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Sandbox Ben Whiteside

From Proteopedia

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[https://en.wikipedia.org/wiki/Amylin Amylin Peptide]
[https://en.wikipedia.org/wiki/Amylin Amylin Peptide]
== Structure ==
== Structure ==
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=== Transmembrane Domain===
+
<scene name='10/1038828/Entire_protein_scene/3'>Amylin G-Protein Coupled Receptor</scene>
 +
=== Transmembrane Domain ===
 +
=== N Terminal Disulfide ===
=== Receptor Activity Modifying Proteins ===
=== Receptor Activity Modifying Proteins ===
<scene name='10/1038828/Ramp_ctr_interface/3'>RAMP CTR Interface </scene>
<scene name='10/1038828/Ramp_ctr_interface/3'>RAMP CTR Interface </scene>
 +
==== Extracellular Domain - RAMP interactions ====
<scene name='10/1038828/Ctr_ramp_ecd_stablization/2'>RAMP CTR Extracellular Domain Interaction</scene>
<scene name='10/1038828/Ctr_ramp_ecd_stablization/2'>RAMP CTR Extracellular Domain Interaction</scene>
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=== Extracellular Domain ===
+
=== Bypass Motif ===
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<scene name='10/1038828/Entire_protein_scene/3'>Amylin G-Protein Coupled Receptor</scene>
+
=== G-alpha Interactions with CTR TMD ===
== Function ==
== Function ==
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== Relevance ==
 
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== Structural highlights ==
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== Relevance ==
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.

Revision as of 13:10, 2 April 2024

AMYR

AMYR Bound to Amylin

Drag the structure with the mouse to rotate

References

  1. Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
  2. Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
  3. Ransey E, Paredes E, Dey SK, Das SR, Heroux A, Macbeth MR. Crystal structure of the Entamoeba histolytica RNA lariat debranching enzyme EhDbr1 reveals a catalytic Zn(2+) /Mn(2+) heterobinucleation. FEBS Lett. 2017 Jul;591(13):2003-2010. doi: 10.1002/1873-3468.12677. Epub 2017, Jun 14. PMID:28504306 doi:http://dx.doi.org/10.1002/1873-3468.12677
  4. Cao J, Belousoff MJ, Liang YL, Johnson RM, Josephs TM, Fletcher MM, Christopoulos A, Hay DL, Danev R, Wootten D, Sexton PM. A structural basis for amylin receptor phenotype. Science. 2022 Mar 25;375(6587):eabm9609. PMID:35324283 doi:10.1126/science.abm9609


Student Contributors

Ben Whiteside, Mathias Vander Eide, Andrew Helmerich,

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