1am5
From Proteopedia
(New page: 200px<br /> <applet load="1am5" size="450" color="white" frame="true" align="right" spinBox="true" caption="1am5, resolution 2.16Å" /> '''THE CRYSTAL STRUCTU...) |
|||
| Line 8: | Line 8: | ||
==About this Structure== | ==About this Structure== | ||
| - | 1AM5 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Gadus_morhua Gadus morhua]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.1 3.4.23.1]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1AM5 OCA]]. | + | 1AM5 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Gadus_morhua Gadus morhua]]. Active as [[http://en.wikipedia.org/wiki/Pepsin_A Pepsin A]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.1 3.4.23.1]]. Structure known Active Site: CAT. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1AM5 OCA]]. |
==Reference== | ==Reference== | ||
Structure and proposed amino-acid sequence of a pepsin from atlantic cod (Gadus morhua)., Karlsen S, Hough E, Olsen RL, Acta Crystallogr D Biol Crystallogr. 1998 Jan 1;54(Pt 1):32-46. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9761815 9761815] | Structure and proposed amino-acid sequence of a pepsin from atlantic cod (Gadus morhua)., Karlsen S, Hough E, Olsen RL, Acta Crystallogr D Biol Crystallogr. 1998 Jan 1;54(Pt 1):32-46. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9761815 9761815] | ||
[[Category: Gadus morhua]] | [[Category: Gadus morhua]] | ||
| + | [[Category: Pepsin A]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Hough, E.]] | [[Category: Hough, E.]] | ||
| Line 21: | Line 22: | ||
[[Category: hydrolase]] | [[Category: hydrolase]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 11:53:18 2007'' |
Revision as of 09:48, 30 October 2007
|
THE CRYSTAL STRUCTURE AND PROPOSED AMINO ACID SEQUENCE OF A PEPSIN FROM ATLANTIC COD (GADUS MORHUA)
Overview
The crystal structure of a pepsin from the gastric mucosa of Atlantic cod, has been determined to 2.16 A resolution. Data were collected on, orthorhombic crystals with cell dimensions a = 35.98, b = 75.40 and c =, 108.10 A, on a FAST area-detector system. The phase problem was solved by, the molecular-replacement method using porcine pepsin (PDB entry 5PEP) as, a search model. The structure has been refined to a crystallographic R, factor of 20.8% using all reflections between 8.0 and 2.16 A, without, prior knowledge of the primary sequence. The resulting crystal structure, is very similar to the porcine enzyme, consisting of two domains with, predominantly beta-sheet structure in the same sequential positions as the, enzyme from pig. In the course of the model building, 122 residues ... [(full description)]
About this Structure
1AM5 is a [Single protein] structure of sequence from [Gadus morhua]. Active as [Pepsin A], with EC number [3.4.23.1]. Structure known Active Site: CAT. Full crystallographic information is available from [OCA].
Reference
Structure and proposed amino-acid sequence of a pepsin from atlantic cod (Gadus morhua)., Karlsen S, Hough E, Olsen RL, Acta Crystallogr D Biol Crystallogr. 1998 Jan 1;54(Pt 1):32-46. PMID:9761815
Page seeded by OCA on Tue Oct 30 11:53:18 2007
