8zu9

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Current revision (09:09, 2 April 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8zu9 is ON HOLD until Paper Publication
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==The complex structure of MPXV M1R and neutralizing antibody A129==
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<StructureSection load='8zu9' size='340' side='right'caption='[[8zu9]], [[Resolution|resolution]] 2.17&Aring;' scene=''>
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Authors: Ge, J.W.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8zu9]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Monkeypox_virus Monkeypox virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8ZU9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8ZU9 FirstGlance]. <br>
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Description: The complex structure of MPXV M1R and neutralizing antibody A129
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.17&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8zu9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8zu9 OCA], [https://pdbe.org/8zu9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8zu9 RCSB], [https://www.ebi.ac.uk/pdbsum/8zu9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8zu9 ProSAT]</span></td></tr>
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[[Category: Ge, J.W]]
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PG095_MONPV PG095_MONPV] Component of the entry fusion complex (EFC), which consists of 11 proteins. During cell infection, this complex mediates entry of the virion core into the host cytoplasm by a two-step mechanism consisting of lipid mixing of the viral and cellular membranes and subsequent pore formation.[UniProtKB:P07612]
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Monkeypox virus]]
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[[Category: Ge JW]]

Current revision

The complex structure of MPXV M1R and neutralizing antibody A129

PDB ID 8zu9

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