9fqu

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Current revision (05:25, 3 July 2025) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 9fqu is ON HOLD until Paper Publication
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==Cryo-EM structure of MmCAT1 bound with FrMLV-RBD in the arginine-bound inward-occluded state==
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<StructureSection load='9fqu' size='340' side='right'caption='[[9fqu]], [[Resolution|resolution]] 2.79&Aring;' scene=''>
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Authors: Ye, M., Zhou, D., Pike, A.C.W., Wang, S., Wang, D., Bakshi, S., Brooke, L., Williams, E., Elkins, J., Stuart, D.I., Sauer, D.B.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[9fqu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Murine_leukemia_virus Murine leukemia virus] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9FQU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9FQU FirstGlance]. <br>
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Description: Cryo-EM structure of MmCAT1 bound with FrMLV-RBD in the arginine-bound inward-occluded state
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.79&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ARG:ARGININE'>ARG</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=Y01:CHOLESTEROL+HEMISUCCINATE'>Y01</scene></td></tr>
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[[Category: Zhou, D]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9fqu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9fqu OCA], [https://pdbe.org/9fqu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9fqu RCSB], [https://www.ebi.ac.uk/pdbsum/9fqu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9fqu ProSAT]</span></td></tr>
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[[Category: Pike, A.C.W]]
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</table>
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[[Category: Wang, D]]
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== Function ==
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[[Category: Elkins, J]]
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[https://www.uniprot.org/uniprot/CTR1_MOUSE CTR1_MOUSE] High-affinity, low capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine) in non-hepatic tissues.<ref>PMID:1652100</ref> <ref>PMID:1908564</ref> <ref>PMID:9174363</ref> (Microbial infection) Acts as a receptor for the ecotropic murine retroviral leukemia virus.<ref>PMID:1908564</ref> <ref>PMID:2541919</ref> [https://www.uniprot.org/uniprot/GFP_AEQVI GFP_AEQVI] Energy-transfer acceptor. Its role is to transduce the blue chemiluminescence of the protein aequorin into green fluorescent light by energy transfer. Fluoresces in vivo upon receiving energy from the Ca(2+)-activated photoprotein aequorin.
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[[Category: Ye, M]]
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== References ==
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[[Category: Wang, S]]
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<references/>
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[[Category: Bakshi, S]]
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__TOC__
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[[Category: Stuart, D.I]]
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</StructureSection>
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[[Category: Sauer, D.B]]
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[[Category: Large Structures]]
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[[Category: Brooke, L]]
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[[Category: Murine leukemia virus]]
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[[Category: Williams, E]]
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[[Category: Mus musculus]]
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[[Category: Bakshi S]]
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[[Category: Brooke L]]
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[[Category: Elkins J]]
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[[Category: Pike ACW]]
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[[Category: Sauer DB]]
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[[Category: Stuart DI]]
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[[Category: Wang D]]
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[[Category: Wang S]]
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[[Category: Williams E]]
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[[Category: Ye M]]
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[[Category: Zhou D]]

Current revision

Cryo-EM structure of MmCAT1 bound with FrMLV-RBD in the arginine-bound inward-occluded state

PDB ID 9fqu

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