1s58

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1s58.jpg|left|200px]]
+
{{Seed}}
 +
[[Image:1s58.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1s58| PDB=1s58 | SCENE= }}
{{STRUCTURE_1s58| PDB=1s58 | SCENE= }}
-
'''The structure of B19 parvovirus capsid'''
+
===The structure of B19 parvovirus capsid===
-
==Overview==
+
<!--
-
Human parvovirus B19 is the only parvovirus known to be a human pathogen. The structure of recombinant B19-like particles has been determined to approximately 3.5-A resolution by x-ray crystallography and, to our knowledge, represents the first near-atomic structure of an Erythrovirus. The polypeptide fold of the major capsid protein VP2 is a "jelly roll" with a beta-barrel motif similar to that found in many icosahedral viruses. The large loops connecting the strands of the beta-barrel form surface features that differentiate B19 from other parvoviruses. Although B19 VP2 has only 26% sequence identity to VP3 of adeno-associated virus, 72% of the C(alpha) atoms can be aligned structurally with a rms deviation of 1.8 A. Both viruses require an integrin as a coreceptor, and conserved surface features suggest a common receptor-binding region.
+
The line below this paragraph, {{ABSTRACT_PUBMED_15289612}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 15289612 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_15289612}}
==About this Structure==
==About this Structure==
Line 26: Line 30:
[[Category: Icosahedral capsid]]
[[Category: Icosahedral capsid]]
[[Category: Icosahedral virus]]
[[Category: Icosahedral virus]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 08:18:52 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 06:54:37 2008''

Revision as of 03:54, 28 July 2008

Image:1s58.png

Template:STRUCTURE 1s58

The structure of B19 parvovirus capsid

Template:ABSTRACT PUBMED 15289612

About this Structure

Full crystallographic information is available from OCA.

Reference

The structure of human parvovirus B19., Kaufmann B, Simpson AA, Rossmann MG, Proc Natl Acad Sci U S A. 2004 Aug 10;101(32):11628-33. Epub 2004 Aug 2. PMID:15289612

Page seeded by OCA on Mon Jul 28 06:54:37 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1s58"
Personal tools