Image:1qqt.png

Template:STRUCTURE 1qqt

METHIONYL-TRNA SYNTHETASE FROM ESCHERICHIA COLI

Template:ABSTRACT PUBMED 10600385

About this Structure

1QQT is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

Crystal structure of Escherichia coli methionyl-tRNA synthetase highlights species-specific features., Mechulam Y, Schmitt E, Maveyraud L, Zelwer C, Nureki O, Yokoyama S, Konno M, Blanquet S, J Mol Biol. 1999 Dec 17;294(5):1287-97. PMID:10600385

Page seeded by OCA on Mon Jul 28 07:42:24 2008

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