8tft
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Fab of O13-1 human IgG1 antibody bound to IgV domain of human TIM-3== | |
| - | + | <StructureSection load='8tft' size='340' side='right'caption='[[8tft]], [[Resolution|resolution]] 2.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8tft]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8TFT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8TFT FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8tft FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8tft OCA], [https://pdbe.org/8tft PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8tft RCSB], [https://www.ebi.ac.uk/pdbsum/8tft PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8tft ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: Oganesyan | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/HAVR2_HUMAN HAVR2_HUMAN] Regulates macrophage activation. Inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. May be also involved in T-cell homing. Receptor for LGALS9.<ref>PMID:14556005</ref> <ref>PMID:16286920</ref> |
| - | [[Category: | + | == References == |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mazor Y]] | ||
| + | [[Category: Oganesyan VY]] | ||
| + | [[Category: Yang C]] | ||
| + | [[Category: Van Dyk N]] | ||
Current revision
Fab of O13-1 human IgG1 antibody bound to IgV domain of human TIM-3
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