8s1y

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Current revision (07:54, 5 March 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8s1y is ON HOLD until Paper Publication
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==ThaOS V79A==
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<StructureSection load='8s1y' size='340' side='right'caption='[[8s1y]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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Authors: Basle, A., Ashley, B., Campopiano, D.J., Marles-wright, J.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8s1y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8S1Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8S1Y FirstGlance]. <br>
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Description: ThaOS V79A
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1H4V:(2~{R},4~{R})-5,5-dimethyl-2-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]-1,3-thiazolidine-4-carboxylic+acid'>A1H4V</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
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[[Category: Basle, A]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8s1y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8s1y OCA], [https://pdbe.org/8s1y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8s1y RCSB], [https://www.ebi.ac.uk/pdbsum/8s1y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8s1y ProSAT]</span></td></tr>
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[[Category: Campopiano, D.J]]
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</table>
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[[Category: Ashley, B]]
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== Function ==
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[[Category: Marles-Wright, J]]
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[https://www.uniprot.org/uniprot/BIKB_THET8 BIKB_THET8] Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide (By similarity). Can also use pimeloyl-CoA instead of pimeloyl-ACP as substrate. It also converts 2-amino-3-ketobutyrate and CoA to glycine and acetyl-CoA. Activity is also observed with the following combinations of substrates: acetyl-CoA and either L-alanine or L-serine, pimeloyl-CoA and either glycine or L-serine, and palmitoyl-CoA with L-alanine.<ref>PMID:18071260</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Thermus thermophilus]]
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[[Category: Ashley B]]
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[[Category: Basle A]]
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[[Category: Campopiano DJ]]
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[[Category: Marles-wright J]]

Current revision

ThaOS V79A

PDB ID 8s1y

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