9cyr

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "9cyr" [edit=sysop:move=sysop])
Current revision (13:10, 21 August 2024) (edit) (undo)
 
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 9cyr is ON HOLD
+
==Crystal structure of D245G mutant human PTP1B (PTPN1) at room temperature (298 K)==
-
 
+
<StructureSection load='9cyr' size='340' side='right'caption='[[9cyr]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
-
Authors: Ebrahim, A., Perdikari, A., Woods, V.A., Lawler, K., Bounds, R., Singh, N.I., Mehlman, T., Riley, B.T., Sharma, S., Morris, J.W., Keogh, J.M., Henning, E., Smith, M., Farooqi, I.S., Keedy, D.A.
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[9cyr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9CYR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9CYR FirstGlance]. <br>
-
Description: Crystal structure of D245G mutant human PTP1B (PTPN1) at room temperature (298 K)
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
-
[[Category: Unreleased Structures]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9cyr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9cyr OCA], [https://pdbe.org/9cyr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9cyr RCSB], [https://www.ebi.ac.uk/pdbsum/9cyr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9cyr ProSAT]</span></td></tr>
-
[[Category: Woods, V.A]]
+
</table>
-
[[Category: Mehlman, T]]
+
== Function ==
-
[[Category: Smith, M]]
+
[https://www.uniprot.org/uniprot/PTN1_HUMAN PTN1_HUMAN] Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII- and p60c-src-induced signal transduction cascades. May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion.<ref>PMID:21135139</ref> <ref>PMID:22169477</ref>
-
[[Category: Perdikari, A]]
+
== References ==
-
[[Category: Keedy, D.A]]
+
<references/>
-
[[Category: Morris, J.W]]
+
__TOC__
-
[[Category: Sharma, S]]
+
</StructureSection>
-
[[Category: Ebrahim, A]]
+
[[Category: Homo sapiens]]
-
[[Category: Lawler, K]]
+
[[Category: Large Structures]]
-
[[Category: Henning, E]]
+
[[Category: Bounds R]]
-
[[Category: Farooqi, I.S]]
+
[[Category: Ebrahim A]]
-
[[Category: Singh, N.I]]
+
[[Category: Farooqi IS]]
-
[[Category: Bounds, R]]
+
[[Category: Henning E]]
-
[[Category: Riley, B.T]]
+
[[Category: Keedy DA]]
-
[[Category: Keogh, J.M]]
+
[[Category: Keogh JM]]
 +
[[Category: Lawler K]]
 +
[[Category: Mehlman T]]
 +
[[Category: Morris JW]]
 +
[[Category: Perdikari A]]
 +
[[Category: Riley BT]]
 +
[[Category: Sharma S]]
 +
[[Category: Singh NI]]
 +
[[Category: Smith M]]
 +
[[Category: Woods VA]]

Current revision

Crystal structure of D245G mutant human PTP1B (PTPN1) at room temperature (298 K)

PDB ID 9cyr

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/9cyr"
Personal tools