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1sij

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[[Image:1sij.gif|left|200px]]
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{{STRUCTURE_1sij| PDB=1sij | SCENE= }}
{{STRUCTURE_1sij| PDB=1sij | SCENE= }}
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'''Crystal structure of the Aldehyde Dehydrogenase (a.k.a. AOR or MOP) of Desulfovibrio gigas covalently bound to [AsO3]-'''
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===Crystal structure of the Aldehyde Dehydrogenase (a.k.a. AOR or MOP) of Desulfovibrio gigas covalently bound to [AsO3]-===
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==Overview==
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X-ray crystallography has been used to determine the structure of arsenite-inhibited aldehyde dehydrogenase from Desulfovibrio gigas, a member of the xanthine oxidase family of mononuclear molybdenum enzymes. The structure shows an AsO3 moiety bound to the molybdenum atom of the active site through one of the oxygen atoms. A reduced sample of arsenite-inhibited aldehyde dehydrogenase has a Mo(V) signal that shows anisotropic hyperfine and quadrupole coupling to one arsenic atom. This signal has a strong resemblance with a previously reported signal for arsenite-inhibited xanthine oxidase.
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(as it appears on PubMed at http://www.pubmed.gov), where 15250689 is the PubMed ID number.
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{{ABSTRACT_PUBMED_15250689}}
==About this Structure==
==About this Structure==
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[[Category: Arsenite inhibition]]
[[Category: Arsenite inhibition]]
[[Category: Xanthine oxidase family]]
[[Category: Xanthine oxidase family]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 08:44:47 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 15:33:53 2008''

Revision as of 12:33, 27 July 2008

Image:1sij.png

Template:STRUCTURE 1sij

Crystal structure of the Aldehyde Dehydrogenase (a.k.a. AOR or MOP) of Desulfovibrio gigas covalently bound to [AsO3]-

Template:ABSTRACT PUBMED 15250689

About this Structure

1SIJ is a Single protein structure of sequence from Desulfovibrio gigas. Full crystallographic information is available from OCA.

Reference

X-ray crystal structure and EPR spectra of "arsenite-inhibited" Desulfovibriogigas aldehyde dehydrogenase: a member of the xanthine oxidase family., Boer DR, Thapper A, Brondino CD, Romao MJ, Moura JJ, J Am Chem Soc. 2004 Jul 21;126(28):8614-5. PMID:15250689

Page seeded by OCA on Sun Jul 27 15:33:53 2008

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