We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.
8oes
From Proteopedia
(Difference between revisions)
| Line 9: | Line 9: | ||
</table> | </table> | ||
== Disease == | == Disease == | ||
| - | [https://www.uniprot.org/uniprot/MUC5B_HUMAN MUC5B_HUMAN] Diffuse panbronchiolitis | + | [https://www.uniprot.org/uniprot/MUC5B_HUMAN MUC5B_HUMAN] Diffuse panbronchiolitis;Idiopathic pulmonary fibrosis;Hypersensitivity pneumonitis. Disease susceptibility is associated with variants affecting the gene represented in this entry. A common polymorphism in the promoter of MUC5B is associated with familial interstitial pneumonia and idiopathic pulmonary fibrosis, suggesting that dysregulated MUC5B expression in the lung may be involved in the pathogenesis of pulmonary fibrosis (PubMed:21506741).<ref>PMID:21506741</ref> |
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/MUC5B_HUMAN MUC5B_HUMAN] Gel-forming mucin that is thought to contribute to the lubricating and viscoelastic properties of whole saliva and cervical mucus. | [https://www.uniprot.org/uniprot/MUC5B_HUMAN MUC5B_HUMAN] Gel-forming mucin that is thought to contribute to the lubricating and viscoelastic properties of whole saliva and cervical mucus. | ||
Current revision
MUC5B amino acids 26-1435 Three beads
| |||||||||||
