8y55

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Current revision (14:49, 19 February 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8y55 is ON HOLD until Paper Publication
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==Crystal Structure of NAMPT-PF403==
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<StructureSection load='8y55' size='340' side='right'caption='[[8y55]], [[Resolution|resolution]] 1.86&Aring;' scene=''>
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Authors: Yu, S.S., Liu, Y.B., Li, Y.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8y55]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8Y55 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8Y55 FirstGlance]. <br>
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Description: Crystal Structure of NAMPT-PF403
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.86&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1D52:(13~{a}~{S})-6,7-dimethoxy-9,11,12,13,13~{a},14-hexahydrophenanthro[9,10-f]indolizin-3-ol'>A1D52</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
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[[Category: Li, Y]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8y55 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8y55 OCA], [https://pdbe.org/8y55 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8y55 RCSB], [https://www.ebi.ac.uk/pdbsum/8y55 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8y55 ProSAT]</span></td></tr>
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[[Category: Liu, Y.B]]
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</table>
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[[Category: Yu, S.S]]
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== Function ==
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[https://www.uniprot.org/uniprot/NAMPT_HUMAN NAMPT_HUMAN] Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway (By similarity).
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Li Y]]
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[[Category: Liu YB]]
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[[Category: Yu SS]]

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Crystal Structure of NAMPT-PF403

PDB ID 8y55

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