User:Merritt Jugo/Sandbox 1
From Proteopedia
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==Introduction== | ==Introduction== | ||
| + | The RNA lariat debranching enzyme, Dbr1, is a metallophosphoesterase that cleaves 2'-5' phosphodiester bonds within intronic lariats. <ref name=”Ransey”>PMID:28504306</ref> | ||
| + | ICP-AES corroborate this finding, and in vitro debranching assays with fluorescently labeled branched substrates confirm activity. | ||
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==Function== | ==Function== | ||
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</StructureSection> | </StructureSection> | ||
==References== | ==References== | ||
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<references/> | <references/> | ||
==Student Contributors== | ==Student Contributors== | ||
*Merritt Jugo | *Merritt Jugo | ||
Revision as of 14:24, 19 March 2024
Merritt's Take on DPPIV
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References
- ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
- ↑ Ransey E, Paredes E, Dey SK, Das SR, Heroux A, Macbeth MR. Crystal structure of the Entamoeba histolytica RNA lariat debranching enzyme EhDbr1 reveals a catalytic Zn(2+) /Mn(2+) heterobinucleation. FEBS Lett. 2017 Jul;591(13):2003-2010. doi: 10.1002/1873-3468.12677. Epub 2017, Jun 14. PMID:28504306 doi:http://dx.doi.org/10.1002/1873-3468.12677
Student Contributors
- Merritt Jugo
