User:Makenna Marcinek/Sandbox 1

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<scene name='10/1037490/Overlay/7'>Overlay</scene>
<scene name='10/1037490/Overlay/7'>Overlay</scene>
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<scene name='10/1037490/Tirzepatidebonding/6'>Over view of bonds</scene>
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<scene name='10/1037490/Tirzepatidebonding/9'>Over view of bonds</scene>
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<scene name='10/1037490/Tirzepatidebonding/8'>bond 1</scene>
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<scene name='10/1037490/Tirzepatidebonding/10'>bond 1</scene>
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<scene name='10/1037490/Tirzepatidebonding/7'>bond 2 and 3</scene>
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<scene name='10/1037490/Tirzepatidebonding/11'>bond 2 and 3</scene>
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<scene name='10/1037490/Overlay/5'>Shift of bonds</scene>
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<scene name='10/1037490/Overlay/4'>overlay of N-term bonding</scene>
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<scene name='10/1037490/Gvt_binding/3'>glp binding 1</scene>
<scene name='10/1037490/Gvt_binding/3'>glp binding 1</scene>

Revision as of 13:50, 23 April 2024

GLP-1R Homo Sapien

An overview of the entire GLP-1 protein as a spinning cartoon. GLP-1 is shown in green, the GLP-1 receptor in turquoise, and the G-alpha, G-beta, and G-gamma subunits shown in pink, orange, and red respectively. PDB: 6X18

Drag the structure with the mouse to rotate

References

  1. ↑ Zhang X, Belousoff MJ, Zhao P, Kooistra AJ, Truong TT, Ang SY, Underwood CR, Egebjerg T, Šenel P, Stewart GD, Liang YL, Glukhova A, Venugopal H, Christopoulos A, Furness SGB, Miller LJ, Reedtz-Runge S, Langmead CJ, Gloriam DE, Danev R, Sexton PM, Wootten D. Differential GLP-1R Binding and Activation by Peptide and Non-peptide Agonists. Mol Cell. 2020 Nov 5;80(3):485-500.e7. PMID:33027691 doi:10.1016/j.molcel.2020.09.020
  2. ↑ Ransey E, Paredes E, Dey SK, Das SR, Heroux A, Macbeth MR. Crystal structure of the Entamoeba histolytica RNA lariat debranching enzyme EhDbr1 reveals a catalytic Zn(2+) /Mn(2+) heterobinucleation. FEBS Lett. 2017 Jul;591(13):2003-2010. doi: 10.1002/1873-3468.12677. Epub 2017, Jun 14. PMID:28504306 doi:http://dx.doi.org/10.1002/1873-3468.12677

Student Contributors

  • Makenna Marcinek
  • Isabel Kluszynski

Proteopedia Page Contributors and Editors (what is this?)

Makenna Marcinek

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