8jdi
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Cas7-AcrIF25 complex== | |
| - | + | <StructureSection load='8jdi' size='340' side='right'caption='[[8jdi]], [[Resolution|resolution]] 3.37Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8jdi]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Alcanivorax_sp._KX64203 Alcanivorax sp. KX64203] and [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_UCBPP-PA14 Pseudomonas aeruginosa UCBPP-PA14]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8JDI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8JDI FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.372Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8jdi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8jdi OCA], [https://pdbe.org/8jdi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8jdi RCSB], [https://www.ebi.ac.uk/pdbsum/8jdi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8jdi ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CSY3_PSEAB CSY3_PSEAB] CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Cas3 and Cascade participate in CRISPR interference, the third stage of CRISPR immunity (Potential). Involved in crRNA production or stability. The Csy ribonucleoprotein complex binds target ssDNA with high affinity but target dsDNA with much lower affinity.<ref>PMID:21398535</ref> <ref>PMID:22522703</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Alcanivorax sp. KX64203]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Pseudomonas aeruginosa UCBPP-PA14]] | ||
| + | [[Category: Wang J]] | ||
| + | [[Category: Wang Y]] | ||
| + | [[Category: Yang J]] | ||
Current revision
Crystal structure of Cas7-AcrIF25 complex
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