9bof
From Proteopedia
(Difference between revisions)
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- | '''Unreleased structure''' | ||
- | + | ==16E10 Fab bound to norovirus GI.1 P domain== | |
- | + | <StructureSection load='9bof' size='340' side='right'caption='[[9bof]], [[Resolution|resolution]] 2.61Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[9bof]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Norovirus Norovirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9BOF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9BOF FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.61Å</td></tr> | |
- | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9bof FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9bof OCA], [https://pdbe.org/9bof PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9bof RCSB], [https://www.ebi.ac.uk/pdbsum/9bof PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9bof ProSAT]</span></td></tr> |
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/CAPSD_NVN68 CAPSD_NVN68] Capsid protein self assembles to form an icosahedral capsid with a T=3 symmetry, about 38 nm in diameter, and consisting of 180 capsid proteins. A smaller form of capsid with a diameter of 23 nm might be capsid proteins assembled as icosahedron with T=1 symmetry. The capsid encapsulate the genomic RNA and VP2 proteins. Attaches virion to target cells by binding histo-blood group antigens present on gastroduodenal epithelial cells.<ref>PMID:16840313</ref> Soluble capsid protein may play a role in viral immunoevasion.<ref>PMID:16840313</ref> | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Homo sapiens]] | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Norovirus]] | ||
+ | [[Category: Kwong PD]] | ||
+ | [[Category: Morano NC]] | ||
+ | [[Category: Olia AS]] | ||
+ | [[Category: Shapiro L]] |
Current revision
16E10 Fab bound to norovirus GI.1 P domain
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Categories: Homo sapiens | Large Structures | Norovirus | Kwong PD | Morano NC | Olia AS | Shapiro L