9f6k

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Current revision (05:46, 7 August 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 9f6k is ON HOLD until Paper Publication
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==Human DNA Polymerase epsilon bound to T-C mismatched DNA (Frayed Substrate state)==
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<StructureSection load='9f6k' size='340' side='right'caption='[[9f6k]], [[Resolution|resolution]] 4.20&Aring;' scene=''>
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Authors: Roske, J.J., Yeeles, J.T.P.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[9f6k]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9F6K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9F6K FirstGlance]. <br>
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Description: Human DNA Polymerase epsilon bound to T-C mismatched DNA (Frayed Substrate state)
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.2&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
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[[Category: Yeeles, J.T.P]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9f6k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9f6k OCA], [https://pdbe.org/9f6k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9f6k RCSB], [https://www.ebi.ac.uk/pdbsum/9f6k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9f6k ProSAT]</span></td></tr>
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[[Category: Roske, J.J]]
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</table>
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== Disease ==
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[https://www.uniprot.org/uniprot/DPOE1_HUMAN DPOE1_HUMAN] Facial dysmorphism - immunodeficiency - livedo - short stature. Disease susceptibility is associated with variations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry.
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== Function ==
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[https://www.uniprot.org/uniprot/DPOE1_HUMAN DPOE1_HUMAN] Participates in DNA repair and in chromosomal DNA replication.
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Roske JJ]]
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[[Category: Yeeles JTP]]

Current revision

Human DNA Polymerase epsilon bound to T-C mismatched DNA (Frayed Substrate state)

PDB ID 9f6k

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