1rrf

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[[Image:1rrf.gif|left|200px]]
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{{STRUCTURE_1rrf| PDB=1rrf | SCENE= }}
{{STRUCTURE_1rrf| PDB=1rrf | SCENE= }}
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'''NON-MYRISTOYLATED RAT ADP-RIBOSYLATION FACTOR-1 COMPLEXED WITH GDP, MONOMERIC CRYSTAL FORM'''
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===NON-MYRISTOYLATED RAT ADP-RIBOSYLATION FACTOR-1 COMPLEXED WITH GDP, MONOMERIC CRYSTAL FORM===
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==Overview==
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The ARFs are a family of 21,000 M(r) proteins with biological roles in constitutive secretion and activation of phospholipase D. The structure of ARF-1 complexed to GDP determined from two crystal forms reveals a topology that is similar to that of the protein p21 ras with two differences: an additional amino-terminal helix and an extra beta-strand. The Mg2+ ion in ARF-1 displays a five-coordination sphere; this feature is not seen in p21 ras, due to a shift in the relative position of the DXXG motif between the two proteins. The occurrence of a dimer in one crystal form suggests that ARF-1 may dimerize during its biological function. The dimer interface involves a region of the ARF-1 molecule that is analogous to the effector domain in p21 ras and may mediate interactions with its effectors.
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The line below this paragraph, {{ABSTRACT_PUBMED_7552752}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 7552752 is the PubMed ID number.
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{{ABSTRACT_PUBMED_7552752}}
==About this Structure==
==About this Structure==
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[[Category: Membrane trafficking]]
[[Category: Membrane trafficking]]
[[Category: Transport protein]]
[[Category: Transport protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 07:49:26 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 19:05:51 2008''

Revision as of 16:05, 28 July 2008

Template:STRUCTURE 1rrf

NON-MYRISTOYLATED RAT ADP-RIBOSYLATION FACTOR-1 COMPLEXED WITH GDP, MONOMERIC CRYSTAL FORM

Template:ABSTRACT PUBMED 7552752

About this Structure

1RRF is a Single protein structure of sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

The structure of rat ADP-ribosylation factor-1 (ARF-1) complexed to GDP determined from two different crystal forms., Greasley SE, Jhoti H, Teahan C, Solari R, Fensome A, Thomas GM, Cockcroft S, Bax B, Nat Struct Biol. 1995 Sep;2(9):797-806. PMID:7552752

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