1svb

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{{STRUCTURE_1svb| PDB=1svb | SCENE= }}
{{STRUCTURE_1svb| PDB=1svb | SCENE= }}
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'''ENVELOPE GLYCOPROTEIN FROM TICK-BORNE ENCEPHALITIS VIRUS'''
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===ENVELOPE GLYCOPROTEIN FROM TICK-BORNE ENCEPHALITIS VIRUS===
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==Overview==
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The crystallographically determined structure of a soluble fragment from the major envelope protein of a flavivirus reveals an unusual architecture. The flat, elongated dimer extends in a direction that would be parallel to the viral membrane. Residues that influence binding of monoclonal antibodies lie on the outward-facing surface of the protein. The clustering of mutations that affect virulence in various flaviviruses indicates a possible receptor binding site and, together with other mutational and biochemical data, suggests a picture for the fusion-activating, conformational change triggered by low pH.
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(as it appears on PubMed at http://www.pubmed.gov), where 7753193 is the PubMed ID number.
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{{ABSTRACT_PUBMED_7753193}}
==About this Structure==
==About this Structure==
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[[Category: Rey, F A.]]
[[Category: Rey, F A.]]
[[Category: Glycoprotein]]
[[Category: Glycoprotein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 09:10:34 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 16:10:19 2008''

Revision as of 13:10, 27 July 2008

Image:1svb.png

Template:STRUCTURE 1svb

ENVELOPE GLYCOPROTEIN FROM TICK-BORNE ENCEPHALITIS VIRUS

Template:ABSTRACT PUBMED 7753193

About this Structure

1SVB is a Single protein structure of sequence from Tick-borne encephalitis virus. Full crystallographic information is available from OCA.

Reference

The envelope glycoprotein from tick-borne encephalitis virus at 2 A resolution., Rey FA, Heinz FX, Mandl C, Kunz C, Harrison SC, Nature. 1995 May 25;375(6529):291-8. PMID:7753193

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