9ir3
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of Nipah virus L-P polymerase complex== | |
| - | + | <StructureSection load='9ir3' size='340' side='right'caption='[[9ir3]], [[Resolution|resolution]] 3.19Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[9ir3]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Henipavirus_nipahense Henipavirus nipahense]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9IR3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9IR3 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.19Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | [[Category: Peng | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9ir3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9ir3 OCA], [https://pdbe.org/9ir3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9ir3 RCSB], [https://www.ebi.ac.uk/pdbsum/9ir3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ir3 ProSAT]</span></td></tr> |
| - | [[Category: Shi | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PHOSP_NIPAV PHOSP_NIPAV] Essential component of the RNA polymerase transcription and replication complex. Binds the viral ribonucleocapsid and positions the L polymerase on the template (By similarity). May play a role to prevent the establishment of cellular antiviral state by binding to host STAT1 in the cytoplasm. This activity is not as strong as that of V and W. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Henipavirus nipahense]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Peng Q]] | ||
| + | [[Category: Shi Y]] | ||
Current revision
Cryo-EM structure of Nipah virus L-P polymerase complex
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