8zg9

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m (Protected "8zg9" [edit=sysop:move=sysop])
Current revision (05:30, 14 May 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8zg9 is ON HOLD until Paper Publication
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==Y-degron fused ZZ-domain of the Arabidopsis thaliana E3 ubiquitin-protein ligase PRT1==
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<StructureSection load='8zg9' size='340' side='right'caption='[[8zg9]], [[Resolution|resolution]] 1.67&Aring;' scene=''>
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Authors: Yang, W.S., Song, H.K.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8zg9]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8ZG9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8ZG9 FirstGlance]. <br>
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Description: Y-degron fused ZZ-domain of the Arabidopsis thaliana E3 ubiquitin-protein ligase PRT1
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.673&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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[[Category: Yang, W.S]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8zg9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8zg9 OCA], [https://pdbe.org/8zg9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8zg9 RCSB], [https://www.ebi.ac.uk/pdbsum/8zg9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8zg9 ProSAT]</span></td></tr>
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[[Category: Song, H.K]]
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PRT1_ARATH PRT1_ARATH] E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. Functions in the N-end rule pathway of protein degradation, where it specifically recognizes and ubiquitinates proteins with a N-terminal bulky aromatic amino acid (Phe). Does not act on aliphatic hydrophobic and basic N-terminal residues (Arg or Leu) containing proteins.<ref>PMID:11607348</ref> <ref>PMID:14551326</ref> <ref>PMID:17572409</ref> <ref>PMID:9653113</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Arabidopsis thaliana]]
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[[Category: Large Structures]]
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[[Category: Song HK]]
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[[Category: Yang WS]]

Current revision

Y-degron fused ZZ-domain of the Arabidopsis thaliana E3 ubiquitin-protein ligase PRT1

PDB ID 8zg9

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