DNA polymerase 3D structures

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Line 6: Line 6:
**[[1taq]] – TaDpo I - ''Thermus aquaticus''<br />
**[[1taq]] – TaDpo I - ''Thermus aquaticus''<br />
-
**[[1jxe]] – TaDpo I Stoffel fragment 290-832<br />
+
**[[1jxe]], [[8xjr]] – TaDpo I Stoffel fragment 290-832<br />
**[[5ktq]] – TaDpo I Stoffel fragment + nucleotide<br />
**[[5ktq]] – TaDpo I Stoffel fragment + nucleotide<br />
-
**[[5szt]], [[5e41]], [[6q4v]], [[6q4u]], [[6fbi]], [[6fbh]], [[6fbg]], [[6fbf]], [[6fbe]], [[6fbd]], [[6fbc]], [[5z3n]], [[5yth]], [[5ytg]], [[5ytf]], [[5yte]], [[5ytd]], [[5ytc]], [[5w6k]], [[5w6q]] – TaDpo I Stoffel fragment + DNA + nucleotide derivative<br />
+
**[[5szt]], [[5e41]], [[6q4v]], [[6q4u]], [[6fbi]], [[6fbh]], [[6fbg]], [[6fbf]], [[6fbe]], [[6fbd]], [[6fbc]], [[5z3n]], [[5yth]], [[5ytg]], [[5ytf]], [[5yte]], [[5ytd]], [[5ytc]], [[5w6k]], [[5w6q]], [[8xk7]], [[9fm3]] – TaDpo I Stoffel fragment + DNA + nucleotide derivative<br />
**[[5nkl]] – TaDpo I + DNA + pyridine derivative + pyrrol derivative<br />
**[[5nkl]] – TaDpo I + DNA + pyridine derivative + pyrrol derivative<br />
**[[5o7t]] – TaDpo I (mutant) + DNA + CTP derivative<br />
**[[5o7t]] – TaDpo I (mutant) + DNA + CTP derivative<br />
Line 17: Line 17:
**[[6dsy]], [[6dsx]], [[6dsw]], [[6dsv]], [[6dsu]], [[7k5o]], [[7k5p]], [[7k5r]], [[7k5q]], [[7k5s]], [[7k5t]], [[7k5u]] - GsDpo I + DNA - ''Geobacillus stearothermophilus''<br />
**[[6dsy]], [[6dsx]], [[6dsw]], [[6dsv]], [[6dsu]], [[7k5o]], [[7k5p]], [[7k5r]], [[7k5q]], [[7k5s]], [[7k5t]], [[7k5u]] - GsDpo I + DNA - ''Geobacillus stearothermophilus''<br />
**[[3eyz]], [[6p5c]] - GsDpo I (mutant) + DNA <br />
**[[3eyz]], [[6p5c]] - GsDpo I (mutant) + DNA <br />
-
**[[6mu5]], [[6mu4]], [[6ur2]], [[6ur4]] - GsDpo I + DNA + nucleotide derivative <br />
+
**[[6mu5]], [[6mu4]], [[6ur2]], [[6ur4]], [[8sck]] - GsDpo I + DNA + nucleotide derivative <br />
-
**[[3ez5]], [[6ueu]], [[6ur9]], [[6us5]] - GsDpo I (mutant) + DNA + nucleotide <br />
+
**[[3ez5]], [[6ueu]], [[6ur9]], [[6us5]], [[8scg]], [[8sci]], [[8scj]], [[8scl]], [[8scm]], [[8scn]], [[8sco]], [[8scp]], [[8scq]], [[8scr]], [[8scs]], [[8sct]], [[8scu]] - GsDpo I (mutant) + DNA + nucleotide <br />
-
**[[3pv8]], [[3px0]], [[3px4]], [[3px6]], [[4dqi]], [[4dqp]], [[4dqq]], [[4dqr]], [[4dqs]], [[4ds4]], [[4ds5]], [[4dse]], [[4dsf]], [[4e0d]], [[4ez6]], [[4ez9]], [[4f2r]], [[4f2s]], [[4f3o]], [[4f4k]], [[4f8r]] - GkDpo I (mutant) + DNA – ''Geobacillus kaustophilus''<br />
+
**[[3pv8]], [[3px0]], [[3px4]], [[3px6]], [[4dqi]], [[4dqp]], [[4dqq]], [[4dqr]], [[4dqs]], [[4ds4]], [[4ds5]], [[4dse]], [[4dsf]], [[4e0d]], [[4ez6]], [[4ez9]], [[4f2r]], [[4f2s]], [[4f3o]], [[4f4k]], [[4f8r]] - GkDpo I (mutant) + DNA – ''Geobacillus kaustophilus<''br />
-
**[[6vdc]], [[6vde]] – MsPol I – ''Mycobacterium smegmatis''<br />
+
**[[6vdc]], [[6vde]] – MsDpo I – ''Mycobacterium smegmatis''<br />
**[[6vdd]] - MsDpo I + DNA + nucleotide derivative <br />
**[[6vdd]] - MsDpo I + DNA + nucleotide derivative <br />
-
**[[7pbk]] – Dpo I – Vibrio phage<br />
 
-
**[[7r0k]] – Dpo I – Thermus phage<br />
 
*DNA polymerase I klenow fragment or Taq polymerase
*DNA polymerase I klenow fragment or Taq polymerase
Line 29: Line 27:
**[[2kzz]], [[1d8y]], [[2kzm]] – EcDpo I - ''Escherichia coli''<br />
**[[2kzz]], [[1d8y]], [[2kzm]] – EcDpo I - ''Escherichia coli''<br />
**[[1qsl]] - EcDpo I + DNA<br />
**[[1qsl]] - EcDpo I + DNA<br />
 +
**[[8oo6]], [[8ooy]] - EcDpo I + DNA – Cryo EM<br />
**[[1kfs]], [[1krp]], [[1ksp]], [[1kln]] - EcDpo I (mutant) + DNA<br />
**[[1kfs]], [[1krp]], [[1ksp]], [[1kln]] - EcDpo I (mutant) + DNA<br />
**[[1kfd]], [[1dpi]] - EcDpo I + nucleotide<br />
**[[1kfd]], [[1dpi]] - EcDpo I + nucleotide<br />
Line 37: Line 36:
**[[4bwm]], [[4bwj]] - TaDpo I + DNA + RNA<br />
**[[4bwm]], [[4bwj]] - TaDpo I + DNA + RNA<br />
**[[3py8]] - TaDpo I (mutant) + DNA<br />
**[[3py8]] - TaDpo I (mutant) + DNA<br />
-
**[[3m8r]], [[3m8s]], [[3lwl]], [[3lwm]], [[1qss]], [[1qsy]], [[1qtm]], [[2ktq]], [[3ktq]], [[4ktq]], [[3rr7]], [[3rr8]], [[3rrg]], [[3rrh]], [[3t3f]], [[4df4]], [[4df8]], [[4dfj]], [[4dfk]], [[4dfm]], [[4dfp]], [[7owf]] - TaDpo I + DNA + nucleotide<br />
+
**[[3m8r]], [[3m8s]], [[3lwl]], [[3lwm]], [[1qss]], [[1qsy]], [[1qtm]], [[2ktq]], [[3ktq]], [[4ktq]], [[3rr7]], [[3rr8]], [[3rrg]], [[3rrh]], [[3t3f]], [[4df4]], [[4df8]], [[4dfj]], [[4dfk]], [[4dfm]], [[4dfp]], [[7owf]], [[9fmf]] - TaDpo I + DNA + nucleotide<br />
**[[3rrg]], [[4n56]], [[4n5s]], [[4xiu]] - TaDpo I (mutant) + DNA + nucleotide<br />
**[[3rrg]], [[4n56]], [[4n5s]], [[4xiu]] - TaDpo I (mutant) + DNA + nucleotide<br />
**[[1xwl]] - GsDpo I <br />
**[[1xwl]] - GsDpo I <br />
-
**[[2xo7]], [[3hp6]], [[3hpo]], [[2hhq]], [[2hhs]], [[2hht]], [[2hhu]], [[2hhv]], [[2hhw]], [[2hhx]], [[2hvh]], [[2hvi]], [[2hw3]], [[1xc9]], [[1ua0]], [[1ua1]], [[1njw]], [[1njx]], [[1njy]], [[1njz]], [[1nk0]], [[1nk4]], [[1nk5]], [[1nk6]], [[1nk7]], [[1nk8]], [[1nk9]], [[1nkb]], [[1nkc]], [[1nke]], [[1l3s]], [[2bdp]], [[4bdp]], [[2xy5]], [[2xy6]], [[2xy7]], [[2y1i]], [[2y1j]], [[3tan]], [[3tap]], [[3taq]], [[3tar]], [[3thv]], [[4b9l]], [[4b9m]], [[4b9n]], [[4b9s]], [[4b9t]], [[4b9u]], [[4b9v]] - GsDpo I + DNA<br />
+
**[[1l3s]], [[1njw]], [[1njx]], [[1njy]], [[1njz]], [[1nk0]], [[1nk4]], [[1nk5]], [[1nk6]], [[1nk7]], [[1nk8]], [[1nk9]], [[1nkb]], [[1nkc]], [[1nke]], [[1ua0]], [[1ua1]], [[1xc9]], [[2bdp]], [[2hhq]], [[2hhs]], [[2hht]], [[2hhu]], [[2hhv]], [[2hhw]], [[2hhx]], [[2hvh]], [[2hvi]], [[2hw3]], [[2xo7]], [[2xy5]], [[2xy6]], [[2xy7]], [[2y1i]], [[2y1j]], [[3hp6]], [[3hpo]], [[3tan]], [[3tap]], [[3taq]], [[3tar]], [[3thv]], [[4b9l]], [[4b9m]], [[4b9n]], [[4b9s]], [[4b9t]], [[4b9u]], [[4b9v]], [[4bdp]] - GsDpo I + DNA<br />
**[[4dsi]], [[4dsj]], [[4dsk]], [[4dsl]], [[4dwi]] - GsDpo I (mutant) + DNA<br />
**[[4dsi]], [[4dsj]], [[4dsk]], [[4dsl]], [[4dwi]] - GsDpo I (mutant) + DNA<br />
**[[3ht3]], [[1u45]], [[1u47]], [[1u48]], [[1u49]], [[1u4b]], [[1l3t]], [[1l3u]], [[1l3v]], [[1l5u]], [[1lv5]], [[3bdp]], [[3ti0]], [[4o0i]], [[4uqg]] - GsDpo I + DNA + nucleotide<br />
**[[3ht3]], [[1u45]], [[1u47]], [[1u48]], [[1u49]], [[1u4b]], [[1l3t]], [[1l3u]], [[1l3v]], [[1l5u]], [[1lv5]], [[3bdp]], [[3ti0]], [[4o0i]], [[4uqg]] - GsDpo I + DNA + nucleotide<br />
 +
**[[8jrb]] - Dpo I – ''Aquifex pyrophilus''<br />
*DNA polymerase II
*DNA polymerase II
Line 49: Line 49:
**[[3k5n]] - EcDpo II (mutant) + DNA<br />
**[[3k5n]] - EcDpo II (mutant) + DNA<br />
**[[3k5o]], [[1q8i]] - EcDpo II (mutant) <br />
**[[3k5o]], [[1q8i]] - EcDpo II (mutant) <br />
-
**[[3o59]], [[5bkh]] - PhDpo II large subunit - ''Pyrococcus horikoshii<''br />
+
**[[3o59]], [[5bkh]] - PhDpo II large subunit - ''Pyrococcus horikoshii''<br />
**[[2kxe]] - PhDpo II small subunit<br />
**[[2kxe]] - PhDpo II small subunit<br />
**[[1qqc]] – DeDpo II – ''Desulfurococcus''<br />
**[[1qqc]] – DeDpo II – ''Desulfurococcus''<br />
Line 55: Line 55:
**[[5ihe]] - PaDpo II small subunit <br />
**[[5ihe]] - PaDpo II small subunit <br />
**[[6hmf]] - PaDpo II small subunit (mutant)<br />
**[[6hmf]] - PaDpo II small subunit (mutant)<br />
 +
**[[8ppu]] - PaDpo II small subunit + PCNA + DNA + nucleotide – Cryo EM<br />
 +
**[[8ppt]], [[8ppv]] - PaDpo II small subunit (mutant) + PCNA + DP2 + DNA + nucleotide – Cryo EM<br />
 +
**[[9f29]], [[9f2a]] - PaDpo II small subunit + RPA32 – Cryo EM<br />
**[[6hms]] - PaDpo II small+large subunits + DNA – Cryo EM <br />
**[[6hms]] - PaDpo II small+large subunits + DNA – Cryo EM <br />
**[[6knb]], [[6knc]] - TkPol II small+large subunits + PCNA + DNA - ''Thermococcus kodakarensis'' – Cryo EM <br />
**[[6knb]], [[6knc]] - TkPol II small+large subunits + PCNA + DNA - ''Thermococcus kodakarensis'' – Cryo EM <br />
Line 63: Line 66:
*DNA polymerase III subunit alpha
*DNA polymerase III subunit alpha
-
**[[2hnh]], [[2hqa]] - EcDpo III subunit alpha catalytic fragment<br />
+
**[[2hnh]], [[2hqa]] - EcDpo III subunit catalytic fragment<br />
-
**[[4jom]] - EcDpo III alpha subunit catalytic fragment (mutant)<br />
+
**[[4jom]] - EcDpo III subunit catalytic fragment (mutant)<br />
-
**[[5m1s]], [[5fkw]], [[5fkv]], [[5fku]] - EcDpo III alpha (mutant) beta, epsilon subunits + DNA – Cryo EM<br />
+
**[[5m1s]], [[5fkw]], [[5fkv]], [[5fku]] - EcDpo III (mutant) subunits + DNA – Cryo EM<br />
**[[1ok7]] - EcDpo III residues 1-366 + EcDpo IV C-terminal<br />
**[[1ok7]] - EcDpo III residues 1-366 + EcDpo IV C-terminal<br />
-
**[[2hpi]], [[2hpm]] - TaDpo III alpha subunit<br />
+
**[[2hpi]], [[2hpm]] - TaDpo III subunit<br />
-
**[[3e0d]] - TaDpo III alpha subunit + DNA<br />
+
**[[3e0d]] - TaDpo III subunit + DNA<br />
-
**[[3f2b]], [[3f2c]], [[3f2d]], [[4iqj]] – GkDpo III alpha subunit + DNA + nucleotide <br />
+
**[[3f2b]], [[3f2c]], [[3f2d]], [[4iqj]] – GkDpo III subunit + DNA + nucleotide <br />
-
**[[1zd7]], [[1zde]], [[3nzm]], [[5ol5]], [[5ol1]] - SyDpo III alpha subunit – Synechocystis<br />
+
**[[1zd7]], [[1zde]], [[3nzm]], [[5ol5]], [[5ol1]] - SyDpo III subunit – ''Synechocystis''<br />
-
**[[4gig]] - SyDpo III alpha subunit (mutant) <br />
+
**[[4gig]] - SyDpo III subunit (mutant) <br />
-
**[[2keq]], [[4kl5]], [[4kl6]] - NpDpo III alpha subunit – Nostoc punctiforme<br />
+
**[[2keq]], [[4kl5]], [[4kl6]] - NpDpo III subunit – ''Nostoc punctiforme''<br />
-
**[[4lx3]], [[4qfq]] - NpDpo III alpha subunit + nucleic acid binding tRNA/helicase<br />
+
**[[4lx3]], [[4qfq]] - NpDpo III subunit + nucleic acid binding tRNA/helicase<br />
-
**[[5lew]] - MtPol III alpha subunit – Mycobacterrium tuberculosis<br />
+
**[[5lew]] - MtPol III subunit – ''Mycobacterrium tuberculosis''<br />
-
**[[7pu7]] - MtDpo III alpha subunit + DNA<br />
+
**[[7pu7]] - MtDpo III subunit + DNA<br />
*DNA polymerase III subunit beta or sliding clamp
*DNA polymerase III subunit beta or sliding clamp
-
**[[1mmi]], [[2pol]], [[4k3s]], [[4pnv]], [[4pnw]] - EcDpo III subunit beta<br />
+
**[[1mmi]], [[2pol]], [[4k3s]], [[4pnv]], [[4pnw]] - EcDpo III subunit <br />
-
**[[2xur]], [[3f1v]], [[3pwe]] - EcDpo III subunit beta (mutant) <br />
+
**[[2xur]], [[3f1v]], [[3pwe]] - EcDpo III subunit (mutant) <br />
-
**[[3d1e]] - EcDpo III subunit beta + EcDpo II C-terminal<br />
+
**[[3d1e]] - EcDpo III subunit + EcDpo II C-terminal<br />
-
**[[1unn]] - EcDpo III subunit beta + EcDpo IV little finger<br />
+
**[[1unn]] - EcDpo III subunit + EcDpo IV little finger<br />
-
**[[2avt]] - Dpo III beta subunit – ''Streptococcus pyogenes''<br />
+
**[[8ciz]] - EcDpo III subunit  + peptide antibiotic <br />
-
**[[2awa]] - Dpo III beta subunit – ''Streptococcus pneumoniae''<br />
+
**[[8pat]], [[8pay]] - EcDpo III subunit  + peptide <br />
-
**[[4trt]] – DrDpo III beta subunit – ''Deinococcus radiodurans''<br />
+
**[[8cix]], [[8ciy]] - EcDpo III subunit  + inhibitor<br />
 +
**[[2avt]] - Dpo III subunit – ''Streptococcus pyogenes''<br />
 +
**[[2awa]] - Dpo III subunit – ''Streptococcus pneumoniae''<br />
 +
**[[4trt]] – DrDpo III subunit – ''Deinococcus radiodurans''<br />
**[[2p1j]] – TmDpo III exonuclease domain – ''Thermotoga maritima''<br />
**[[2p1j]] – TmDpo III exonuclease domain – ''Thermotoga maritima''<br />
-
**[[1vpk]] - TmDpo III beta subunit<br />
+
**[[1vpk]] - TmDpo III subunit<br />
-
**[[3t0p]] - Dpo III beta subunit – ''Eubacterium rectale''<br />
+
**[[3t0p]] - Dpo III subunit – ''Eubacterium rectale''<br />
-
**[[6ap4]] - Dpo III beta subunit – ''Acinetobacter baumannii''<br />
+
**[[6ap4]] - Dpo III subunit – ''Acinetobacter baumannii''<br />
-
**[[6amq]] - Dpo III beta subunit – ''Enterobacter cloacae''<br />
+
**[[6amq]] - Dpo III subunit – ''Enterobacter cloacae''<br />
-
**[[5wce]], [[6izo]], [[6jir]] - Dpo III beta subunit – ''Caulobacter crescentus''<br />
+
**[[5wyp]], [[5wce]], [[6izo]], [[6jir]] - Dpo III subunit – ''Caulobacter crescentus''<br />
-
**[[5w7z]] - RcDpo III beta subunit – ''Rickettsia conorii''<br />
+
**[[5w7z]] - RcDpo III subunit – ''Rickettsia conorii''<br />
-
**[[6man]] - Dpo III beta subunit – ''Rickettsia bellii''<br />
+
**[[6man]] - Dpo III subunit – ''Rickettsia bellii''<br />
-
**[[6d46]] - RtDpo III beta subunit – ''Rickettsia typhi''<br />
+
**[[6d46]] - RtDpo III subunit – ''Rickettsia typhi''<br />
-
**[[6dlk]] - RrDpo III beta subunit – ''Rickettsia rickettsii''<br />
+
**[[6dlk]] - RrDpo III subunit – ''Rickettsia rickettsii''<br />
-
**[[6d47]] - MmDpo III beta subunit – ''Mycobacterium marinum''<br />
+
**[[6d47]] - MmDpo III subunit – ''Mycobacterium marinum''<br />
-
**[[1jqj]], [[1jql]] - EcDpo III subunit beta,delta(mutant) <br />
+
**[[1jqj]], [[1jql]] - EcDpo III subunit (mutant) <br />
-
**[[4tr6]] - Pol III beta subunit – Bacillus subtilis<br />
+
**[[4tr6]] - Pol III subunit – Bacillus subtilis<br />
-
**[[3p16]], [[3rb9]], [[4tr7]] - MtPol III beta subunit <br />
+
**[[3p16]], [[3rb9]], [[4tr7]] - MtPol III subunit <br />
-
**[[4tr8]], [[6ams]] - PsaPol III beta subunit –'' Pseudomonas aeruginosa''<br />
+
**[[4tr8]], [[6ams]] - PsaPol III subunit – ''Pseudomonas aeruginosa''<br />
-
**[[6pth]] - PsaPol III beta subunit + griselimycin<br />
+
**[[6pth]] - PsaPol III subunit + griselimycin<br />
-
**[[4s3i]], [[4rki]] - HpPol III beta subunit – ''Helicobacter pylori''<br />
+
**[[4s3i]], [[4rki]] - HpPol III subunit – ''Helicobacter pylori''<br />
-
**[[6aig]] - Dpo III beta subunit – ''Aeropyrum pernix''<br />
+
**[[6aig]] - Dpo III subunit – ''Aeropyrum pernix''<br />
-
**[[6deg]] - BbDpo III beta subunit – ''Bartonella birtlesii''<br />
+
**[[6deg]] - BbDpo III subunit – ''Bartonella birtlesii''<br />
-
**[[7rzm]] - Dpo III beta subunit – ''Stenotrophomonas maltophilia''<br />
+
**[[7rzm]] - Dpo III subunit – ''Stenotrophomonas maltophilia''<br />
-
**[[8dt6]] - Dpo III beta subunit – ''Elizabethkingia anophelis''<br />
+
**[[8dt6]] - Dpo III subunit – ''Elizabethkingia anophelis''<br />
*DNA polymerase III subunit beta or sliding clamp complex
*DNA polymerase III subunit beta or sliding clamp complex
-
**[[3d1g]], [[3qsb]], [[4k3k]], [[4k3l]], [[4mjp]], [[4mjq]], [[4mjr]], [[4n94]], [[4n95]], [[4n96]], [[4n97]], [[4n98]], [[4n99]], [[4n9a]], [[4ovf]], [[4ovg]], [[4ovh]], [[4pnu ]] - EcDpo III subunit beta + inhibitor<br />
+
**[[3d1g]], [[3qsb]], [[4k3k]], [[4k3l]], [[4mjp]], [[4mjq]], [[4mjr]], [[4n94]], [[4n95]], [[4n96]], [[4n97]], [[4n98]], [[4n99]], [[4n9a]], [[4ovf]], [[4ovg]], [[4ovh]], [[4pnu ]] - EcDpo III subunit + inhibitor<br />
-
**[[3bep]] - EcDpo III subunit beta + DNA<br />
+
**[[3bep]] - EcDpo III subunit + DNA<br />
-
**[[5x06]] - EcDpo III subunit beta + DnaA regulatory inactivator<br />
+
**[[5x06]] - EcDpo III subunit + DnaA regulatory inactivator<br />
-
**[[3d1f]], [[3q4j]], [[3q4k]], [[3q4l]], [[4k3l]], [[4k3m]], [[4k3o]], [[4k3p]], [[4k3q]], [[4k3r]], [[4k74]], [[6fvl]], [[7az5]], [[7az6]], [[7az7]], [[7az8]], [[7azc]], [[7azd]], [[7aze]], [[7azf]], [[7azg]], [[7azk]], [[7azl]] - EcDpo III beta subunit + polypeptide<br />
+
**[[3d1f]], [[3q4j]], [[3q4k]], [[3q4l]], [[4k3l]], [[4k3m]], [[4k3o]], [[4k3p]], [[4k3q]], [[4k3r]], [[4k74]], [[6fvl]], [[7az5]], [[7az6]], [[7az7]], [[7az8]], [[7azc]], [[7azd]], [[7aze]], [[7azf]], [[7azg]], [[7azk]], [[7azl]] - EcDpo III subunit + polypeptide<br />
-
**[[6fvm]] - EcDpo III beta subunit (mutant) + P7 peptide<br />
+
**[[6fvm]] - EcDpo III subunit (mutant) + P7 peptide<br />
-
**[[5g4q]], [[5g48]], [[5fxt]], [[5fve]] - HpPol III beta subunit + NSAID drug <br />
+
**[[5g4q]], [[5g48]], [[5fxt]], [[5fve]] - HpPol III subunit + NSAID drug <br />
-
**[[5frq]] - HpPol III beta subunit + DNA ligase peptide<br />
+
**[[5frq]] - HpPol III subunit + DNA ligase peptide<br />
-
**[[5dai]] - TkPol III beta subunit + FEN-1 peptide <br />
+
**[[5dai]] - TkPol III subunit + FEN-1 peptide <br />
-
**[[5ah4]], [[5ah2]], [[5agv]], [[5agu]] – MsPol III beta subunit + gricelimycin <br />
+
**[[5ah4]], [[5ah2]], [[5agv]], [[5agu]] – MsPol III subunit + gricelimycin <br />
-
**[[6drt]] – T4Dpo III beta subunit + polypeptide - Enterobacteria phage T4<br />
+
**[[6drt]] – T4Dpo III subunit + polypeptide - Enterobacteria phage T4<br />
-
**[[6dj8]] – Dpo III beta subunit + polypeptide – ''Borrelia burgdorferi''<br />
+
**[[6dj8]] – Dpo III subunit + polypeptide – ''Borrelia burgdorferi''<br />
-
**[[6fvo]], [[6fvn]] - MtPol III beta subunit + P7 peptide<br />
+
**[[6fvo]], [[6fvn]] - MtPol III subunit + P7 peptide<br />
-
**[[6t7x]] - PaPol III beta subunit <br />
+
**[[6t7x]] - PaPol III subunit <br />
-
**[[4tsz]], [[6t7y]] - PaPol III beta subunit + peptide<br />
+
**[[4tsz]], [[6t7y]] - PaPol III subunit + peptide<br />
-
**[[6t8h]] - PaPol III beta subunit + Dol II small subunit + DP2 – Cryo EM<br />
+
**[[6t8h]] - PaPol III subunit + Dol II small subunit + DP2 – Cryo EM<br />
-
**[[6djk]] - RtDpo III beta subunit + polypeptide <br />
+
**[[6djk]] - RtDpo III subunit + polypeptide <br />
-
**[[6dm6]] - RcPol III beta subunit + peptide<br />
+
**[[6dm6]] - RcPol III subunit + peptide<br />
-
**[[6dly]] - MmPol III beta subunit + peptide<br />
+
**[[6dly]] - MmPol III subunit + peptide<br />
-
**[[6ptv]] - RrPol III beta subunit + griselimycin<br />
+
**[[6ptv]] - RrPol III subunit + griselimycin<br />
-
**[[6ptr]] - BbPol III beta subunit + griselimycin<br />
+
**[[6ptr]] - BbPol III subunit + griselimycin<br />
 +
**[[8djq]], [[8dk9]] - Pol III  subunit + peptide – ''Mycolicibacterium thermoresistibile''<br />
*DNA polymerase III subunit gamma
*DNA polymerase III subunit gamma
-
**[[5c51]], [[5c52]], [[5c53]] - hDpo III gamma subunit + DNA + nucleotide<br />
+
**[[5c51]], [[5c52]], [[5c53]] - hDpo III subunit + DNA + nucleotide<br />
-
**[[1njf]], [[1njg]] - EcDpo III subunit gamma N-terminal domains 1-2<br />
+
**[[1njf]], [[1njg]] - EcDpo III subunit  N-terminal domains 1-2<br />
-
**[[2gno]] - TmDpo III gamma subunit<br />
+
**[[2gno]] - TmDpo III subunit<br />
-
**[[1xxh]], [[1jr3]] - EcDpo III subunit gamma, delta,delta’ <br />
+
**[[1xxh]], [[1jr3]] - EcDpo III subunit ’ <br />
-
**[[1xxi]] - EcDpo III subunit gamma, delta,delta’ + nucleotide<br />
+
**[[1xxi]] - EcDpo III subunit ’ + nucleotide<br />
*DNA polymerase III subunit delta
*DNA polymerase III subunit delta
-
**[[1jqj]], [[1jql]] - EcDpo III subunit beta,delta(mutant) <br />
+
**[[1jqj]], [[1jql]] - EcDpo III subunit (mutant) <br />
-
**[[1a5t]] - EcDpo III subunit delta’ <br />
+
**[[1a5t]] - EcDpo III subunit ’ <br />
-
**[[1xxh]], [[1jr3]] - EcDpo III subunit gamma, delta,delta’ <br />
+
**[[1xxh]], [[1jr3]] - EcDpo III subunit ’ <br />
-
**[[1xxi]] - EcDpo III subunit gamma, delta,delta’ + nucleotide<br />
+
**[[1xxi]] - EcDpo III subunit ’ + nucleotide<br />
-
**[[3glh]] - EcDpo III subunit delta,delta’,tau<br />
+
**[[3glh]] - EcDpo III subunit ’<br />
-
**[[3glf]] - EcDpo III subunitdelta,delta’,tau + DNA<br />
+
**[[3glf]] - EcDpo III subunit ’ DNA<br />
-
**[[3gli]] - EcDpo III subunit delta,delta’,tau, zeta + DNA<br />
+
**[[3gli]] - EcDpo III subunit ’ DNA<br />
-
**[[3glg]] - EcDpo III subunit delta,delta’,tau(mutant) + DNA<br />
+
**[[3glg]] - EcDpo III subunit ’mutant DNA<br />
*DNA polymerase III subunit epsilon
*DNA polymerase III subunit epsilon
-
**[[2gui]] – EcDpo III subunit epsilon N-terminal<br />
+
**[[2gui]] – EcDpo III subunit N-terminal<br />
-
**[[1j53]], [[1j54]] - EcDpo III subunit epsilon N-terminal exonuclease domain<br />
+
**[[1j53]], [[1j54]] - EcDpo III subunit N-terminal exonuclease domain<br />
-
**[[2ido]] - EcDpo III subunit epsilon+ HOT protein<br />
+
**[[2ido]] - EcDpo III subunit + HOT protein<br />
 +
**[[9f6k]] - EcDpo III subunit + DNA – Cryo EM<br />
 +
**[[9f6d]] - EcDpo III subunit + PCNA + DNA – Cryo EM<br />
**[[4gx8]] - EcDpo III ε subunit/ EcDpo III α subunit<br />
**[[4gx8]] - EcDpo III ε subunit/ EcDpo III α subunit<br />
**[[4gx9]] - EcDpo III ε subunit/ EcDpo III α subunit (mutant)<br />
**[[4gx9]] - EcDpo III ε subunit/ EcDpo III α subunit (mutant)<br />
-
**[[2xy8]] - EcDpo III subunit epsilon, theta<br />
+
**[[2xy8]] - EcDpo III subunit ,<br />
*DNA polymerase III subunit tau
*DNA polymerase III subunit tau
-
**[[2aya]] - EcDpo III subunit tau<br />
+
**[[2aya]] - EcDpo III subunit <br />
-
**[[3glh]] - EcDpo III subunit delta, delta', tau<br />
+
**[[3glh]] - EcDpo III subunit ’<br />
-
**[[3glf]] - EcDpo III subunit delta, delta', tau DNA<br />
+
**[[3glf]] - EcDpo III subunit ’ DNA<br />
-
**[[3glg]] - EcDpo III subunit delta, delta', tau (mutant) + DNA<br />
+
**[[3glg]] - EcDpo III subunit ’mutant DNA<br />
*DNA polymerase III subunit xi
*DNA polymerase III subunit xi
-
**[[3gli]] - EcDpo III subunit delta, delta', tau, xi + DNA<br />
+
**[[3gli]] - EcDpo III subunit ’ DNA<br />
*DNA polymerase III subunit theta
*DNA polymerase III subunit theta
-
**[[2axd]], [[2ae9]], [[1du2]] - EcDpo III subunit theta - NMR<br />
+
**[[2axd]], [[2ae9]], [[1du2]] - EcDpo III subunit - NMR<br />
*DNA polymerase III subunit chi+phi
*DNA polymerase III subunit chi+phi
-
**[[1em8]] - EcDpo III subunit chi, phi<br />
+
**[[1em8]] - EcDpo III subunit ,<br />
-
**[[3sxu]] - EcDpo III subunit chi, phi + peptide<br />
+
**[[3sxu]] - EcDpo III subunit ,+ peptide<br />
 +
 
 +
*DNA polymerase III subunit beta+delta+delta’+tau
 +
 
 +
**[[8val]], [[8vam]], [[8van]], [[8vap]], [[8vaq]], [[8var]], [[8vas]], [[8vat]] - EcDpo III + DNA – Cryo EM<br />
 +
 
 +
*DNA polymerase III subunit beta+delta+delta’+tau+psi or clamp loader
 +
 
 +
**[[8gj0]], [[8gj1]], [[8gj2]], [[8gj3]] - EcDpo III + DNA – Cryo EM<br />
 +
 
 +
*DNA polymerase III subunit gamma+delta+delta’+tau+psi or clamp loader
 +
 
 +
**[[8giy]], [[8giz]] - EcDpo III + nucleotide– Cryo EM<br />
*DNA polymerase IV
*DNA polymerase IV
**[[4ir1]], [[4ir9]], [[4irc]], [[4ird]], [[4irk]], [[5zlv]], [[5yye]], [[5yyd]], [[5yv3]], [[5yv2]], [[5yv1]], [[5yv0]], [[5yuz]], [[5yuy]], [[5yux]], [[5yuw]], [[5yuv]], [[5yuu]], [[5yut]], [[5yus]], [[5yur]] - EcPol IV + DNA<br />
**[[4ir1]], [[4ir9]], [[4irc]], [[4ird]], [[4irk]], [[5zlv]], [[5yye]], [[5yyd]], [[5yv3]], [[5yv2]], [[5yv1]], [[5yv0]], [[5yuz]], [[5yuy]], [[5yux]], [[5yuw]], [[5yuv]], [[5yuu]], [[5yut]], [[5yus]], [[5yur]] - EcPol IV + DNA<br />
-
**[[4r8u]], [[5c5j]], [[4q45]], [[4q44]], [[4q43]], [[6ig1]] - EcPol IV + DNA + nucleotide<br />
+
**[[4q45]], [[4q44]], [[4q43]], [[4r8u]], [[5c5j]], [[6ig1]] - EcPol IV + DNA + nucleotide<br />
**[[6jup]], [[6juq]] - EcPol IV (mutant) + DNA + nucleotide<br />
**[[6jup]], [[6juq]] - EcPol IV (mutant) + DNA + nucleotide<br />
**[[2rdi]] - SsPol IV <br />
**[[2rdi]] - SsPol IV <br />
-
**[[1s9f]], [[1s97]], [[1s0m]], [[1s0n]], [[1s0o]], [[1s10]], [[1n48]], [[1n56]], [[1jx4]], [[1jxl]], [[2xca]], [[2xcp]], [[2w8k]], [[2w8l]], [[2rdj]], [[2v9w]], [[2va2]], [[2va3]], [[2ia6]], [[2ibk]], [[2jef]], [[2jeg]], [[2jei]], [[2jej]], [[2imw]], [[2j6s]], [[2j6t]], [[2j6u]], [[2asd]], [[2asj]], [[2asl]], [[2atl]], [[2au0]], [[2c22]], [[2c28]], [[2c2d]], [[2c2e]], [[2c2r]], [[2agp]], [[2agq]], [[2bqr]], [[2bqu]], [[2br0]], [[2bq3]], [[3khg]], [[3khh]], [[3khl]], [[3khr]], [[3t5h]], [[3t5j]], [[3t5k]], [[3t5l]], [[3v6h]], [[3v6j]], [[3v6k]], [[4gc6]], [[4gc7]], [[4juz]], [[4jv0]], [[4jv1]], [[4jv2]], [[4qw8]], [[4qw9]], [[4qwa]], [[4qwb]], [[4qwc]], [[4qwd]], [[4qwe]], [[4ruc]], [[4rua]], [[4tqr]], [[4tqs]], [[5edw]], [[6vg6]], [[6vgm]], [[6vkp]], [[6vnp]], [[7kle]], [[7klf]] - SsPol IV + DNA + nucleotide<br />
+
**[[1s9f]], [[1s97]], [[1s0m]], [[1s0n]], [[1s0o]], [[1s10]], [[1n48]], [[1n56]], [[1jx4]], [[1jxl]], [[2xca]], [[2xcp]], [[2w8k]], [[2w8l]], [[2rdj]], [[2v9w]], [[2va2]], [[2va3]], [[2ia6]], [[2ibk]], [[2jef]], [[2jeg]], [[2jei]], [[2jej]], [[2imw]], [[2j6s]], [[2j6t]], [[2j6u]], [[2asd]], [[2asj]], [[2asl]], [[2atl]], [[2au0]], [[2c22]], [[2c28]], [[2c2d]], [[2c2e]], [[2c2r]], [[2agp]], [[2agq]], [[2bqr]], [[2bqu]], [[2br0]], [[2bq3]], [[3khg]], [[3khh]], [[3khl]], [[3khr]], [[3t5h]], [[3t5j]], [[3t5k]], [[3t5l]], [[3v6h]], [[3v6j]], [[3v6k]], [[4gc6]], [[4gc7]], [[4juz]], [[4jv0]], [[4jv1]], [[4jv2]], [[4qw8]], [[4qw9]], [[4qwa]], [[4qwb]], [[4qwc]], [[4qwd]], [[4qwe]], [[4ruc]], [[4rua]], [[4tqr]], [[4tqs]], [[5edw]], [[6vg6]], [[6vgm]], [[[6vkp]], [6vnp]], [[7kle]], [[7klf]] - SsPol IV + DNA + nucleotide<br />
**[[3pr4]], [[3pr5]], [[2r8g]], [[2r8h]], [[2r8i]], [[2uvr]], [[2uvu]], [[2uvv]], [[2uvw]] - SsPol IV (mutant) + DNA + nucleotide <br />
**[[3pr4]], [[3pr5]], [[2r8g]], [[2r8h]], [[2r8i]], [[2uvr]], [[2uvu]], [[2uvv]], [[2uvw]] - SsPol IV (mutant) + DNA + nucleotide <br />
-
**[[2xc9]], [[3m9m]], [[3m9n]], [[3m9o]], [[2v4q]], [[2v4r]], [[2ago]], [[1ryr]], [[1rys]], [[2w9a]], [[2w9b]], [[2w9c]], [[3gii]], [[3gij]], [[3gik]], [[3gil]], [[3gim]], [[3qz7]], [[3qz8]], [[3pvx]], [[3pw0]], [[3pw2]], [[3pw4]], [[3pw5]], [[3pw7]], [[3raq]], [[3rax]], [[3rb0]], [[3rb3]], [[3rb4]], [[3rb6]], [[3rbd]], [[3rbe]], [[4hyk]], [[4fbt]], [[4fbu]], [[4g3i]], [[4rzr]], [[6l84]], [[6l97]] - SsPol IV + DNA<br />
+
**[[1ryr]], [[1rys]], [[2ago]], [[2v4q]], [[2v4r]], [[2w9a]], [[2w9b]], [[2w9c]], [[2xc9]], [[3gii]], [[3gij]], [[3gik]], [[3gil]], [[3gim]], [[3m9m]], [[3m9n]], [[3m9o]], [[3pvx]], [[3pw0]], [[3pw2]], [[3pw4]], [[3pw5]], [[3pw7]], [[3qz7]], [[3qz8]], [[3raq]], [[3rax]], [[3rb0]], [[3rb3]], [[3rb4]], [[3rb6]], [[3rbd]], [[3rbe]], [[4fbt]], [[4fbu]], [[4g3i]], [[4hyk]], [[4rzr]], [[6l84]], [[6l97]] - SsPol IV + DNA<br />
**[[3fds]] – SsPol IV + PCNA B + PCNA C<br />
**[[3fds]] – SsPol IV + PCNA B + PCNA C<br />
-
**[[3bq2]], [[3bq0]] – SaPol IV + DNA – ''Sulfolobus acidocaldarius''<br />
+
**[[3bq2]], [[3bq0]] – SaPol IV + DNA – Sulfolobus acidocaldarius<br />
**[[3bq1]], [[4f4w]], [[4f4x]], [[4f4y]], [[4f4z]], [[4f50]] - SaPol IV + DNA + nucleotide<br />
**[[3bq1]], [[4f4w]], [[4f4x]], [[4f4y]], [[4f4z]], [[4f50]] - SaPol IV + DNA + nucleotide<br />
**[[4nlg]] - SaPol IV (mutant) + DNA<br />
**[[4nlg]] - SaPol IV (mutant) + DNA<br />
Line 212: Line 233:
**[[5ikn]] - T7Dpo + thioredoxin + DNA primase/helicase<br />
**[[5ikn]] - T7Dpo + thioredoxin + DNA primase/helicase<br />
-
*DNA polymerase
+
*Viral DNA polymerase
**[[2gv9]] – HsvDpo – Herpes simplex virus<br />
**[[2gv9]] – HsvDpo – Herpes simplex virus<br />
**[[7luf]] – HsvDpo + DNA<br />
**[[7luf]] – HsvDpo + DNA<br />
 +
**[[8vq2]] – HsvDpo + DNA + inhibitor<br />
 +
**[[8ojc]], [[8ojd]] – HsvDpo + DNA – Cryo EM<br />
 +
**[[8exx]], [[8oj6]], [[8oj7]], [[8oja]], [[8ojb]], [[8v1q]], [[8v1r]], [[8v1s]] – HsvDpo + Pol processivity factor + DNA – Cryo EM<br />
 +
**[[8v1t]] – HsvDpo + Pol processivity factor + DNA + drug – Cryo EM<br />
**[[5n2g]], [[5n2e]] – VvDpo – Vaccinia virus<br />
**[[5n2g]], [[5n2e]] – VvDpo – Vaccinia virus<br />
**[[5n2h]] – VvDpo (mutant) <br />
**[[5n2h]] – VvDpo (mutant) <br />
 +
**[[8q3r]] – VvDpo + Pol processivity factor + E4R – Cryo EM<br />
**[[5mdn]] – Dpo – ''Pyrobaculum calidifontis''<br />
**[[5mdn]] – Dpo – ''Pyrobaculum calidifontis''<br />
**[[1bgx]] – TaDpo + TP7 antibody<br />
**[[1bgx]] – TaDpo + TP7 antibody<br />
Line 225: Line 251:
**[[3uiq]], [[4dtj]], [[4dtm]], [[4dtn]], [[4dto]], [[4dtp]], [[4dtr]], [[4dts]], [[4dtu]], [[4dtx]], [[4du1]], [[4du3]], [[4du4]] - EpDpo + DNA<br />
**[[3uiq]], [[4dtj]], [[4dtm]], [[4dtn]], [[4dto]], [[4dtp]], [[4dtr]], [[4dts]], [[4dtu]], [[4dtx]], [[4du1]], [[4du3]], [[4du4]] - EpDpo + DNA<br />
**[[3nci]], [[3lds]], [[3l8b]], [[3cq8]], [[3cfp]], [[3cfr]], [[3kd1]], [[3kd5]], [[4e3s]] - EpDpo (mutant) + DNA <br />
**[[3nci]], [[3lds]], [[3l8b]], [[3cq8]], [[3cfp]], [[3cfr]], [[3kd1]], [[3kd5]], [[4e3s]] - EpDpo (mutant) + DNA <br />
-
**[[3ndk]], [[3ne6]], [[3ngi]], [[3nhg]], [[3nae]], [[3lzj]], [[3lzi]], [[2ozs]], [[2p5g]], [[2dy4]], [[1q9x]], [[1q9y]], [[1ig9]], [[3qep]], [[3rma]], [[3rmb]], [[3rmc]], [[3rmd]], [[3rwu]], [[3s9h]], [[3scx]], [[3si6]], [[3sjj]], [[3snn]], [[3spy]], [[3spz]], [[3sq0]], [[3sq1]], [[3sq2]], [[3sq4]], [[3sun]], [[3suo]], [[3sup]], [[3suq]], [[3tab]], [[3tae]], [[3taf]], [[3tag]], [[4i9q]], [[4j2a]], [[4j2b]], [[4j2d]], [[4j2e]], [[4khn]], [[4khq]], [[4khs]], [[4khu]], [[4khw]], [[4khy]], [[4ki4]], [[4ki6]], [[4m3r]], [[4m3t]], [[4m3u]], [[4m3w]], [[4m3x]], [[4m3y]], [[4m3z]], [[4m41]], [[4m42]], [[4m45]], [[7f4y]] - EpDpo (mutant) + DNA + nucleotide<br />
+
**[[1ig9]], [[1q9x]], [[1q9y]], [[2dy4]], [[2ozs]], [[2p5g]], [[3ndk]], [[3ne6]], [[3ngi]], [[3nhg]], [[3nae]], [[3lzj]], [[3lzi]], [[3qep]], [[3rma]], [[3rmb]], [[3rmc]], [[3rmd]], [[3rwu]], [[3s9h]], [[3scx]], [[3si6]], [[3sjj]], [[3snn]], [[3spy]], [[3spz]], [[3sq0]], [[3sq1]], [[3sq2]], [[3sq4]], [[3sun]], [[3suo]], [[3sup]], [[3suq]], [[3tab]], [[3tae]], [[3taf]], [[3tag]], [[4i9q]], [[4j2a]], [[4j2b]], [[4j2d]], [[4j2e]], [[4khn]], [[4khq]], [[4khs]], [[4khu]], [[4khw]], [[4khy]], [[4ki4]], [[4ki6]], [[4m3r]], [[4m3t]], [[4m3u]], [[4m3w]], [[4m3x]], [[4m3y]], [[4m3z]], [[4m41]], [[4m42]], [[4m45]], [[5gnq]] - EpDpo (mutant) + DNA + nucleotide<br />
-
**[[1clq]], [[3iuq]] - EpDpo + DNA + nucleotide<br />
+
**[[1clq]], [[3iuq]], [[7f4y]] - EpDpo + DNA + nucleotide<br />
**[[2oyq]], [[2ozm]], [[2p5o]], [[2dtu]], [[3qei]], [[3qer]], [[3qes]], [[3qet]], [[3qev]], [[3qew]], [[3qex]], [[3qnn]], [[3qno]], [[4fj5]], [[4fj7]], [[4fj8]], [[4fj9]], [[4fjg]], [[4fjh]], [[4fji]], [[4fjj]], [[4fjk]], [[4fjl]], [[4fjm]], [[4fjn]], [[4fjx]], [[4fk0]], [[4fk2]], [[4fk4]] - EpDpo (mutant) + DNA + nucleotide analog<br />
**[[2oyq]], [[2ozm]], [[2p5o]], [[2dtu]], [[3qei]], [[3qer]], [[3qes]], [[3qet]], [[3qev]], [[3qew]], [[3qex]], [[3qnn]], [[3qno]], [[4fj5]], [[4fj7]], [[4fj8]], [[4fj9]], [[4fjg]], [[4fjh]], [[4fji]], [[4fjj]], [[4fjk]], [[4fjl]], [[4fjm]], [[4fjn]], [[4fjx]], [[4fk0]], [[4fk2]], [[4fk4]] - EpDpo (mutant) + DNA + nucleotide analog<br />
**[[2atq]] – EpDpo + GP32<br />
**[[2atq]] – EpDpo + GP32<br />
**[[1noy]] – T4Dpo + DNA <br />
**[[1noy]] – T4Dpo + DNA <br />
**[[1noz]] – T4Dpo residues 1-388<br />
**[[1noz]] – T4Dpo residues 1-388<br />
-
**[[2ex3]] – BpDpo (mutant) + DNA terminal protein – Bacillus phage 29<br />
+
**[[2ex3]] – BpDpo (mutant) + DNA terminal protein – Bacillus phage 29<br />
**[[2py5]], [[2pzs]], [[1xhz]], [[1xi1]] – BpDpo (mutant) + DNA <br />
**[[2py5]], [[2pzs]], [[1xhz]], [[1xi1]] – BpDpo (mutant) + DNA <br />
**[[2pyj]], [[2pyl]] - BpDpo (mutant) + DNA + nucleotide<br />
**[[2pyj]], [[2pyl]] - BpDpo (mutant) + DNA + nucleotide<br />
**[[1xhx]] - BpDpo (mutant) <br />
**[[1xhx]] - BpDpo (mutant) <br />
 +
**[[8k8s]] - mpvDpo (mutant) + DNA + nucleotide – monkeypox virus – Cryo EM<br />
 +
**[[8wpk]], [[8wpp]] - mpvDpo + Pol processivity factor – Cryo EM<br />
 +
**[[8wpe]], [[8wpf]], [[9enp]] - mpvDpo + Pol processivity factor + DNA + nucleotide – Cryo EM<br />
 +
**[[8hpa]], [[8k8u]], [[9k9t]], ]]9k9v]] - mpvDpo + Pol processivity factor + E4R + DNA – Cryo EM<br />
 +
**[[9hlz]], [[8hm0]] - mpvDpo + Pol processivity factor + E4R – Cryo EM<br />
 +
**[[8hdz]], [[8hoy]], [[8j86]], [[9k9s]], [[9k9u]] - mpvDpo (mutant) + Pol processivity factor + E4R – Cryo EM<br />
 +
**[[8hg1]], [[8j8f]], [[9k9r]] - mpvDpo + Pol processivity factor + E4R + DNA + nucleotide – Cryo EM<br />
 +
**[[8j8g]] - mpvDpo + Pol processivity factor + E4R + DNA + drug – Cryo EM<br />
 +
**[[8ywg]] – AsfvDpo – Cryo EM<br />
 +
**[[8ywi]], [[8ywm]] – AsfvDpo + DNA – Cryo EM<br />
 +
**[[7pbk]] – Dpo I – Vibrio phage<br />
 +
**[[7r0k]] – Dpo I – Thermus phage<br />
 +
 +
*Bacterial DNA polymerase
 +
**[[3a2f]] - PfDpo + PCNA - ''Pyrococcus furiosus''<br />
**[[3a2f]] - PfDpo + PCNA - ''Pyrococcus furiosus''<br />
**[[2jgu]], [[4ahc]] – PfDpo<br />
**[[2jgu]], [[4ahc]] – PfDpo<br />
**[[4ail]] – PfDpo + DNA<br />
**[[4ail]] – PfDpo + DNA<br />
-
**[[1tgo]], [[7b06]], [[7b07]], [[7b08]] - TgDpo – ''Thermococcus gorgonarius''<br />
+
**[[1tgo]], [[7b06]], [[7b07]], [[7b08]], [[9gp8]] - TgDpo – ''Thermococcus gorgonarius''<br />
**[[2vwk]] - TgDpo (mutant) <br />
**[[2vwk]] - TgDpo (mutant) <br />
**[[7b0h]] – TgDpo + DNA <br />
**[[7b0h]] – TgDpo + DNA <br />
Line 246: Line 287:
**[[5vu9]], [[5vu8]], [[5vu7]], [[5vu6]], [[5omf]] - TkDpo + DNA<br />
**[[5vu9]], [[5vu8]], [[5vu7]], [[5vu6]], [[5omf]] - TkDpo + DNA<br />
**[[4k8z]] - TkDpo (mutant) + DNA<br />
**[[4k8z]] - TkDpo (mutant) + DNA<br />
 +
**[[9emi]] - TkDpo + DNA + nucleotide derivative<br />
**[[6q4t]] - TkDpo (mutant) + DNA + nucleotide derivative<br />
**[[6q4t]] - TkDpo (mutant) + DNA + nucleotide derivative<br />
-
**[[1qht]] - ThDpo (mutant) – Thermococcus<br />
+
**[[1qht]] - ThDpo (mutant) – ''Thermococcus''<br />
**[[4k8x]], [[5omv]], [[5omq]], [[6is7]], [[6isf]], [[6isg]], [[6ish]], [[6isi]] - ThDpo (mutant) + DNA<br />
**[[4k8x]], [[5omv]], [[5omq]], [[6is7]], [[6isf]], [[6isg]], [[6ish]], [[6isi]] - ThDpo (mutant) + DNA<br />
**[[4yfu]] - Dpo (mutant) + DNA - Bacillus<br />
**[[4yfu]] - Dpo (mutant) + DNA - Bacillus<br />
**[[1d5a]] – DeDpo <br />
**[[1d5a]] – DeDpo <br />
 +
**[[7sxq]] - PfDpo (mutant) – ''Plasmodium falciparum''<br />
 +
**[[9dg1]] – PfDpo + DNA <br />
 +
**[[8s87]] – TkDpo <br />
 +
**[[8s84]] - TkDpo + DNA + nucleotide<br />
 +
**[[7r06]], [[7z0z]] – LlDpo – ''Lactococcus lactis''<br />
 +
**[[8oz7]] – LlDpo + DNA <br />
*DNA polymerase alpha
*DNA polymerase alpha
Line 260: Line 308:
**[[4bpx]] - hDpo α catalytic subunit + DNA primase small subunit <br />
**[[4bpx]] - hDpo α catalytic subunit + DNA primase small subunit <br />
**[[5exr]] - hDpo α catalytic+B subunits + DNA primase small+large subunits <br />
**[[5exr]] - hDpo α catalytic+B subunits + DNA primase small+large subunits <br />
 +
**[[8qj7]], [[8vy3]], [[9c8v]] - hDpo α catalytic+B subunits + DNA primase small+large subunits – Cryo EM<br />
 +
**[[8d9d]] - hDpo α catalytic+B subunits + DNA primase small+large subunits + DNA + nucleotide – Cryo EM<br />
 +
**[[8d96]] - hDpo α catalytic subunit + DNA primase large subunit + DNA – Cryo EM<br />
 +
**[[9mj5]] - hDpo α catalytic subunit + RPA + DNA – Cryo EM<br />
 +
**[[8b9c]], [[8b9d]] - hDpo α in replisome complex – Cryo EM<br />
**[[7opl]] - hDpo α catalytic+B subunits + DNA primase small+large subunits + Nsp1 – Cryo EM<br />
**[[7opl]] - hDpo α catalytic+B subunits + DNA primase small+large subunits + Nsp1 – Cryo EM<br />
-
**[[7u5c]], [[8d08]] - hDpo α catalytic+B subunits + DNA primase small+large subunits + CST + DNA – Cryo EM<br />
+
**[[7u5c]], [[8d08]], [[8d0b]], [[8d0k]] - hDpo α catalytic+B subunits + DNA primase small+large subunits + CST + DNA – Cryo EM<br />
**[[4q5v]] - hDpo α catalytic subunit + DNA + RNA + aphidicolin <br />
**[[4q5v]] - hDpo α catalytic subunit + DNA + RNA + aphidicolin <br />
**[[4qcl]], [[7n2m]] - hDpo α catalytic subunit + DNA + RNA + nucleotide <br />
**[[4qcl]], [[7n2m]] - hDpo α catalytic subunit + DNA + RNA + nucleotide <br />
-
**[[2keb]] - hDpo alphaB - NMR <br />
+
**[[2keb]] - hDpo B - NMR <br />
-
**[[1n5g]], [[1k0p]], [[1k18]] - hDpo alpha zinc finger domain – NMR<br />
+
**[[1n5g]], [[1k0p]], [[1k18]] - hDpo zinc finger domain – NMR<br />
-
**[[7uy7]], [[7uy8]] - Dpo α B subunit + DNA primase small+large subunits – ''Tetrahymena thermophile'' - Cryo EM<br />
+
**[[8g99]], [[8v5n]], [[8v5o]], [[8v6i]] - fDpo α catalytic+B subunits + DNA primase large subunit – frog – Cryo EM <br />
 +
**[[8g9f]], [[8v5m]], [[8v6j]] - fDpo α catalytic+B subunits + DNA primase large subunit + DNA – Cryo EM <br />
 +
**[[8v6g]], [[8v6h]] - fDpo α catalytic+B subunits + DNA primase large subunit + DNA + RNA – Cryo EM <br />
 +
**[[8ucu]], [[8ucv]], [[8ucw]] - fDpo α catalytic subunit 335-1458 + DNA + RNA – Cryo EM <br />
 +
**[[8g9l]], [[8g9o]] - fDpo α catalytic subunit 335-1458 + DNA primase large subunit + DNA + RNA – Cryo EM <br />
 +
**[[8g9n]] - fDpo α catalytic subunit 335-1458 + DNA + RNA + nucleotide – Cryo EM <br />
 +
**[[7uy7]], [[7uy8l]] - Dpo α B subunit + DNA primase small+large subunits – ''Tetrahymena thermophile'' - Cryo EM<br />
*DNA polymerase beta
*DNA polymerase beta
-
**[[4ppx]] - hDpo + spiroiminohydantoin + DNA<br />
+
**[[4ppx]] - hDpo + spiroiminohydantoin + DNA<br />
-
**[[1zjm]], [[1tv9]], [[1tva]], [[1bpx]], [[1bpz]], [[1zqa]], [[1zqb]], [[1zqc]], [[1zqd]], [[1zqf]], [[1zqg]], [[1zqh]], [[1zqi]], [[1zaj]], [[1zqk]], [[1zql]], [[1zqm]], [[1zqn]], [[1zqo]], [[1zqp]], [[1zqq]], [[1zqr]], [[1zqs]], [[1zqt]], [[1zqu]], [[1zqv]], [[1zqw]], [[1zqx]], [[1zqy]], [[1zqz]], [[1zqe]], [[3q8p]], [[3q8q]], [[3lk9]], [[3mby]], [[3isb]], [[3isc]], [[3gdx]], [[3rh4]], [[3rh5]], [[3rh6]], [[4gxi]], [[4gxj]], [[4gxk]], [[4kld]], [[4kle]], [[4klf]], [[4klg]], [[4klh]], [[4kli]], [[4klj]], [[4kll]], [[4klm]], [[4klo]], [[4klq]], [[4kls]], [[4klt]], [[4klu]], [[1zqj]], [[4lvs]], [[4m2y]], [[4m47]], [[4nlk]], [[4nln]], [[4nlz]], [[4nm1]], [[4nm2]], [[4pgy]], [[4tup]], [[4tuq]], [[4tur]], [[4tus]], [[5wo0]], [[5wnz]], [[5wny]], [[5wnx]], [[5vs4]], [[5vs3]], [[5vs2]], [[5vs1]], [[5vs0]], [[5vrz]], [[5vry]], [[5vrx]], [[5vrw]], [[5vez]], [[5v1r]], [[5v1p]], [[5v1o]], [[5v1n]], [[5v1j]], [[5v1i]], [[5v1h]], [[5v1g]], [[5v1f]], [[5ugp]], [[5ugo]], [[5ugn]], [[5u9h]], [[5u8i]], [[5u8h]], [[5u8g]], [[5u2t]], [[5u2s]], [[5u2r]], [[5tzv]], [[5tbc]], [[5tbb]], [[5tba]], [[5tb9]], [[5tb8]], [[5j2k]], [[5j2j]], [[5j2i]], [[5j2h]], [[5j2g]], [[5j2f]], [[5j2e]], [[5j2d]], [[5j2c]], [[5j2b]], [[5j2a]], [[5j29]], [[5j0y]], [[5j0x]], [[5j0w]], [[5j0u]], [[5j0t]], [[5j0s]], [[5j0r]], [[5j0q]], [[5j0p]], [[5j0o]], [[5dbc]], [[5dbb]], [[5dba]], [[5db9]], [[5db8]], [[5db7]], [[5db6]], [[6g2q]], [[6ph5]], [[7ice]], [[7icf]], [[7ici]], [[7icj]], [[7icl]], [[7icm]], [[7icp]], [[7icr]], [[7ict]], [[7icg]], [[7ich]], [[7icj]], [[7ick]], [[7icm]], [[7icn]], [[7ico]], [[7icp]], [[7icq]], [[7icr]], [[7ics]], [[7ict]], [[7icu]], [[7icv]], [[7k97]], [[8icb]], [[8icc]], [[9icj]], [[9ick]], [[9icl]], [[9icm]], [[9icp]], [[9icw]], [[9icx]], [[9icy]] - hDpo beta + DNA<br />
+
**[[1zjm]], [[1tv9]], [[1tva]], [[1bpx]], [[1bpz]], [[1zqa]], [[1zqb]], [[1zqc]], [[1zqd]], [[1zqf]], [[1zqg]], [[1zqh]], [[1zqi]], [[1zaj]], [[1zqk]], [[1zql]], [[1zqm]], [[1zqn]], [[1zqo]], [[1zqp]], [[1zqq]], [[1zqr]], [[1zqs]], [[1zqt]], [[1zqu]], [[1zqv]], [[1zqw]], [[1zqx]], [[1zqy]], [[1zqz]], [[1zqe]], [[3q8p]], [[3q8q]], [[3lk9]], [[3mby]], [[3isb]], [[3isc]], [[3gdx]], [[3rh4]], [[3rh5]], [[3rh6]], [[4gxi]], [[4gxj]], [[4gxk]], [[4kld]], [[4kle]], [[4klf]], [[4klg]], [[4klh]], [[4kli]], [[4klj]], [[4kll]], [[4klm]], [[4klo]], [[4klp]], [[4klq]], [[4kls]], [[4klt]], [[4klu]], [[1zqj]], [[4lvs]], [[4m2y]], [[4m47]], [[4nlk]], [[4nln]], [[4nlz]], [[4nm1]], [[4nm2]], [[4pgy]], [[4tup]], [[4tuq]], [[4tur]], [[4tus]], [[5wo0]], [[5wnz]], [[5wny]], [[5wnx]], [[5vs4]], [[5vs3]], [[5vs2]], [[5vs1]], [[5vs0]], [[5vrz]], [[5vry]], [[5vrx]], [[5vrw]], [[5vez]], [[5v1r]], [[5v1p]], [[5v1o]], [[5v1n]], [[5v1j]], [[5v1i]], [[5v1h]], [[5v1g]], [[5v1f]], [[5ugp]], [[5ugo]], [[5ugn]], [[5u9h]], [[5u8i]], [[5u8h]], [[5u8g]], [[5u2t]], [[5u2s]], [[5u2r]], [[5tzv]], [[5tbc]], [[5tbb]], [[5tba]], [[5tb9]], [[5tb8]], [[5j2k]], [[5j2j]], [[5j2i]], [[5j2h]], [[5j2g]], [[5j2f]], [[5j2e]], [[5j2d]], [[5j2c]], [[5j2b]], [[5j2a]], [[5j29]], [[5j0y]], [[5j0x]], [[5j0w]], [[5j0u]], [[5j0t]], [[5j0s]], [[5j0r]], [[5j0q]], [[5j0p]], [[5j0o]], [[5dbc]], [[5dbb]], [[5dba]], [[5db9]], [[5db8]], [[5db7]], [[5db6]], [[6g2q]], [[6ph5]], [[7ice]], [[7icf]], [[7ici]], [[7icj]], [[7icl]], [[7icm]], [[7icp]], [[7icr]], [[7ict]], [[7icg]], [[7ich]], [[7icj]], [[7ick]], [[7icm]], [[7icn]], [[7ico]], [[7icp]], [[7icq]], [[7icr]], [[7ics]], [[7ict]], [[7icu]], [[7icv]], [[7k97]], [[8icb]], [[8icc]], [[8vf8]], [[8vf9]], [[8vfa]], [[8vfb]], [[8vfc]], [[8vfe]], [[8vff]], [[9vfg]], [[8vfi]], [[8vfj]], [[9icj]], [[9ick]], [[9icl]], [[9icm]], [[9icp]], [[9icw]], [[9icx]], [[9icy]] - hDpo + DNA<br />
-
**[[1bpy]], [[1mq2]], [[1mq3]], [[1zjn]], [[2pxi]], [[2iso]], [[2isp]], [[2i9g]], [[2fmp]], [[2fmq]], [[2fms]], [[3jpn]], [[3jpo]], [[3jpp]], [[3jpq]], [[3jpr]], [[3jpt]], [[3jps]], [[3isd]], [[3c2k]], [[3c2l]], [[3c2m]], [[3rje]], [[3rjf]], [[3rjg]], [[3rjh]], [[3rji]], [[3rjj]], [[3rjk]], [[3tfr]], [[3tfs]], [[4do9]], [[4doa]], [[4dob]], [[4doc]], [[4mf2]], [[4mf8]], [[4mfa]], [[4mfc]], [[4mff]], [[4nxz]], [[4ny8]], [[4o5c]], [[4o5e]], [[4o5k]], [[4o9m]], [[4p2h]], [[4pgq]], [[4pgx]], [[4pha]], [[4phd]], [[4uaw]], [[4uay]], [[4uaz]], [[4ub1]], [[4ub2]], [[4ub3]], [[4ub4]], [[4ub5]], [[4ubb]], [[4ubc]], [[4z6f]], [[4z6e]], [[4z6d]], [[4z6c]], [[4yn4]], [[4ymo]], [[4ymn]], [[4ymm]], [[4rt3]], [[4rt2]], [[4rq8]], [[4rq7]], [[4rq6]], [[4rq5]], [[4rq4]], [[4rq3]], [[4rq2]], [[4rq1]], [[4rq0]], [[4rpz]], [[4rpy]], [[4rpx]], [[4php]], [[4phe]], [[4ph5]], [[5eoz]], [[5bpc]], [[5bom]], [[5bol]], [[7mz0]], [[7mz1]], [[7mz2]], [[7mz3]], [[7mz4]], [[7mzb]], [[7rbe]], [[7rbf]], [[7rbg]], [[7rbh]], [[7rbi]], [[7rbj]], [[7rbk]], [[7rbl]], [[7rbm]], [[7rbn]], [[7rbo]], [[7s9j]], [[7s9k]], [[7s9l]], [[7s9m]], [[7s9n]], [[7s9o]], [[7a9p]], [[7s9q]], [[8ica]], [[8ice]], [[8icf]], [[8icg]], [[8ich]], [[8ici]], [[8icj]], [[8ick]], [[8icl]], [[8icm]], [[8icn]], [[8ico]], [[8icp]], [[8icq]], [[8icr]], [[8ics]], [[8ict]], [[8icu]], [[8icv]], [[8icw]], [[8icx]], [[8icy]], [[8icz]], [[9ica]], [[9icb]], [[9icc]], [[9ice]], [[9icf]], [[9icg]], [[9ich]], [[9ici]], [[9icn]], [[9ico]] [[9icq]], [[9icr]], [[9ics]], [[9ict]], [[9icu]], [[9icv]] - hDpo beta + DNA + nucleotide<br />
+
**[[1bpy]], [[1mq2]], [[1mq3]], [[1zjn]], [[2pxi]], [[2iso]], [[2isp]], [[2i9g]], [[2fmp]], [[2fmq]], [[2fms]], [[3jpn]], [[3jpo]], [[3jpp]], [[3jpq]], [[3jpr]], [[3jpt]], [[3jps]], [[3isd]], [[3c2k]], [[3c2l]], [[3c2m]], [[3rje]], [[3rjf]], [[3rjg]], [[3rjh]], [[3rji]], [[3rjj]], [[3rjk]], [[3tfr]], [[3tfs]], [[4do9]], [[4doa]], [[4dob]], [[4doc]], [[4mf2]], [[4mf8]], [[4mfa]], [[4mfc]], [[4mff]], [[4nxz]], [[4ny8]], [[4o5c]], [[4o5e]], [[4o5k]], [[4o9m]], [[4p2h]], [[4pgq]], [[4pgx]], [[4pha]], [[4phd]], [[4uaw]], [[4uay]], [[4uaz]], [[4ub1]], [[4ub2]], [[4ub3]], [[4ub4]], [[4ub5]], [[4ubb]], [[4ubc]], [[4z6f]], [[4z6e]], [[4z6d]], [[4z6c]], [[4yn4]], [[4ymo]], [[4ymn]], [[4ymm]], [[4rt3]], [[4rt2]], [[4rq8]], [[4rq7]], [[4rq6]], [[4rq5]], [[4rq4]], [[4rq3]], [[4rq2]], [[4rq1]], [[4rq0]], [[4rpz]], [[4rpy]], [[4rpx]], [[4php]], [[4phe]], [[4ph5]], [[5eoz]], [[5bpc]], [[5bom]], [[5bol]], [[7mz0]], [[7mz1]], [[7mz2]], [[7mz3]], [[7mz4]], [[7mzb]], [[7rbe]], [[7rbf]], [[7rbg]], [[7rbh]], [[7rbi]], [[7rbj]], [[7rbk]], [[7rbl]], [[7rbm]], [[7rbn]], [[7rbo]], [[7s9j]], [[7s9k]], [[7s9l]], [[7s9m]], [[7s9n]], [[7s9o]], [[7a9p]], [[7s9q]], [[8ica]], [[8ice]], [[8icf]], [[8icg]], [[8ich]], [[8ici]], [[8icj]], [[8ick]], [[8icl]], [[8icm]], [[8icn]], [[8ico]], [[8icp]], [[8icq]], [[8icr]], [[8ics]], [[8ict]], [[8icu]], [[8icv]], [[8icw]], [[8icx]], [[8icy]], [[8icz]], [[8vfd]], [[8vfh]], [[9ica]], [[9icb]], [[9icc]], [[9ice]], [[9icf]], [[9icg]], [[9ich]], [[9ici]], [[9icn]], [[9ico]] [[9icq]], [[9icr]], [[9ics]], [[9ict]], [[9icu]], [[9icv]] - hDpo + DNA + nucleotide<br />
-
**[[2p66]], [[4f5n]], [[6n2t]], [[6n2s]], [[6n2r]], [[6mr8]], [[6mr7]], [[6e3x]], [[6e3w]], [[6e3v]], [[6e3r]], [[6dia]], [[6cub]], [[6cua]], [[6cu9]], [[6ctx]], [[6ctw]], [[6ctv]], [[6ctu]], [[6ctt]], [[6ctr]], [[6ctq]], [[6ctp]], [[6cto]], [[6ctn]], [[6ctm]], [[6ctl]], [[6ctk]], [[6ctj]], [[6cti]], [[6crh]], [[6crc]], [[6crb]], [[6cr9]], [[6cr8]], [[6cr7]], [[6cr6]], [[6cr5]], [[6cr4]], [[6cr3]], [[6cpq]], [[6cly]], [[6bem]], [[6bel]], [[6ph6]], [[6u2o]], [[6u6b]], [[6uok]], [[6uol]], [[6uom]], [[6w2m]], [[7k96]] - hDpo beta + DNA + nucleotide analog<br />
+
**[[2p66]], [[4f5n]], [[6n2t]], [[6n2s]], [[6n2r]], [[6mr8]], [[6mr7]], [[6e3x]], [[6e3w]], [[6e3v]], [[6e3r]], [[6dia]], [[6cub]], [[6cua]], [[6cu9]], [[6ctx]], [[6ctw]], [[6ctv]], [[6ctu]], [[6ctt]], [[6ctr]],
-
**[[4f5o]], [[4f5p]], [[4f5q]], [[4f5r]], [[6dic]], [[6btf]], [[6bte]], [[6nkr]], [[6nks]], [[6nkt]], [[6nku]], [[6nkv]], [[6nkw]], [[6nkx]], [[6nky]], [[6nkz]], [[6nl0]], [[6pkz]] - hDpo beta (mutant) + DNA + nucleotide analog<br />
+
[[6ctq]], [[6ctp]], [[6cto]], [[6ctn]], [[6ctm]], [[6ctl]], [[6ctk]], [[6ctj]], [[6cti]], [[6crh]], [[6crc]], [[6crb]], [[6cr9]], [[6cr8]], [[6cr7]], [[6cr6]], [[6cr5]], [[6cr4]], [[6cr3]], [[6cpq]], [[6cly]], [[6bem]], [[6bel]], [[6ph6]], [[6u2o]], [[6u6b]], [[6uok]], [[6uol]], [[6uom]], [[6w2m]], [[7k96]] - hDpo + DNA + nucleotide analog<br />
-
**[[3ogu]], [[4jwm]], [[4jwn]], [[4m9g]], [[4m9h]], [[4m9j]], [[4m9l]], [[4m9n]], [[4r63]], [[4r64]], [[4r65]], [[4r66]] - hDpo beta (mutant) + DNA<br />
+
**[[4f5o]], [[4f5p]], [[4f5q]], [[4f5r]], [[6dic]], [[6btf]], [[6bte]], [[6nkr]], [[6nks]], [[6nkt]], [[6nku]], [[6nkv]], [[6nkw]], [[6nkx]], [[6nky]], [[6nkz]], [[6nl0]], [[6pkz]] - hDpo (mutant) + DNA + nucleotide analog<br />
-
**[[5hhi]], [[5hhh]] - hDpo beta + DNA + azanide derivative<br />
+
**[[3ogu]], [[4jwm]], [[4jwn]], [[4m9g]], [[4m9h]], [[4m9j]], [[4m9l]], [[4m9n]], [[4r63]], [[4r64]], [[4r65]], [[4r66]] - hDpo (mutant) + DNA<br />
-
**[[2v6z]] - hDpo beta N-terminal (mutant)]] - NMR<br />
+
**[[5hhi]], [[5hhh]] - hDpo + DNA + azanide derivative<br />
-
**[[3k75]], [[3lqc]] - hDpo beta + DNA repair protein XRCC1<br />
+
**[[2v6z]] - hDpo N-terminal (mutant)]] - NMR<br />
-
**[[1rpl]], [[2bpc]], [[1bpe]], [[1bpb]], [[1bpd]], [[3uxn]] - rDpo beta – rat<br />
+
**[[3k75]], [[3lqc]] - hDpo + DNA repair protein XRCC1<br />
-
**[[2van]], [[1jn3]], [[3uxo]], [[3v7l]]- rDpo beta (mutant) <br />
+
**[[9dwg]], [[9dwh]], [[9dwi]], [[9dwk]], [[9dwm]] - hDpo  in nucleosome complex – Cryo EM<br />
-
**[[1dk2]], [[1dk3]], [[1bno]], [[1bnp]] - rDpo beta N-terminal – NMR<br />
+
**[[1rpl]], [[2bpc]], [[1bpe]], [[1bpb]], [[1bpd]], [[3uxn]] - rDpo – rat<br />
-
**[[1nom]] - rDpo beta C-terminal<br />
+
**[[2van]], [[1jn3]], [[3uxo]], [[3v7l]]- rDpo (mutant) <br />
-
**[[1huo]], [[1huz]], [[3v7j]] - rDpo beta + DNA<br />
+
**[[1dk2]], [[1dk3]], [[1bno]], [[1bnp]] - rDpo N-terminal – NMR<br />
-
**[[3uxp]], [[3v72]], [[3v7k]] - rDpo beta (mutant) + DNA <br />
+
**[[1nom]] - rDpo C-terminal<br />
-
**[[1bpe]] - rDpo beta + nucleotide<br />
+
**[[1huo]], [[1huz]], [[3v7j]] - rDpo + DNA<br />
-
**[[2bpf]], [[2bpg]] - rDpo beta + DNA + nucleotide<br />
+
**[[3uxp]], [[3v72]], [[3v7k]] - rDpo (mutant) + DNA <br />
-
**[[8e10]] - mDpo beta<br />
+
**[[1bpe]] - rDpo + nucleotide<br />
-
**[[8e11]] - mDpo beta (mutant)<br />
+
**[[2bpf]], [[2bpg]] - rDpo + DNA + nucleotide<br />
 +
**[[8e10]] - mDpo <br />
 +
**[[8e11]] - mDpo (mutant)<br />
**[[3au2]] – TtDpo β + GTP – ''Thermus thermophilus''<br />
**[[3au2]] – TtDpo β + GTP – ''Thermus thermophilus''<br />
**[[3b0x]], [[3b0y]] – TtDpo β (mutant) + GTP<br />
**[[3b0x]], [[3b0y]] – TtDpo β (mutant) + GTP<br />
**[[3au6]], [[3auo]] – TtDpo β + GTP + DNA<br />
**[[3au6]], [[3auo]] – TtDpo β + GTP + DNA<br />
-
**[[4p4m]], [[4p4o]], [[4p4p]] - Dpo + DNA + nucleotide – ''Leishmania infantum''<br />
+
**[[4p4m]], [[4p4o]], [[4p4p]] - Dpo + DNA + nucleotide – ''Leishmania infantum''<br />
*DNA polymerase beta-like protein
*DNA polymerase beta-like protein
Line 304: Line 365:
*DNA polymerase gamma
*DNA polymerase gamma
-
**[[3ikm]] - hDpo gamma1+gamma2 <br />
+
**[[3ikm]] - hDpo 1+2 <br />
-
**[[3ikl]], [[2g4c]] - hDpo gamma2<br />
+
**[[8v5d]] - hDpo1 – Cryo EM<br />
-
**[[2jw5]] - hDpo gamma BRCT domain<br />
+
**[[3ikl]], [[2g4c]] - hDpo 2<br />
-
**[[1xsl]] - hDpo gamma catalytic domain<br />
+
**[[2jw5]] - hDpo BRCT domain<br />
-
**[[1nzp]] - hDpo gamma lyase domain - NMR<br />
+
**[[1xsl]] - hDpo catalytic domain<br />
-
**[[3pmn]], [[3pnc]], [[3mda]], [[2gws]], [[2bcq]], [[2bcr]], [[2bcs]], [[2bcu]], [[2bcv]], [[1xsp]], [[1rzt]] - hDpo gamma + DNA<br />
+
**[[1nzp]] - hDpo lyase domain - NMR<br />
-
**[[3mgh]], [[3c5f]], [[3c5g]], [[2pfn]] - hDpo gamma (mutant) + DNA<br />
+
**[[3pmn]], [[3pnc]], [[3mda]], [[2gws]], [[2bcq]], [[2bcr]], [[2bcs]], [[2bcu]], [[2bcv]], [[1xsp]], [[1rzt]] - hDpo + DNA<br />
-
**[[3pml]], [[3mdc]], [[1xsn]] - hDpo gamma + DNA + nucleotide<br />
+
**[[8g5i]], [[8g5j]], [[8g5l]], [[8g5m]], [[8g5n]], [[8g5o]], [[8g5s]], [[8t7e]], [[8udl]], [[8v54]], [[8v5r]] - hDpo  + DNA – Cryo EM<br />
-
**[[5c53]], [[5c52]], [[5c51]] - hDpo gamma1 + DNA + nucleotide + pyrimidine derivative<br />
+
**[[8v55]] - hDpo (mutant) + DNA – Cryo EM<br />
-
**[[4ztz]], [[4ztu]] - hDpo gamma1, gamma2 + DNA + nucleotide <br />
+
**[[3mgh]], [[3c5f]], [[3c5g]], [[2pfn]] - hDpo (mutant) + DNA<br />
-
**[[4k4g]], [[4k4h]], [[4k4i]] - hDpo gamma + DNA + nucleotide analog<br />
+
**[[8g5p]] - hDpo  + DNA + RNA – Cryo EM<br />
-
**[[3mgi]], [[3hw8]], [[3hwt]], [[3hx0]], [[2pfo]], [[2pfp]], [[2pfq]] - hDpo gamma (mutant) + DNA + nucleotide<br />
+
**[[3pml]], [[3mdc]], [[1xsn]], [[8udk]] - hDpo + DNA + nucleotide<br />
 +
**[[5c53]], [[5c52]], [[5c51]] - hDpo  + DNA + nucleotide + pyrimidine derivative<br />
 +
**[[4ztz]], [[4ztu]] - hDpo  + DNA + nucleotide <br />
 +
**[[8d33]], [[8d37]], [[8d3r]], [[8d42]], [[9ggf]] - hDpo  + DNA + nucleotide – Cryo EM<br />
 +
**[[9ggb]], [[9ggc]], [[9ggd]], [[9gge]] - hDpo  (mutant) + DNA + nucleotide – Cryo EM<br />
 +
**[[4k4g]], [[4k4h]], [[4k4i]] - hDpo + DNA + nucleotide analog<br />
 +
**[[3mgi]], [[3hw8]], [[3hwt]], [[3hx0]], [[2pfo]], [[2pfp]], [[2pfq]] - hDpo (mutant) + DNA + nucleotide<br />
 +
**[[8f69]] - mDpo 2 + DNA - mouse<br />
*DNA polymerase delta
*DNA polymerase delta
-
**[[3e0j]] - hDpo delta2+delta3<br />
+
**[[3e0j]] - hDpo 2+3<br />
**[[3upq]], [[3uq0]], [[3uq2]] - hDpo δ (mutant) + DNA<br />
**[[3upq]], [[3uq0]], [[3uq2]] - hDpo δ (mutant) + DNA<br />
**[[4fo6]] - hDpo δ (mutant) + DNA + nucleotide analog<br />
**[[4fo6]] - hDpo δ (mutant) + DNA + nucleotide analog<br />
-
**[[6s1m]], [[6s1n]], [[6s1o]], [[6tny]] - hDpo δ subunits catalytic+2+3+4 + PCNA + DNA + nucleotide analog – Cryo EM<br />
+
**[[9ekb]] - hDpo δ subunits catalytic+2+3+4 – Cryo EM<br />
 +
**[[6s1m]], [[6s1n]], [[6s1o]], [[6tny]] - hDpo δ subunits
 +
catalytic+2+3+4 + PCNA + DNA + nucleotide analog – Cryo EM<br />
 +
 
**[[6tnz]] - hDpo δ subunits catalytic+2+3+4 + PCNA + FLAP endonuclease +DNA + nucleotide analog – Cryo EM<br />
**[[6tnz]] - hDpo δ subunits catalytic+2+3+4 + PCNA + FLAP endonuclease +DNA + nucleotide analog – Cryo EM<br />
**[[7kc0]] - hDpo δ + PCNA + POL31 + POL32 +DNA + nucleotide analog – Cryo EM<br />
**[[7kc0]] - hDpo δ + PCNA + POL31 + POL32 +DNA + nucleotide analog – Cryo EM<br />
Line 328: Line 399:
*DNA polymerase epsilon
*DNA polymerase epsilon
-
**[[5vbn]] - hDpo epsilon subunits A+2 <br />
+
**[[5vbn]] - hDpo subunits A+2 <br />
 +
**[[9f6i]], [[9f6j]], [[9f6l]] - hDpo subunit A + DNA – Cryo EM <br />
 +
**[[9b8s]], [[9f6e]], [[9f6f]] - hDpo subunit A + DNA + PCNA – Cryo EM <br />
 +
**[[9b8t]] - hDpo subunit A + DNA + PCNA + nucleotide – Cryo EM <br />
*DNA polymerase zeta
*DNA polymerase zeta
-
**[[3abd]], [[3abe]] - hDpo zeta catalytic subunit Rev3 + mitotic spindle assembly checkpoint protein Rev7<br />
+
**[[3abd]], [[3abe]] - hDpo catalytic subunit Rev3 + mitotic spindle assembly checkpoint protein Rev7<br />
-
**[[6ekm]], [[6bi7]], [[6bcd]], [[6bc8]] - hDpo zeta catalytic subunit + MAD2B<br />
+
**[[6ekm]], [[6bi7]], [[6bcd]], [[6bc8]] - hDpo  catalytic subunit + MAD2B<br />
-
**[[3vu7]], [[4gk0]], [[6ws0]] - hDpo zeta catalytic subunit + DNA repair protein Rev1 + MAD2B<br />
+
**[[3vu7]], [[4gk0]], [[6ws0]] - hDpo  catalytic subunit + DNA repair protein Rev1 + MAD2B<br />
-
**[[6ws5]] - hDpo zeta catalytic subunit + DNA repair protein Rev1 + MAD2B + inhibitor<br />
+
**[[6ws5]] - hDpo  catalytic subunit + DNA repair protein Rev1 + MAD2B + inhibitor<br />
-
**[[4fjo]], [[4gk5]] - hDpo kappa + hDpo zeta catalytic subunit + DNA repair protein Rev1 + MAD2B<br />
+
**[[4fjo]], [[4gk5]] - hDpo + hDpo  catalytic subunit + DNA repair protein Rev1 + MAD2B<br />
-
**[[6v8p]] - hDpo zeta catalytic subunit + hDpo d subunits 3+small – Cryo EM<br />
+
**[[6v8p]] - hDpo  catalytic subunit + hDpo d subunits 3+small – Cryo EM<br />
-
**[[6v93]] - hDpo zeta catalytic+processivity subunits + hDpo d subunits 3+small + DNA + dCTP – Cryo EM<br />
+
**[[6v93]] - hDpo  catalytic+processivity subunits + hDpo delta subunits 3+small + DNA + dCTP – Cryo EM<br />
-
*DNA polymerase eta
+
*DNA polymerase eta or DNA polymerase theta; domains: helicase 1-894; polymerase 1819-2590
-
**[[2i5o]] - hDpo eta ubiquitin-binding zinc finger – NMR<br />
+
**[[2i5o]] - hDpo ubiquitin-binding zinc finger – NMR<br />
-
**[[3wup]] - hDpo eta ubiquitin-binding zinc finger <br />
+
**[[3wup]] - hDpo ubiquitin-binding zinc finger <br />
-
**[[3tq1]], [[4j9k]], [[4j9l]], [[4j9m]], [[4j9n]], [[4j9o]], [[4j9p]], [[4j9q]], [[4j9r]], [[4j9s]], [[6mp3]] - hDpo eta + DNA <br />
+
**[[5a9j]] – hDpo helicase domain <br />
-
**[[3jaa]], [[4dl2]], [[4dl3]], [[4dl4]], [[4dl5]], [[4dl6]], [[4dl7]], [[4eey]], [[4ecq]], [[4ecr]], [[4ecs]], [[4ect]], [[4ecu]], [[4ecv]], [[4ecw]], [[4ecx]], [[4ecy]], [[4ecz]], [[4ed0]], [[4ed1]], [[4ed2]], [[4ed3]], [[4ed6]], [[4ed7]], [[4ed8]], [[4o3n]], [[4o3o]], [[4o3p]], [[4o3q]], [[4o3r]], [[4o3s]], [[4q8e]], [[4q8f]], [[4rnm]], [[4rnn]], [[4rno]], [[3si8]], [[3mr2]], [[3mr3]], [[3mr5]], [[3mr6]], [[5l9x]], [[5l1l]], [[5l1k]], [[5l1j]], [[5l1i]], [[5kg7]], [[5kg6]], [[5kg5]], [[5kg4]], [[5kg3]], [[5kg2]], [[5kg1]], [[5kg0]], [[5kfz]], [[5kfy]], [[5kfx]], [[5kfw]], [[5kfv]], [[5kfu]], [[5kft]], [[5kfs]], [[5kfr]], [[5kfq]], [[5kfp]], [[5kfo]], [[5kfn]], [[5kfm]], [[5kfl]], [[5kfk]], [[5kfj]], [[5kfi]], [[5kfh]], [[5kfg]], [[5kff]], [[5kfe]], [[5kfd]], [[5kfc]], [[5kfb]], [[5kfa]], [[5jum]], [[5f9n]], [[5f9l]], [[5ewg]], [[5ewf]], [[5ewe]], [[5dqi]], [[5dqh]], [[5dqg]], [[5dlg]], [[5dlf]], [[5dgb]], [[5dga]], [[5dg9]], [[5dg8]], [[5dg7]], [[4yr3]], [[4yr2]], [[4yr0]], [[4yqw]], [[4yp3]], [[4ru9]], [[6mxo]], [[6m7v]], [[6m7u]], [[6m7t]], [[6m7p]], [[6m7o]], [[6d0z]], [[6d0m]], [[6mq8]], [[6pl7]], [[6pl8]], [[6plc]], [[6ui2]], [[6uqi]], [[6v5k]], [[6w5x]], [[6wk6]], [[7l69]], [[7lcd]], [[7m7l]], [[7m7m]], [[7m7n]], [[7m7o]], [[7m7p]], [[7m7q]], [[7m7r]], [[7m7s]], [[7m7t]], [[7m7u]], [[7m7y]], [[7m7z]], [[7m80]], [[7m81]], [[7m82]], [[7m83]], [[7m84]], [[7m85]], [[7m86]], [[7m87]], [[7m88]], [[7m89]], [[7m8a]], [[7m8b]], [[7m8c]], [[7m8d]], [[7u72]], [[7u73]], [[7u74]], [[7u75]], [[7u76]], [[7u77]], [[7u78]], [[7u79]], [[7u7a]], [[7u7b]], [[7u7c]], [[7u7d]], [[7u7e]], [[7u7g]], [[7u7f]], [[7u7i]], [[7u7j]], [[7u7k]], [[7u7l]], [[7u7r]], [[7u7s]], [[7u7t]], [[7u7u]], [[7u7v]], [[7u7w]], [[7u7x]], [[7u7y]], [[7u7z]], [[7u80]], [[7u81]], [[7u82]], [[7u83]], [[7u84]], [[8e85]], [[8e86]], [[8e87]], [[8e88]], [[8e89]], [[8e8a]], [[8e8c]], [[8e8d]], [[8e8e]], [[8e8f]], [[8e8g]], [[8e8h]], [[8e8j]], [[8e8k]] - hDpo eta + DNA + nucleotide<br />
+
**[[9asj]], [[9ask]], [[9asl]], [[9bh6]], [[9bh7]] - hDpo  - Cryo EM <br />
-
**[[6pz3]], [[6q02]] - hDpo eta (mutant) + DNA + nucleotide<br />
+
**[[9bp9]], [[9bpa]] - hDpo  + inhibitor - Cryo EM <br />
-
**[[5aga]] - hDpo eta + nucleotide<br />
+
**[[8ski]], [[8w0a]], [[9bh8]], [[9bh9]], [[9bha]], [[9c5q]] - hDpo  helicase domain + DNA - Cryo EM <br />
 +
**[[3tq1]], [[4j9k]], [[4j9l]], [[4j9m]], [[4j9n]], [[4j9o]], [[4j9p]], [[4j9q]], [[4j9r]], [[4j9s]], [[6mp3]], [[8eve]], [[8evf]] - hDpo + DNA <br />
 +
**[[3jaa]], [[3mr2]], [[3mr3]], [[3mr5]], [[3mr6]], [[3si8]], [[4dl2]], [[4dl3]], [[4dl4]], [[4dl5]], [[4dl6]], [[4dl7]], [[4eey]], [[4ecq]], [[4ecr]], [[4ecs]], [[4ect]], [[4ecu]], [[4ecv]], [[4ecw]], [[4ecx]], [[4ecy]], [[4ecz]], [[4ed0]], [[4ed1]], [[4ed2]], [[4ed3]], [[4ed6]], [[4ed7]], [[4ed8]], [[4o3n]], [[4o3o]], [[4o3p]], [[4o3q]], [[4o3r]], [[4o3s]], [[4q8e]], [[4q8f]], [[4rnm]], [[4rnn]], [[4rno]], [[4x0p]], [[4x0q]], [[5l9x]], [[5l1l]], [[5l1k]], [[5l1j]], [[5l1i]], [[5kg7]], [[5kg6]], [[5kg5]], [[5kg4]], [[5kg3]], [[5kg2]], [[5kg1]], [[5kg0]], [[5kfz]], [[5kfy]], [[5kfx]], [[5kfw]], [[5kfv]], [[5kfu]], [[5kft]], [[5kfs]], [[5kfr]], [[5kfq]], [[5kfp]], [[5kfo]], [[5kfn]], [[5kfm]], [[5kfl]], [[5kfk]], [[5kfj]], [[5kfi]], [[5kfh]], [[5kfg]], [[5kff]], [[5kfe]], [[5kfd]], [[5kfc]], [[5kfb]], [[5kfa]], [[5jum]], [[5f9n]], [[5f9l]], [[5ewg]], [[5ewf]], [[5ewe]], [[5dqi]], [[5dqh]], [[5dqg]], [[5dlg]], [[5dlf]], [[5dgb]], [[5dga]], [[5dg9]], [[5dg8]], [[5dg7]], [[4yr3]], [[4yr2]], [[4yr0]], [[4yqw]], [[4yp3]], [[4ru9]], [[6mxo]], [[6m7v]], [[6m7u]], [[6m7t]], [[6m7p]], [[6m7o]], [[6d0z]], [[6d0m]], [[6mq8]], [[6pl7]], [[6pl8]], [[6plc]], [[6ui2]], [[6uqi]], [[6v5k]], [[6w5x]], [[6wk6]], [[7l69]], [[7lcd]], [[7m7l]], [[7m7m]], [[7m7n]], [[7m7o]], [[7m7p]], [[7m7q]], [[7m7r]], [[7m7s]], [[7m7t]], [[7m7u]], [[7m7y]], [[7m7z]], [[7m80]], [[7m81]], [[7m82]], [[7m83]], [[7m84]], [[7m85]], [[7m86]], [[7m87]], [[7m88]], [[7m89]], [[7m8a]], [[7m8b]], [[7m8c]], [[7m8d]], [[7u72]], [[7u73]], [[7u74]], [[7u75]], [[7u76]], [[7u77]], [[7u78]], [[7u79]], [[7u7a]], [[7u7b]], [[7u7c]], [[7u7d]], [[7u7e]], [[7u7g]], [[7u7f]], [[7u7i]], [[7u7j]], [[7u7k]], [[7u7l]], [[7u7r]], [[7u7s]], [[7u7t]], [[7u7u]], [[7u7v]], [[7u7w]], [[7u7x]], [[7u7y]], [[7u7z]], [[7u80]], [[7u81]], [[7u82]], [[7u83]], [[7u84]], [[8e85]], [[8e86]], [[8e87]], [[8e88]], [[8e89]], [[8e8a]], [[8e8c]], [[8e8d]], [[8e8e]], [[8e8f]], [[8e8g]], [[8e8h]], [[8e8j]], [[8e8k]], [[8fn3]], [[8fog]], [[8foh]], [[8foj]], [[8g8h]], [[8g8j]], [[8gbf]], [[8gkr]], [[8gml]], [[8ujt]], [[8ujv]], [[8ujx]], [[8uk4]], [[8v7a]], [[8v7b]], [[8v7c]], [[8v7d]], [[8v7e]], [[8v7f]], [[8v7g]], [[8v7h]], [[8v7j]], [[8v7k]], [[8v7i]], [[9chw]], [[9ci9]], [[9cih]], [[9ciq]] - hDpo + DNA + nucleotide<br />
 +
**[[9au5]], [[9au8]], [[9au9]] - hDpo  + DNA + nucleotide – Cryo EM<br />
 +
**[[6pz3]], [[6q02]] - hDpo (mutant) + DNA + nucleotide<br />
 +
**[[6xbu]], [[7zus]] – hDpo polymerase domain + nucleotide + DNA<br />
 +
**[[5a9f]], [[5aga]] - hDpo + nucleotide<br />
 +
**[[7zx0]], [[7zx1]], [[8e23]], [[8e24]] , [[8gd7]]– hDpo polymerase domain + inhibitor + DNA<br />
 +
**[[8ef9]], [[8efc]], [[8efk]] – Dpo polymerase domain + nucleotide + DNA – Lates calcarifer<br />
*DNA polymerase iota
*DNA polymerase iota
-
**[[3q8r]], [[3q8s]], [[3h4b]], [[3h4d]], [[3gv5]], [[3gv7]], [[3gv8]], [[3epg]], [[3epi]], [[2fll]], [[2fln]], [[2flp]], [[2dpi]], [[2dpj]], [[2alz]], [[1zet]], [[1t3n]], [[4ebc]], [[4ebd]], [[4ebe]], [[4fs1]], [[4fs2]], [[4eyh]], [[4eyi]], [[3g6v]], [[3g6x]], [[3g6y]], [[5ulx]], [[5ulw]], [[5kt7]], [[5kt6]], [[5kt5]], [[5kt4]], [[5kt3]], [[5kt2]] - hDpo iota + DNA + nucleotide<br />
+
**[[3q8r]], [[3q8s]], [[3h4b]], [[3h4d]], [[3gv5]], [[3gv7]], [[3gv8]], [[3epg]], [[3epi]], [[2fll]], [[2fln]], [[2flp]], [[2dpi]], [[2dpj]], [[2alz]], [[1zet]], [[1t3n]], [[4ebc]], [[4ebd]], [[4ebe]], [[4fs1]], [[4fs2]], [[4eyh]], [[4eyi]], [[3g6v]], [[3g6x]], [[3g6y]], [[5ulx]], [[5ulw]], [[5kt7]], [[5kt6]], [[5kt5]], [[5kt4]], [[5kt3]], [[5kt2]] - hDpo + DNA + nucleotide<br />
-
**[[3ngd]], [[3osn]], [[3h40]] - hDpo iota catalytic fragment + DNA <br />
+
**[[3ngd]], [[3osn]], [[3h40]] - hDpo catalytic fragment + DNA <br />
-
**[[2ktf]] - hDpo iota + ubiquitin<br />
+
**[[2ktf]] - hDpo + ubiquitin<br />
-
**[[2l0f]], [[2l0g]] - hDpo iota + ubiquitin – NMR<br />
+
**[[2l0f]], [[2l0g]] - hDpo + ubiquitin – NMR<br />
-
**[[2khu]] - hDpo iota ubiquitin binding motif – NMR<br />
+
**[[2khu]] - hDpo ubiquitin binding motif – NMR<br />
-
**[[2khw]] - hDpoiota ubiquitin binding motif + ubiquitin – NMR<br />
+
**[[2khw]] - hDpo ubiquitin binding motif + ubiquitin – NMR<br />
-
**[[2kwu]], [[2kwv]] - mDpo iota C-terminal + ubiquitin - NMR<br />
+
**[[2kwu]], [[2kwv]] - mDpo C-terminal + ubiquitin - NMR<br />
-
**[[3ai4]] - mDpo iota/yEGFP<br />
+
**[[3ai4]] - mDpo /yEGFP<br />
*DNA polymerase kappa
*DNA polymerase kappa
-
**[[1t94]] - hDpo kappa<br />
+
**[[1t94]] - hDpo <br />
-
**[[3in5]], [[5w2c]], [[5w2a]], [[5t14]] - hDpo kappa + DNA<br />
+
**[[3in5]], [[5w2c]], [[5w2a]], [[5t14]] - hDpo + DNA<br />
-
**[[2w7o]], [[2w7p]], [[2oh2]], [[3pzp]], [[4u6p]], [[6cst]], [[6bs1]], [[6brx]], [[5w2a]], [[5w2c]] - hDpo kappa + DNA + nucleotide<br />
+
**[[2w7o]], [[2w7p]], [[2oh2]], [[3pzp]], [[4u6p]], [[6cst]], [[6bs1]], [[6brx]], [[5w2a]], [[5w2c]] - hDpo + DNA + nucleotide<br />
-
**[[7nv0]], [[7nv1]] - hDpo kappa + PCNA + DNA + nucleotide<br />
+
**[[7nv0]], [[7nv1]] - hDpo + PCNA + DNA + nucleotide<br />
-
**[[4u7c]], [[4y6p]] - hDpo kappa + DNA + benzopyrene derivative<br />
+
**[[4u7c]], [[4y6p]] - hDpo + DNA + benzopyrene derivative<br />
-
**[[2lsi]] - hDpo kappa peptide + hRev1<br />
+
**[[2lsi]] - hDpo peptide + hRev1<br />
-
**[[2lsk]] - mDpo kappa + DNA repair protein Rev1<br />
+
**[[2lsk]] - mDpo + DNA repair protein Rev1<br />
*DNA polymerase lambda
*DNA polymerase lambda
Line 374: Line 456:
**[[5cb1]] – hDpo <br />
**[[5cb1]] – hDpo <br />
**[[5iio]], [[5iin]], [[5iim]], [[5iil]], [[5iik]], [[5iij]], [[5iii]], [[5ddm]] – hDpo + DNA<br />
**[[5iio]], [[5iin]], [[5iim]], [[5iil]], [[5iik]], [[5iij]], [[5iii]], [[5ddm]] – hDpo + DNA<br />
-
**[[5cp2]] – hDpo (mutant) + DNA<br />
+
**[[5cp2]], [[8u0o]] – hDpo (mutant) + DNA<br />
**[[5dkw]], [[5ca7]], [[4xus]], [[4xrh]], [[4xq8]], [[4xa5]], [[4x5v]], [[7m07]], [[7m08]], [[7m09]], [[7m0a]], [[7m0b]], [[7m0c]], [[7m0d]], [[7m0e]] – hDpo + DNA + nucleotide<br />
**[[5dkw]], [[5ca7]], [[4xus]], [[4xrh]], [[4xq8]], [[4xa5]], [[4x5v]], [[7m07]], [[7m08]], [[7m09]], [[7m0a]], [[7m0b]], [[7m0c]], [[7m0d]], [[7m0e]] – hDpo + DNA + nucleotide<br />
-
**[[5cwr]], [[5cr0]], [[5cj7]], [[5chg]], [[7m43]], [[7m44]], [[7m45]], [[7m46]], [[7m47]], [[7m48]], [[7m49]], [[7m4a]], [[7m4b]], [[7m4c]], [[7m4d]], [[7m4e]], [[7m4f]], [[7m4h]], [[7m4i]], [[7m4j]], [[7m4k]], [[7m4l]] – hDpo (mutant) + DNA + nucleotide<br />
+
**[[5cwr]], [[5cr0]], [[5cj7]], [[5chg]], [[7m43]], [[7m44]], [[7m45]], [[7m46]], [[7m47]], [[7m48]], [[7m49]], [[7m4a]], [[7m4b]], [[7m4c]], [[7m4d]], [[7m4e]], [[7m4f]], [[7m4h]], [[7m4i]], [[7m4j]], [[7m4k]], [[7m4l]], [[8u0p]] – hDpo (mutant) + DNA + nucleotide<br />
**[[5ddy]] – hDpo + nucleotide<br />
**[[5ddy]] – hDpo + nucleotide<br />
*DNA polymerase mu or DNA-directed DNA/RNA polymerase
*DNA polymerase mu or DNA-directed DNA/RNA polymerase
-
**[[2htf]], [[2dun]] - hDpo mu BRCT domain residues 24-143 – NMR<br />
+
**[[2htf]], [[2dun]] - hDpo BRCT domain residues 24-143 – NMR<br />
-
**[[4lzd]] - hDpo mu residues 132-494 <br />
+
**[[4lzd]] - hDpo residues 132-494 <br />
-
**[[4lzg]], [[5tyz]], [[5tyy]], [[5tyx]], [[5tyw]], [[5tyv]], [[5tyu]], [[5tyg]], [[5tyf]], [[5tye]], [[5tyd]], [[5tyc]], [[5tyb]], [[5txz]], [[5txx]], [[5tws]], [[5twr]], [[5twq]], [[5twp]], [[5zlc]] - hDpo mu residues 132-494 + DNA <br />
+
**[[4lzg]], [[5tyz]], [[5tyy]], [[5tyx]], [[5tyw]], [[5tyv]], [[5tyu]], [[5tyg]], [[5tyf]], [[5tye]], [[5tyd]], [[5tyc]], [[5tyb]], [[5txz]], [[5txx]], [[5tws]], [[5twr]], [[5twq]], [[5twp]], [[5zlc]] - hDpo residues 132-494 + DNA <br />
-
**[[4yd2]], [[4ycx]] - hDpo mu residues 132-494 (mutant) + DNA <br />
+
**[[4yd2]], [[4ycx]] - hDpo residues 132-494 (mutant) + DNA <br />
-
**[[6ak5]] - hDpo mu residues 132-397+411-494 + nucleotide derivative<br />
+
**[[6ak5]] - hDpo residues 132-397+411-494 + nucleotide derivative<br />
-
**[[6ipn]], [[6ipm]], [[6ipl]], [[6ipk]], [[6ipj]], [[6ipi]], [[6iph]], [[6aec]], [[6aeh]], [[6ak6]] - hDpo mu residues 132-397+411-494 (mutant) + nucleotide derivative<br />
+
**[[6ipn]], [[6ipm]], [[6ipl]], [[6ipk]], [[6ipj]], [[6ipi]], [[6iph]], [[6aec]], [[6aeh]], [[6ak6]] - hDpo residues 132-397+411-494 (mutant) + nucleotide derivative<br />
-
**[[6vez]], [[6vf0]], [[6vf1]], [[6vf2]], [[6vf3]], [[6vf4]], [[6vf5]], [[6vf6]], [[6vf7]], [[6vf8]], [[6vf9]], [[6vfa]], [[6vfb]], [[6vfc]], [[7co6]], [[7co8]], [[7co9]], [[7coa]], [[7cob]], [[7cod]], [[7kss]], [[7kst]], [[7ksu]], [[7ksv]], [[7ksw]], [[7ksx]], [[7ksy]], [[7ksz]], [[7kt0]], [[7kt1]], [[7kt2]], [[7kt3]], [[7kt4]], [[7kt5]], [[7kt6]], [[7kt7]], [[7kt9]], [[7kta]], [[7ktb]], [[7ktc]], [[7ktd]], [[7kte]], [[7ktf]], [[7ktg]], [[7kth]], [[7kti]], [[7ktj]], [[7ktk]], [[7ktl]], [[7ktm]], [[7ktn]] - hDpo mu + DNA + nucleotide derivative<br />
+
**[[6vez]], [[6vf0]], [[6vf1]], [[6vf2]], [[6vf3]], [[6vf4]], [[6vf5]], [[6vf6]], [[6vf7]], [[6vf8]], [[6vf9]], [[6vfa]], [[6vfb]], [[6vfc]], [[7co6]], [[7co8]], [[7co9]], [[7coa]], [[7cob]], [[7cod]], [[7kss]], [[7kst]], [[7ksu]], [[7ksv]], [[7ksw]], [[7ksx]], [[7ksy]], [[7ksz]], [[7kt0]], [[7kt1]], [[7kt2]], [[7kt3]], [[7kt4]], [[7kt5]], [[7kt6]], [[7kt7]], [[7kt9]], [[7kta]], [[7ktb]], [[7ktc]], [[7ktd]], [[7kte]], [[7ktf]], [[7ktg]], [[7kth]], [[7kti]], [[7ktj]], [[7ktk]], [[7ktl]], [[7ktm]], [[7ktn]] - hDpo + DNA + nucleotide derivative<br />
-
**[[4m04]], [[4m0a]], [[4yd1]], [[6ipg]], [[6ipf]], [[6ipe]], [[6ipd]], [[5vz7]], [[5vz8]], [[5vz9]], [[5vza]], [[5vzb]], [[5vzc]], [[5vzd]], [[5vze]], [[5vzf]], [[5vzg]], [[5vzh]], [[5vzi]], [[6ak8]], [[6ak9]], [[6akh]], [[6p1m]], [[6p1n]], [[6p1o]], [[6p1p]], [[6p1q]], [[6p1r]], [[6p1s]], [[6p1t]], [[6p1u]], [[6p1v]], [[6p1w]], [[7coc]] - hDpo mu residues 132-494+411-494 (mutant) + DNA + nucleotide derivative<br />
+
**[[4m04]], [[4m0a]], [[4yd1]], [[6ipg]], [[6ipf]], [[6ipe]], [[6ipd]], [[5vz7]], [[5vz8]], [[5vz9]], [[5vza]], [[5vzb]], [[5vzc]], [[5vzd]], [[5vze]], [[5vzf]], [[5vzg]], [[5vzh]], [[5vzi]], [[6ak8]], [[6ak9]], [[6akh]], [[6p1m]], [[6p1n]], [[6p1o]], [[6p1p]], [[6p1q]], [[6p1r]], [[6p1s]], [[6p1t]], [[6p1u]], [[6p1v]], [[6p1w]], [[7coc]] - hDpo residues 132-494+411-494 (mutant) + DNA + nucleotide derivative<br />
-
**[[2ihm]] - mDpo mu catalytic domain + DNA – mouse<br />
+
**[[2ihm]] - mDpo catalytic domain + DNA <br />
*DNA polymerase nu
*DNA polymerase nu
Line 400: Line 482:
**[[2m2u]], [[2m2v]] – AsfvDpo X + nucleotide – NMR<br />
**[[2m2u]], [[2m2v]] – AsfvDpo X + nucleotide – NMR<br />
**[[2m2w]] – AsfvDpo X + nucleotide + DNA – NMR<br />
**[[2m2w]] – AsfvDpo X + nucleotide + DNA – NMR<br />
-
**[[5xma]], [[5xm9]], [[5xm8]] – AsfvDpo X + DNA<br />
+
**[[5xma]], [[5xm9]], [[5xm8]], [[8e9a]] – AsfvDpo X + DNA<br />
-
**[[2w9m]] – DrDpo X
+
**[[8ild]], [[8ile]], [[8ilf]], [[8ilg]], [[8ilh]], [[8ili]] – AsfvDpo X + DNA + nucleotide – Cryo EM<br />
-
 
+
**[[2w9m]] – DrDpo X
-
*DNA polymerase theta
+
-
 
+
-
**[[5a9j]] – hDpo helicase domain 1-894<br />
+
-
**[[5a9f]], [[5aga]] – hDpo helicase domain + nucleotide<br />
+
-
**[[4x0p]], [[4x0q]] – hDpo helicase domain + nucleotide + DNA<br />
+
-
**[[6xbu]], [[7zus]] – hDpo polymerase domain 1819-2590 + nucleotide + DNA<br />
+
-
**[[7zx0]], [[7zx1]], [[8e23]], [[8e24]] – hDpo polymerase domain + inhibitor + DNA<br />
+
-
**[[8ef9]], [[8efc]], [[8efk]] – Dpo polymerase domain + nucleotide + DNA – Lates calcarifer<br />
+
*DNA polymerase from yeast
*DNA polymerase from yeast
-
**[[3oiq]] - yDpo alpha + cell division control protein 13 <br />
+
**[[3oiq]] - yDpo + cell division control protein 13 <br />
-
**[[3flo]], [[3lgb]] - yDpo alpha subunits A,B<br />
+
**[[3flo]], [[3lgb]] - yDpo  subunits A,B<br />
-
**[[4b08]], [[4fvm]] - yDpo alpha subunit A<br />
+
**[[8foc]], [[8fod]], [[8foe]] - yDpo  subunits A,B + primase small+large subunits – Cryo EM<br />
-
**[[4fxd]], [[4fyd]] - yDpo alpha subunit A + RNA + DNA<br />
+
**[[8fok]] - yDpo  subunits A,B + primase small+large subunits + DNA – Cryo EM<br />
-
**[[5oki]] - yDpo alpha subunit A + DCC1 + chromosome fidelity protein<br />
+
**[[4b08]], [[4fvm]] - yDpo  subunit A<br />
-
**[[3iay]] - yDpo delta catalytic subunit + DNA<br />
+
**[[4fxd]], [[4fyd]] - yDpo  subunit A + RNA + DNA<br />
-
**[[6p1h]] - yDpo delta catalytic+small+3 subunits + DNA + nucleotide – Cryo EM<br />
+
**[[5oki]] - yDpo  subunit A + DCC1 + chromosome fidelity protein<br />
-
**[[6wjv]] - yDpo II epsilon – Cryo EM<br />
+
**[[9c51]], [[9c52]], [[9c53]] – yDpo gamma catalytic+small+3 subunits + DNA + nucleotide – Cryo EM<br />
-
**[[6hv8]] - yDpo II epsilon subunit A+B – Cryo EM<br />
+
**[[9d2i]] – yDpo gamma catalytic subunit + DNA + nucleotide – Cryo EM<br />
-
**[[3oha]], [[3ohb]], [[3mfh]] - yDpo epsilon (mutant) + DNA<br />
+
**[[3iay]] - yDpo catalytic subunit + DNA<br />
-
**[[6i8a]], [[6qib]], [[7r3x]], [[7r3y]] - yDpo II epsilon subunit A + DNA + nucleotide <br />
+
**[[6p1h]] - yDpo catalytic+small+3 subunits + DNA + nucleotide – Cryo EM<br />
-
**[[6g0a]], [[6fwk]], [[3mfi]], [[4m8o]] - yDpo II epsilon subunit A (mutant) + DNA + nucleotide derivative<br />
+
**[[6wjv]] - yDpo II  – Cryo EM<br />
-
**[[6s1c]], [[6s2e]], [[6s2f]] - yDpo II epsilon subunit A (mutant) + DCC1 + chromosome transmission fidelity proteins<br />
+
**[[6hv8]] - yDpo II subunit A+B – Cryo EM<br />
-
**[[6hv9]] - yDpo II epsilon subunit A+B + CMG + DNA + nucleotide – Cryo EM<br />
+
**[[8xgc]] - yDpo II  in replication origin complex – Cryo EM<br />
-
**[[2r8j]], [[2r8k]], [[4ptf]] - yDpo epsilon catalytic domain + DNA + nucleotide <br />
+
**[[3oha]], [[3ohb]], [[3mfh]] - yDpo (mutant) + DNA<br />
-
**[[6h1v]] - yDpo epsilon catalytic domain (mutant) + DNA + nucleotide <br />
+
**[[6i8a]], [[6qib]], [[7r3x]], [[7r3y]] - yDpo II subunit A + DNA + nucleotide <br />
-
**[[2xgp]], [[2xgq]], [[2wtf]] - yDpo epsilon + DNA<br />
+
**[[6g0a]], [[6fwk]], [[3mfi]], [[4m8o]] - yDpo II subunit A (mutant) + DNA + nucleotide derivative<br />
-
**[[7lxd]] - yDpo eta catalytic+processivity subunits + hDpo d subunits 3+small – Cryo EM<br />
+
**[[6s1c]], [[6s2e]], [[6s2f]] - yDpo II subunit A (mutant) + DCC1 + chromosome transmission fidelity proteins<br />
-
**[[7s0t]] - yDpo eta catalytic+processivity subunits + hDpo d subunits 3+small + DNA – Cryo EM<br />
+
**[[6hv9]] - yDpo II subunit A+B + CMG + DNA + nucleotide – Cryo EM<br />
-
**[[5y27]], [[5y26]] - Dpo epsilon subunit D + transcription factor – fission yeast<br />
+
**[[2r8j]], [[2r8k]], [[4ptf]] - yDpo catalytic domain + DNA + nucleotide <br />
-
**[[1jih]], [[5vtp]] – yDpo catalytic domain<br />
+
**[[6h1v]], [[8b67]], [[8b6k]], [[8b77]], [[8b79]] - yDpo catalytic domain (mutant) + DNA + nucleotide <br />
-
 
+
**[[2xgp]], [[2xgq]], [[2wtf]] - yDpo + DNA<br />
-
*DNA polymerase Rev1; Domains – BRCT 44-133; catalytic 330-833; UBM2 998-1040; C-terminal 1158-1251
+
**[[9b8r]] - yDpo + DNA – Cryo EM<br />
-
 
+
**[[7lxd]] - yDpo  catalytic+processivity subunits + hDpo delta subunits 3+small – Cryo EM<br />
-
**[[3gqc]] – hRev1 catalytic domain + DNA + nucleotide<br />
+
**[[7s0t]] - yDpo  catalytic+processivity subunits + hDpo delta subunits 3+small + DNA – Cryo EM<br />
-
**[[2ebw]] – hRev1 BRCT domain – NMR<br />
+
**[[8tlq]] - yDpo  catalytic+processivity subunits + hDpo delta subunit 3 + DNA + dCTP – Cryo EM<br />
-
**[[6axd]] – hRev1 UBM2 domain – NMR<br />
+
**[[5y27]], [[5y26]] - Dpo subunit D + transcription factor – fission yeast<br />
-
**[[6asr]] – hRev1 UBM2 domain + ubiquitin<br />
+
**[[1jih]], [[5vtp]] – yDpo  catalytic domain<br />
-
**[[5vzm]] – hRev1 UBM2 domain + ubiquitin - NMR<br />
+
**[[8b9b]], [[8kg6]], [[8kg8]], [[8kg9]], [[8w7m]], [[8w7s]] - yDpo III in replisome complex – Cryo EM<br />
-
**[[2lsg]], [[2lsy]] – hRev1 C-terminal domain – NMR<br />
+
-
**[[2n1g]] – hRev1 C-terminal domain + Dpo d subunit 3 – NMR<br />
+
-
**[[2lsi]] – hRev1 C-terminal domain + hDpo kappa peptide <br />
+
-
**[[2lsk]] – hRev1 C-terminal domain + hDpo kappa peptide <br />
+
-
**[[4ext]] – hRev1 C-terminal domain + hDpo eta catalytic subunit peptide + MAD2B<br />
+
-
**[[4gk5]] – hRev1 C-terminal domain + hDpo kappa peptide + hDpo eta catalytic subunit peptide + MAD2B<br />
+
-
**[[2lsj]] – mRev1 C-terminal domain + mDpo kappa peptide <br />
+
-
**[[4fjo]] – mRev1 C-terminal domain + mDpo kappa peptide + MAD2B<br />
+
-
**[[4id3]], [[5umv]] – yRev1 BRCT domain <br />
+
-
**[[2m2i]], [[5vx7]] – yRev1 BRCT domain – NMR<br />
+
-
**[[6x70]], [[6x72]], [[6x73]], [[6x74]], [[6x76]] – yRev1 catalytic domain + DNA <br />
+
-
**[[3bjy]], [[2aq4]], [[3osp]], [[5wm1]], [[5wm8]], [[5wmb]], [[6x6z]], [[6x71]], [[6x75]], [[6x77]] – yRev1 catalytic domain + DNA + nucleotide<br />
+
-
*Terminal deoxynucleotidyl transferase
+
* Terminal deoxynucleotidyl transferase
**[[2coe]] – TdT BRCT domain – NMR<br />
**[[2coe]] – TdT BRCT domain – NMR<br />
**[[1jms]] – mTdT catalytic domain + Mg <br / >
**[[1jms]] – mTdT catalytic domain + Mg <br / >
-
*Terminal deoxynucleotidyl transferase binary complex
+
Terminal deoxynucleotidyl transferase binary complex
**[[4iqt]], [[4iqu]], [[4iqv]], [[4iqw]] – mTdT catalytic domain + inhibitor <br / >
**[[4iqt]], [[4iqu]], [[4iqv]], [[4iqw]] – mTdT catalytic domain + inhibitor <br / >

Revision as of 10:58, 24 April 2025

3D Structures of DNA polymerase

Updated on 24-April-2025

6ctq, 6ctp, 6cto, 6ctn, 6ctm, 6ctl, 6ctk, 6ctj, 6cti, 6crh, 6crc, 6crb, 6cr9, 6cr8, 6cr7, 6cr6, 6cr5, 6cr4, 6cr3, 6cpq, 6cly, 6bem, 6bel, 6ph6, 6u2o, 6u6b, 6uok, 6uol, 6uom, 6w2m, 7k96 - hDpo  + DNA + nucleotide analog

catalytic+2+3+4 + PCNA + DNA + nucleotide analog – Cryo EM

Terminal deoxynucleotidyl transferase binary complex

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman

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