8z0a

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Current revision (07:47, 9 April 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8z0a is ON HOLD
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==Human GYS1-GYG2 complex (apo)==
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<StructureSection load='8z0a' size='340' side='right'caption='[[8z0a]], [[Resolution|resolution]] 2.84&Aring;' scene=''>
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Authors: Chen, P.P., Hsia, K.C.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8z0a]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8Z0A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8Z0A FirstGlance]. <br>
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Description: Human GYS1-GYG2 complex (apo)
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.84&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8z0a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8z0a OCA], [https://pdbe.org/8z0a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8z0a RCSB], [https://www.ebi.ac.uk/pdbsum/8z0a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8z0a ProSAT]</span></td></tr>
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[[Category: Hsia, K.C]]
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</table>
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[[Category: Chen, P.P]]
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== Disease ==
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[https://www.uniprot.org/uniprot/GYS1_HUMAN GYS1_HUMAN] Glycogen storage disease due to muscle and heart glycogen synthase deficiency. The disease is caused by variants affecting the gene represented in this entry.
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== Function ==
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[https://www.uniprot.org/uniprot/GYS1_HUMAN GYS1_HUMAN] Glycogen synthase participates in the glycogen biosynthetic process along with glycogenin and glycogen branching enzyme. Extends the primer composed of a few glucose units formed by glycogenin by adding new glucose units to it. In this context, glycogen synthase transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.<ref>PMID:35835870</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Chen PP]]
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[[Category: Hsia KC]]

Current revision

Human GYS1-GYG2 complex (apo)

PDB ID 8z0a

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