1sui

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[[Image:1sui.gif|left|200px]]
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{{Seed}}
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{{STRUCTURE_1sui| PDB=1sui | SCENE= }}
{{STRUCTURE_1sui| PDB=1sui | SCENE= }}
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'''Alfalfa caffeoyl coenzyme A 3-O-methyltransferase'''
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===Alfalfa caffeoyl coenzyme A 3-O-methyltransferase===
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==Overview==
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Caffeoyl coenzyme A 3-O-methyltransferases (CCoAOMTs) are S-adenosyl-l-methionine-dependent O-methyltransferases (OMTs) involved in lignin biosynthesis. Plant CCoAOMTs belong to a distinct family of OMTs, more closely related to the mammalian catechol OMTs than to other plant OMTs. The crystal structure of alfalfa (Medicago sativa) CCoAOMT in complex with the reaction products S-adenosine-l-homocysteine and feruloyl/sinapoyl CoAs presented here belong to a structurally and mechanistically distinct family of plant small molecule OMTs. These structures provide a new understanding of the substrate preferences and the catalytic mechanism accompanying CCoAOMT-mediated O-methylation of CoA-linked phenylpropanoid substrates.
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The line below this paragraph, {{ABSTRACT_PUBMED_15734921}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 15734921 is the PubMed ID number.
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{{ABSTRACT_PUBMED_15734921}}
==About this Structure==
==About this Structure==
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[[Category: Protein-cofactor-substrate complex]]
[[Category: Protein-cofactor-substrate complex]]
[[Category: Rossmann fold]]
[[Category: Rossmann fold]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 09:08:52 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 12:42:49 2008''

Revision as of 09:42, 29 July 2008

Image:1sui.png

Template:STRUCTURE 1sui

Alfalfa caffeoyl coenzyme A 3-O-methyltransferase

Template:ABSTRACT PUBMED 15734921

About this Structure

1SUI is a Single protein structure of sequence from Medicago sativa. Full crystallographic information is available from OCA.

Reference

Crystal structures of alfalfa caffeoyl coenzyme A 3-O-methyltransferase., Ferrer JL, Zubieta C, Dixon RA, Noel JP, Plant Physiol. 2005 Mar;137(3):1009-17. Epub 2005 Feb 25. PMID:15734921

Page seeded by OCA on Tue Jul 29 12:42:49 2008

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