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1rau

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{{STRUCTURE_1rau| PDB=1rau | SCENE= }}
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'''SOLUTION STRUCTURE OF AN UNUSUALLY STABLE RNA TETRAPLEX CONTAINING G-AND U-QUARTET STRUCTURES'''
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===SOLUTION STRUCTURE OF AN UNUSUALLY STABLE RNA TETRAPLEX CONTAINING G-AND U-QUARTET STRUCTURES===
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==Overview==
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A model for the solution structure of an RNA tetraplex, (rUGGGGU)4, has been obtained by two-dimensional NMR spectroscopy and molecular dynamics. The molecule is parallel stranded and Hoogsteen base-paired in 50 mM KCl, and it is so stable that three of its six imino protons have exchange half-lives measured in days at 40 degrees C. The tetraplex is stabilized by base stacking and by the hydrogen bonds in four G quartets and at least one U quartet. This is the first indication of the existence of U-quartet structures of which we are aware.
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The line below this paragraph, {{ABSTRACT_PUBMED_1382577}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 1382577 is the PubMed ID number.
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{{ABSTRACT_PUBMED_1382577}}
==About this Structure==
==About this Structure==
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RAU OCA].
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Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RAU OCA].
==Reference==
==Reference==
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[[Category: Rna]]
[[Category: Rna]]
[[Category: Tetraplex]]
[[Category: Tetraplex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 07:17:08 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 08:47:54 2008''

Revision as of 05:47, 28 July 2008

Image:1rau.png

Template:STRUCTURE 1rau

SOLUTION STRUCTURE OF AN UNUSUALLY STABLE RNA TETRAPLEX CONTAINING G-AND U-QUARTET STRUCTURES

Template:ABSTRACT PUBMED 1382577

About this Structure

Full experimental information is available from OCA.

Reference

Solution structure of an unusually stable RNA tetraplex containing G- and U-quartet structures., Cheong C, Moore PB, Biochemistry. 1992 Sep 15;31(36):8406-14. PMID:1382577

Page seeded by OCA on Mon Jul 28 08:47:54 2008

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