End-binding protein

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Current revision (06:57, 21 May 2025) (edit) (undo)
 
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**[[2qjz]] – hEB1 CH domain 12-133<br />
**[[2qjz]] – hEB1 CH domain 12-133<br />
**[[5n74]] – hEB1 + KAR9 <br />
**[[5n74]] – hEB1 + KAR9 <br />
 +
**[[9co5]] – hEB1 + FKBP12 <br />
**[[1v5k]] – mEB1 CH domain (mutant) – mouse - NMR<br />
**[[1v5k]] – mEB1 CH domain (mutant) – mouse - NMR<br />
**[[6evi]] – mEB1 C-terminal 191-260 - NMR<br />
**[[6evi]] – mEB1 C-terminal 191-260 - NMR<br />
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**[[1wyo]] – hEB3 CH domain - NMR<br />
**[[1wyo]] – hEB3 CH domain - NMR<br />
**[[3jak]], [[7sj9]] – hEB3 + tubulin – Cryo EM <br />
**[[3jak]], [[7sj9]] – hEB3 + tubulin – Cryo EM <br />
 +
**[[9f3r]], [[9f3s]] – hEB3 + tubulin + GTP – Cryo EM <br />
**[[3jal]] – hEB3 + tubulin + GMPCPP – Cryo EM <br />
**[[3jal]] – hEB3 + tubulin + GMPCPP – Cryo EM <br />

Current revision

Human end-binding protein 1 C terminal (grey) complex with dynactin-1 CAP-GLY domain (green) (PDB code 2hkq)

Drag the structure with the mouse to rotate

3D Structures of end-binding protein

Updated on 21-May-2025

References

  1. Nakamura M, Zhou XZ, Lu KP. Critical role for the EB1 and APC interaction in the regulation of microtubule polymerization. Curr Biol. 2001 Jul 10;11(13):1062-7. PMID:11470413
  2. Nehlig A, Molina A, Rodrigues-Ferreira S, Honoré S, Nahmias C. Regulation of end-binding protein EB1 in the control of microtubule dynamics. Cell Mol Life Sci. 2017 Jul;74(13):2381-2393. PMID:28204846 doi:10.1007/s00018-017-2476-2
  3. Goldspink DA, Gadsby JR, Bellett G, Keynton J, Tyrrell BJ, Lund EK, Powell PP, Thomas P, Mogensen MM. The microtubule end-binding protein EB2 is a central regulator of microtubule reorganisation in apico-basal epithelial differentiation. J Cell Sci. 2013 Sep 1;126(Pt 17):4000-14. PMID:23813963 doi:10.1242/jcs.129759

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Michal Harel

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