1sjm

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[[Image:1sjm.gif|left|200px]]
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{{STRUCTURE_1sjm| PDB=1sjm | SCENE= }}
{{STRUCTURE_1sjm| PDB=1sjm | SCENE= }}
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'''Nitrite bound copper containing nitrite reductase'''
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===Nitrite bound copper containing nitrite reductase===
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==Overview==
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A copper-nitrosyl intermediate forms during the catalytic cycle of nitrite reductase, the enzyme that mediates the committed step in bacterial denitrification. The crystal structure of a type 2 copper-nitrosyl complex of nitrite reductase reveals an unprecedented side-on binding mode in which the nitrogen and oxygen atoms are nearly equidistant from the copper cofactor. Comparison of this structure with a refined nitrite-bound crystal structure explains how coordination can change between copper-oxygen and copper-nitrogen during catalysis. The side-on copper-nitrosyl in nitrite reductase expands the possibilities for nitric oxide interactions in copper proteins such as superoxide dismutase and prions.
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(as it appears on PubMed at http://www.pubmed.gov), where 15131305 is the PubMed ID number.
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{{ABSTRACT_PUBMED_15131305}}
==About this Structure==
==About this Structure==
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[[Category: Copper]]
[[Category: Copper]]
[[Category: Nitrite]]
[[Category: Nitrite]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 08:47:10 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 11:33:25 2008''

Revision as of 08:33, 29 July 2008

Image:1sjm.png

Template:STRUCTURE 1sjm

Nitrite bound copper containing nitrite reductase

Template:ABSTRACT PUBMED 15131305

About this Structure

1SJM is a Single protein structure of sequence from Alcaligenes faecalis. Full crystallographic information is available from OCA.

Reference

Side-on copper-nitrosyl coordination by nitrite reductase., Tocheva EI, Rosell FI, Mauk AG, Murphy ME, Science. 2004 May 7;304(5672):867-70. PMID:15131305

Page seeded by OCA on Tue Jul 29 11:33:25 2008

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