User:Camille Gaudet/Sandbox 1
From Proteopedia
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== Introduction == | == Introduction == | ||
=== History === | === History === | ||
| - | In 1902, Bayliss and Starling discover a pancreatic secretin involved in regulation of water homeostasis, giving rise to interest in pancreatic hormones. Shortly after, in 1906, Moore et al. hypothesize involvement of hormone | + | In 1902, [https://en.wikipedia.org/wiki/William_Bayliss Bayliss] and [https://en.wikipedia.org/wiki/Ernest_Starling Starling] discover a pancreatic [https://en.wikipedia.org/wiki/Secretin secretin] involved in regulation of water homeostasis, giving rise to interest in pancreatic hormones. Shortly after, in 1906, Moore et al. hypothesize involvement of [https://en.wikipedia.org/wiki/Gastrointestinal_hormone gastrointestinal hormone extracts] in maintenance of the endocrine pancreas. Finally, in 1929, Jean La Barre purifies glucose-lowering gut extracts, characterizing them as [https://en.wikipedia.org/wiki/Incretin incretins]. |
== General Structure == | == General Structure == | ||
Revision as of 18:03, 1 April 2024
Glucose-dependent Insulinotropic Polypeptide Receptor
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References
- ↑ Sun B, Willard FS, Feng D, Alsina-Fernandez J, Chen Q, Vieth M, Ho JD, Showalter AD, Stutsman C, Ding L, Suter TM, Dunbar JD, Carpenter JW, Mohammed FA, Aihara E, Brown RA, Bueno AB, Emmerson PJ, Moyers JS, Kobilka TS, Coghlan MP, Kobilka BK, Sloop KW. Structural determinants of dual incretin receptor agonism by tirzepatide. Proc Natl Acad Sci U S A. 2022 Mar 29;119(13):e2116506119. PMID:35333651 doi:10.1073/pnas.2116506119
Student Contributors
- Camille Gaudet
