8f5a
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8f5a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8f5a OCA], [https://pdbe.org/8f5a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8f5a RCSB], [https://www.ebi.ac.uk/pdbsum/8f5a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8f5a ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8f5a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8f5a OCA], [https://pdbe.org/8f5a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8f5a RCSB], [https://www.ebi.ac.uk/pdbsum/8f5a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8f5a ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| - | == Disease == | ||
| - | [https://www.uniprot.org/uniprot/B2MG_HUMAN B2MG_HUMAN] Defects in B2M are the cause of hypercatabolic hypoproteinemia (HYCATHYP) [MIM:[https://omim.org/entry/241600 241600]. Affected individuals show marked reduction in serum concentrations of immunoglobulin and albumin, probably due to rapid degradation.<ref>PMID:16549777</ref> Note=Beta-2-microglobulin may adopt the fibrillar configuration of amyloid in certain pathologic states. The capacity to assemble into amyloid fibrils is concentration dependent. Persistently high beta(2)-microglobulin serum levels lead to amyloidosis in patients on long-term hemodialysis.<ref>PMID:3532124</ref> <ref>PMID:1336137</ref> <ref>PMID:7554280</ref> <ref>PMID:4586824</ref> <ref>PMID:8084451</ref> <ref>PMID:12119416</ref> <ref>PMID:12796775</ref> <ref>PMID:16901902</ref> <ref>PMID:16491088</ref> <ref>PMID:17646174</ref> <ref>PMID:18835253</ref> <ref>PMID:18395224</ref> <ref>PMID:19284997</ref> | ||
== Function == | == Function == | ||
| - | [https://www.uniprot.org/uniprot/ | + | [https://www.uniprot.org/uniprot/U6BR87_HUMAN U6BR87_HUMAN] |
| - | + | ||
| - | + | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Current revision
Crystal Structure of KS1 TCR in complex with HLA-B*57:01-TW10
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