8z0t
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of the human ige-fc bound to its high affinity receptor fc(epsilon)== | |
| - | + | <StructureSection load='8z0t' size='340' side='right'caption='[[8z0t]], [[Resolution|resolution]] 3.58Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8z0t]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8Z0T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8Z0T FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.58Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> |
| - | [[Category: Deng | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8z0t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8z0t OCA], [https://pdbe.org/8z0t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8z0t RCSB], [https://www.ebi.ac.uk/pdbsum/8z0t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8z0t ProSAT]</span></td></tr> |
| - | [[Category: Du | + | </table> |
| - | [[Category: Xiao | + | == Function == |
| + | [https://www.uniprot.org/uniprot/FCERA_HUMAN FCERA_HUMAN] Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Deng MJ]] | ||
| + | [[Category: Du S]] | ||
| + | [[Category: Xiao JY]] | ||
Current revision
Structure of the human ige-fc bound to its high affinity receptor fc(epsilon)
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Categories: Homo sapiens | Large Structures | Deng MJ | Du S | Xiao JY
